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- Natural Killer Cell Activity in Celiac Disease - Czech Republic
Natural Killer Cell Activity in Celiac Disease - Czech Republic
- By Scott Adams
- Published 07/26/1996
- Celiac Disease & Gluten Intolerance Research
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Scott Adams
In 1994 I was diagnosed with celiac disease, which led me to create Celiac.com in 1995. I created this site for a single purpose: To help as many people as possible with celiac disease get diagnosed so they can begin to live happy, healthy gluten-free lives. Celiac.com was the first site on the Internet dedicated solely to celiac disease, and since then it has become an invaluable resource to people worldwide who seek information about celiac disease and the gluten-free diet.
In 1998 I created The Gluten-Free Mall, Your Special Diet Superstore! which was also another Internet first—it was the first gluten-free food site to offer a shopping cart-style interface, and the ability for people to order gluten-free products manufactured by many different companies at a single Web site.
I am also co-author of the book Cereal Killers, and founder and publisher of Journal of Gluten Sensitivity.
Castany M, Nguyen H, Pospisil
M, Fric P, Tlaskalova-Hogenova H
Natural killer cell activity in coeliac disease: effect
of in vitro treatment on effector lymphocytes and/or target
lymphoblastoid, myeloid and epithelial cell lines with gliadin
Folia Microbiol, 1995 (Praha) 40; 6: 615-620.
In this study researchers tested the levels of natural killer cell activation in normal people and compared the results with treated celiacs, and found no significant difference. However, after exposing the celiacs blood to gliadin for thirty minutes the researchers found a reduced activation of natural killer cells, which is the bodys first line of defense against malignancy. These results provide further support to the theory that gluten is a carcinogen to celiacs.
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2 Responses to "Natural Killer Cell Activity in Celiac Disease - Czech Republic"
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said this on 26 Jun 2010 1:21:05 AM PDT
I was just diagnosed with celiac disease a few weeks ago. Later I had a blood test, where I found out that my natural kill cells were next to nothing. According to the doctor a normal number would be a least 100, to have twenty was bad. My test results said I had less that 5. So, my doctor started me on immune globulin shots to try to bring up natural kill cell numbers. I am also on a gluten-free diet. So, hopefully I am going to see some changes.
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said this on 28 Jun 2010 8:42:43 PM PDT
I found another group of doctors that did a similar test to the 1995 test that is talked about above. The name of the doctors Grose RH, Thompson FM, Cummins AG. in Department of Gastroenterology and Hepatology, The Queen Elizabeth Hospital, University of Adelaide, Woodville South, SA 5011, Australia. 2007. Here is a link to those results "Deficiency of 6B11+ invariant NK T-cells in celiac disease" I myself have celiac disease, and my last blood test shows that I have very low Natural killer cells way below the normal number. I wonder if that could be a precursor to intestinal cancer? I hope not. . .
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