Celiac.com 03/05/2010 - A team of researchers recently studied the relationship between increased levels of antigliadin antibodies and intestinal barrier gene variants.

The research team included V. M. Wolters, B. Z. Alizadeh, M. E. Weijerman, A. Zhernakova, I. M. van Hoogstraten, M. L. Mearin, M. C. Wapenaar, C.Wijmenga, M. W. Schreurs. They are affiliated with the Department of Pediatric Gastroenterology, UMC Utrecht, Utrecht, The Netherlands.

Numerous genes may affect intestinal barrier function, including MAGI2, MYO9B, and PARD3, which have a close association with celiac disease. Gauging intestinal permeability is tough to do, so researchers can test indirectly by using antibodies against