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    Scott Adams
    Scott Adams

    Seroconversion of Reticulin Autoantibodies Predicts Celiac Disease in Insulin Dependent Diabetes Mellitus

    Reviewed and edited by a celiac disease expert.

    Mdki M, Hupponen T; Holm K, Hallstrom O, _Gut_ 1995; Feb 3692) pgs. 239-42

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    In a study of 238 children and adolescents with insulin dependent diabetes mellitus (IDDM), serum IgA reticulin antibody tests were performed once a year. During the initial testing, within one year of the onset of IDDM, 5 children (2%) were positive. During follow up, 11 of the antibody-negative children (5%) became positive; of these 9 were shown to have silent celiac disease by jejunal biopsies. This study suggests that repeated serological screening and biopsies should be considered to detect late developing, clinically silent celiac disease among patients with IDDM.



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  • About Me

    Scott Adams

    Scott Adams was diagnosed with celiac disease in 1994, and, due to the nearly total lack of information available at that time, was forced to become an expert on the disease in order to recover. In 1995 he launched the site that later became Celiac.com to help as many people as possible with celiac disease get diagnosed so they can begin to live happy, healthy gluten-free lives.  He is co-author of the book Cereal Killers, and founder and publisher of the (formerly paper) newsletter Journal of Gluten Sensitivity. In 1998 he founded The Gluten-Free Mall which he sold in 2014. Celiac.com does not sell any products, and is 100% advertiser supported.


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