the disease; and sarcoid of the lungs is a location affected by the
disease. According to a report by the U.S. Department of Health and
Human Services Public Health Service National Institutes of Health:
Sarcoidosis is a disease due to inflammation. It can appear
in almost any body organ, but most often starts in the lungs or lymph
nodes. As sarcoidosis progresses small lumps, or granulomas appear
in the affected tissues. Symptoms are usually general. Weight loss,
fatigue, night sweats, fever, or just an overall feeling of ill health.
In some cases it shows up with the appearance of skin rashes. red
bumps on the face, arms, shins, ect., and sometimes inflammation of
was once considered a rare disease. It is now known to be a common
chronic illness that appears all over the world. It is the most common
of the fibrotic lung disorders, and occurs often enough in the United
States for Congress to have declared a national Sarcoidosis Awareness
Day in 1990. Sarcoidosis is currently (1993) thought to be associated
with an abnormal immune response. Whether a foreign substance; a chemical,
drug, virus, or some other substance is the trigger and how the immune
disturbance is caused are not known. No one can predict how sarcoidosis
will progress. In general, sarcoidosis appears briefly and heals naturally.
However, 20 to 30% of sarcoidosis patients are left with some permanent
lung damage. In 10 to 15% of the patients, sarcoidosis can become severe
and chronic. When either the granulomas or fibrosis seriously affect
the function of a vital organ; the lungs, heart, nervous system, liver,
or kidneys, for example, sarcoidosis can be fatal.
From Ron Hoggan:
repeatedly been associated with celiac disease. Some researchers seem
to view it as a condition which results from untreated celiac disease,
while others see it as coincident with celiac disease. Here are a
couple of references you might want to look at:
- Douglas, et.
al. Sarcoidosis and Celiac Disease: An Association?
Lancet, 1984; July 7:13-15
- Karlish Celiac
Disease and Diffuse Lung Disease Lancet, 1971; May 22: 1077
A Medline search
might reveal more information to you, and I would suggest that you
satisfy yourself of the connection. In #1, it says, in part: These
cases suggest there may be an association between celiac disease
and sarcoidosis, but formal studies of small bowel function in sarcoidosis
are needed to confirm this. It is important to recognize that these
two conditions can occur together and that unexplained weight loss
in a patient with sarcoidosis may be caused by celiac disease.
You might consider suggesting that your friend get a full panel of
blood tests for celiac disease, as it is usually a very treatable
condition. And I have been pleasantly surprised by the resolution
of other, apparently unrelated health problems, that have cleared
up on the diet since I was diagnosed. I hope she is similarly surprised.
- Reunala T,
et al. [See Related Articles] Diseases associated with dermatitis
herpetiformis. Br J Dermatol. 1997 Mar; 136(3): 315-318. PMID: 9115907;
KI, et al. [See Related Articles] The occurrence of polyglandular
autoimmune syndrome type III associated with celiac disease in
patients with sarcoidosis. J Intern Med. 1994 Dec; 236(6): 661-663.
PMID: 7989901; UI: 95081757.
G, et al. [See Related Articles] [Celiac disease (familial) associated
with sarcoidosis. Clinical case and review of the literature]. Minerva
Med. 1994 Oct; 85(10): 541-553. Review. Italian. PMID: 7800197;
A, et al. [See Related Articles] [Sarcoidosis and the digestive
tract]. Gastroenterol Clin Biol. 1994; 18(12): 1119-1128. Review.
French. No abstract available. PMID: 7750685; UI: 95269922.
M, et al. [See Related Articles] Sonographic findings in celiac
disease. J Pediatr Gastroenterol Nutr. 1993 Aug; 17(2): 198-200.
PMID: 8229548; UI: 94046289.
KI, et al. [See Related Articles] Polyglandular autoimmune syndrome
type III associated with celiac disease and sarcoidosis. Postgrad
Med J. 1993 Jan; 69(807): 72-75. PMID: 8446560; UI: 93189522.
- Mainguet P,
et al. [See Related Articles] [Celiac disease in adults: clinical
aspects--role of endoscopy]. Acta Gastroenterol Belg. 1992 Mar;
55(2): 181-189. Review. French. PMID: 1632135; UI: 92336640.
- Sorokin R,
et al. [See Related Articles] Diarrhea presenting as a rare manifestation
of sarcoid. Am J Gastroenterol. 1990 Sep; 85(9): 1197-1198. No abstract
available. PMID: 2389733; UI: 90358167.
- Rogers P,
et al. [See Related Articles] Antibodies to Proteus in rheumatoid
arthritis. Br J Rheumatol. 1988; 27 Suppl 2: 90-94. PMID: 3042079;
- James DG,
et al. [See Related Articles] Overlap syndromes with sarcoidosis.
Postgrad Med J. 1985 Sep; 61(719): 769-771. Review. No abstract
available. PMID: 3903708; UI: 86042375.
- James DG,
et al. [See Related Articles] Overlap syndromes with sarcoidosis.
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- Lowe G, et
al. [See Related Articles] Sarcoidosis and celiac disease. Lancet.
1984 Sep 15; 2(8403): 637. No abstract available. PMID: 6147667;
- [No authors
listed] [See Related Articles] Sarcoidosis and celiac disease.
Lancet. 1984 Aug 18; 2(8399): 408. No abstract available. PMID:
6147488; UI: 84294274.
- Douglas JG,
et al. [See Related Articles] Sarcoidosis and celiac disease: an
association? Lancet. 1984 Jul 7; 2(8393): 13-15. PMID: 6145934;
- Vilaseca J,
et al. [See Related Articles] [Granulomatous hepatitis. Etiologic
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- Hurley TH,
et al. [See Related Articles] Reaction to Kveim test material in
sarcoidosis and other diseases. Lancet. 1975 Mar 1; 1(7905): 494-496.
PMID: 46962; UI: 75117906.
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Related Articles] [Calcium absorption in health and disease. II.
Syndromes of imparied calcium absorption]. Klin Wochenschr. 1974
Jan 15; 52(2): 64-73. Review. German. No abstract available. PMID:
4361437; UI: 74122902.
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et al. [See Related Articles] [A case of peripheral neuropathy during
terminal ileitis. Crohns disease]? Sem Hop. 1973 Jun 26; 49(30):
2209-2218. French. No abstract available. PMID: 4147181; UI: 73252730.
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et al. [See Related Articles] The Kveim test in Crohns disease,
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AS, et al. [See Related Articles] In vitro inhibition of leucocyte
migration by sarcoid spleen suspension in celiac disease and dermatitis
herpetiformis. Lancet. 1971 Nov 27; 2(7735): 1179-1181. No abstract
available. PMID: 4107984; UI: 72052439.
- Karlish AJ.
[See Related Articles] Celiac disease and diffuse lung disease.
Lancet. 1971 May 22; 1(7708): 1077. No abstract available. PMID:
4103011; UI: 71206245.
- Dawson AM.
[See Related Articles] Nutritional disturbances in Crohns disease.
Proc R Soc Med. 1971 Feb; 64(2): 166-170. No abstract available.
PMID: 5548941; UI: 71139887.
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Related Articles] Hypogammaglobulinaemia in the United Kingdom.
3. Clinical features of hypogammaglobulinaemia. Med Res Counc Spec
Rep Ser (Lond). 1971; 310: 9-34. No abstract available. PMID: 5573491;
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[See Related Articles] Urinary excretion of free and conjugated
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et al. [See Related Articles] Whipples disease. Med J Aust. 1967
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[See Related Articles] Sarcoidosis with recurrent thrombophlebitis
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