One case I know of had elevated gliadins (both types) but normal EMA and ARA, plus an inconclusive biopsy. Do you see this often?**
http://www.celiac.com/articles/15/1/One-case-I-know-of-had-elevated-gliadins-both-types-but-normal-EMA-and-ARA-plus-an-inconclusive-biopsy-Do-you-see-this-often/Page1.html
Scott Adams
In 1994 I was diagnosed with celiac disease, which led me to create Celiac.com in 1995. I created this site for a single purpose: To help as many people as possible with celiac disease get diagnosed so they can begin to live happy, healthy gluten-free lives. Celiac.com was the first site on the Internet dedicated solely to celiac disease, and since then it has become an invaluable resource to people worldwide who seek information about celiac disease and the gluten-free diet. In 1998 I created The Gluten-Free Mall, Your Special Diet Superstore! which was also another Internet first—it was the first gluten-free food site to offer a shopping cart-style interface, and the ability for people to order gluten-free products manufactured by many different companies at a single Web site.
I am also co-author of the book Cereal Killers, and founder and publisher of Journal of Gluten Sensitivity.
By Scott Adams
Published on 07/26/1996
Vijay Kumar, M.D., Research Associate Professor
at the University of Buffalo and President and Dir
One case I know of had elevated gliadins (both types) but normal EMA and ARA, plus an inconclusive biopsy. Do you see this often?**
Vijay Kumar, M.D., Research Associate Professor
at the University of Buffalo and President and Director of IMMCO
Diagnostics: If the tests are performed using well standardized
tests with known positive and negative predictive values then
you can make the statement that if the serological tests are negative
celiac disease can virtually be ruled out. The problem is that some of these
assays, especially the gliadin, can give you false positive results.
In our laboratory we rarely see positive AGA results in the absence
of EMA and ARA antibodies.