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The Provocation Test in Children with Cow-Milk Protein and Gluten Intolerance: Evaluation of the Clinical Response and Lesions in the Mucous Membrane of the Small Intestine

TI- Proba prowokacyjna u dzieci z nietolerancja biaLek mleka krowiego i glutenu: ocena reakcji
klinicznych i zmian w bLonie sluzowej jelita cienkiego.
AU- Kaczmarski M
CS- Kliniki Chorob Zakaznych Dzieci AM w BiaLymstoku.
JN- Pol Tyg Lek; 45 (8-9) p161-5
PY- Feb 19-26 1990

AB- Provocation test (re-introduction of the noxious protein) was carried out in two groups of patients: (a) with intolerance to the cow-milk proteins (41 children) treated with milk-free diet for 6-24 months, and (b) with gluten intolerance (26 children) treated with gluten-free diet for 6-36 months. The following parameters were compared: type and frequency of the clinical symptoms seen in these patients prior to the introduction of allergen-free diet. Moreover, the type of observed morphological changes in the small intestine

in mucous glands lining all body cavities or passages that communicate with the exterior that functions in protection, support, nutrient absorption, and secretion of mucus, enzymes, and salts (such as the alimentary, respiratory, and genitourinary tracts).'); return false">mucosa following provocation test were analyzed in the groups of 7 patients. A two-year elimination of milk from the diet produces milk tolerance in about 61% patients; clinical symptoms in the remaining children are diversified. Re-introduction of gluten with the diet (provocation test) produces recurrence of gluten intolerance in 96% of children treated with gluten-free diet for 2-3 years. Recurrence of the disease was accompanied by the atrophy of the intestinal villi.

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