- Celiac Disease Research: Associated Diseases and Disorders
- Cancer, Lymphoma and Celiac Disease
- Malignancy in Celiac Disease -- Effect of a Gluten-Free Diet
Malignancy in Celiac Disease -- Effect of a Gluten-Free Diet
In 1994 I was diagnosed with celiac disease, which led me to create Celiac.com in 1995. I created this site for a single purpose: To help as many people as possible with celiac disease get diagnosed so they can begin to live happy, healthy gluten-free lives. Celiac.com was the first site on the Internet dedicated solely to celiac disease, and since then it has become an invaluable resource to people worldwide who seek information about celiac disease and the gluten-free diet.
In 1998 I created The Gluten-Free Mall, Your Special Diet Superstore! which was also another Internet first—it was the first gluten-free food site to offer a shopping cart-style interface, and the ability for people to order gluten-free products manufactured by many different companies at a single Web site.
I am also co-author of the book Cereal Killers, and founder and publisher of Journal of Gluten Sensitivity.
Holmes GK, Prior P, Lane MR,
Pope D, Allan RN
Gut 1989 Mar;30(3):333-8
Gastroenterology Unit, General Hospital, Birmingham.
PMID: 2707633, UI: 89212172
hundred and ten patients with coeliac disease previously reported
from this unit were reviewed at the end of 1985 after a further
11 years of follow up. The initial review at the end of 1974
could not demonstrate that a gluten free diet (GFD) prevented
these complications, probably because the time on diet was relatively
short. The same series has therefore been kept under surveillance
with the particular aim of assessing the effects of diet on
malignancy after a further prolonged follow up period. Twelve
new cancers have occurred: of which one was a carcinoma of the
esophagus and two lymphomas. Thirty nine cancers developed
in 38 patients and of 69 deaths, 33 were the result of malignancy.
A two-fold relative risk (RR) of cancer was found and was because
of an increased risk of cancer of the mouth and pharynx (RR
= 9.7, p less than 0.01, 95% confidence interval (CI) = 2.0-28.3),
esophagus (RR = 12.3, p less than 0.01, CI = 2.5-36.5), and
of non-Hodgkins lymphoma (RR = 42.7, p less than 0.001, CI
= 19.6-81.4). The results indicate that for coeliac patients
who have taken a GFD for five years or more the risk of developing
cancer over all sites is not increased when compared with the
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