- Celiac Disease Research: Associated Diseases and Disorders
- Diabetes and Celiac Disease
- Gluten-Sensitive Enteropathy in Patients with Insulin-Dependent Diabetes Mellitus
Gluten-Sensitive Enteropathy in Patients with Insulin-Dependent Diabetes Mellitus
In 1994 I was diagnosed with celiac disease, which led me to create Celiac.com in 1995. I created this site for a single purpose: To help as many people as possible with celiac disease get diagnosed so they can begin to live happy, healthy gluten-free lives. Celiac.com was the first site on the Internet dedicated solely to celiac disease. In 1998 I foundedÂ The Gluten-Free Mall, Your Special Diet Superstore!, and I am the co-author of the book Cereal Killers, and founder and publisher of Journal of Gluten Sensitivity.View all articles by Scott Adams
Author: Rensch MJ; Merenich
JA; Lieberman M; Long BD; Davis DR; McNally PR.
Address: Fitzsimons Army Medical Center, Aurora, Colorado, USA.
Source: Ann Intern Med, 124: 6, 1996 Mar 15, 564-7
OBJECTIVE: To determine the prevalence of celiac disease in a cohort of patients with insulin-dependent diabetes mellitus and to describe the clinical characteristics of patients with coexistent disease.
DESIGN: Prospective cohort study.
SETTING: U.S. Army medical center.
PATIENTS: 47 patients with insulin-dependent diabetes mellitus.
RESULTS: 3 of 47 patients with insulin-dependent diabetes mellitus (6.4%; 95% CI, 1.4% to 17.5%) had positive antiendomysial antibody test results and small-bowel biopsy specimens consistent with celiac disease. The 95% CI lies entirely above the estimated prevalence of celiac disease expected in the general U.S. population, which ranges from 0.02% to 0.1%. Mean bone mineral densities were 0.8 and 1.1 SD below age-, ethnicity-, and sex-matched controls in each of the 2 antiendomysial antibody-positive patients tested. Small bowel absorption was abnormal in 1 of the 2 patients tested by D-xylose. Anemia and hypoalbuminemia were not detected in any of the patients with coexistent disease. Only 1 of the 3 patients had symptoms of diarrhea. All patients were at or above their ideal body weights.
CONCLUSIONS: Celiac disease appears to be more common among patients with insulin-dependent diabetes mellitus than in the general U.S. population (p less than 0.001). Two of the three patients with coexistent disease in this study had sub-clinical or latent celiac disease.
As always, Celiac.com welcomes your comments (see below).
- Patients with Celiac Disease Have Lower Rates of Non–Insulin-Dependent Diabetes Mellitus and Metabolic Syndrome
- Anti-infectious and Autoimmune-associated Autoantibodies in Patients with Type I Diabetes Mellitus and Celiac Disease
- Risk Markers for Insulin-Dependent Diabetes Mellitus and Duration of Exposure to Gluten in Celiac Patients