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- Prevalence of Hypertransaminasemia in Adult Celiac Patients and Effect of Gluten-Free Diet
Prevalence of Hypertransaminasemia in Adult Celiac Patients and Effect of Gluten-Free Diet
- By Scott Adams
- Published 07/26/1996
- Liver Disease and Celiac Disease
- Unrated
Scott Adams
In 1994 I was diagnosed with celiac disease, which led me to create Celiac.com in 1995. I created this site for a single purpose: To help as many people as possible with celiac disease get diagnosed and living happy, healthy gluten-free lives. Celiac.com was the first site on the Internet dedicated solely to celiac disease, and since then it has become an invaluable resource to people worldwide who seek information about celiac disease and the gluten-free diet.
In 1998 I created The Gluten-Free Mall, Your Special Diet Superstore! which was also another Internet first—it was the first gluten-free food site to offer a shopping cart-style interface, and the ability for people to order gluten-free products manufactured by many different companies at a single Web site.
Prevalence of Hypertransaminasemia in Adult Celiac Patients and Effect of Gluten-Free Diet
Author: Bardella MT; Fraquelli M; Quatrini
M; Molteni N; Bianchi P; Conte D
Address: Cattedra di Gastroenterologia, Universit a degli Studi
di Milano, IRCCS Ospedale Maggiore, Italy.
Source: Hepatology, 1995 Sep, 22:3, 833-6
The prevalence of hypertransaminasemia and the effect of gluten-free diet (GFD) were evaluated in 158 consecutive adult celiac patients, 127 women and 31 men, aged 18 to 68 years (mean, 32). At diagnosis, 67 patients (42%) had raised aspartate and/or alanine transaminase levels (AST and ALT; mean, 47 IU/L, range, 30 to 190; and 61 IU/L, range, 25 to 470, respectively), whereas 91 patients had normal liver function tests (LFT). Patients with and without hypertransaminasemia were comparable for epidemiological data, body mass index (18.5 vs. 19.6), and severity of intestinal histological involvement. All patients were given a strict GFD and were followed for 1 to 10 years (median, 4). At 1 year, a highly significant improvement in intestinal histology was observed in both groups.
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