Jump to content
This site uses cookies. Continued use is acceptance of our Terms of Use and Privacy Policy. More Info... ×
  • Welcome to Celiac.com!

    You have found your celiac tribe! Join us and ask questions in our forum, share your story, and connect with others.




  • Celiac.com Sponsor (A1):



    Celiac.com Sponsor (A1-M):


  • Get Celiac.com Updates:
    Help Celiac.com:
    eNewsletter
    Donate
  • Record is Archived

    This article is now archived and is closed to further replies.

    Jefferson Adams
    Jefferson Adams

    Most People with Celiac Disease Open to Pharmaceutical Treatments

    Reviewed and edited by a celiac disease expert.
    Most People with Celiac Disease Open to Pharmaceutical Treatments - Image: Wikimedia Commons
    Caption: Image: Wikimedia Commons

    Celiac.com 10/17/2013 - A gluten-free diet is till the only treatment for celiac disease, but a number of companies are working on pharmaceutical treatments. However, very little information exists bout the level of interest among patients in using a medication to treat celiac disease.

    Image: Wikimedia CommonsA research team set out to assess interest levels among patients in medical treatments for celiac disease. The research team included Christina A. Tennyson, Suzanne Simpson, Benjamin Lebwohl, Suzanne Lewis and Peter H. R. Green.

    Celiac.com Sponsor (A12):
    For their study, the researchers submitted a questionnaire to celiac disease patients and collected data on demographics, presentation, and interest in medication. The questionnaire included three validated celiac disease-specific instruments: Celiac Disease Associated Quality of Life, the Celiac Symptom Index, and the Celiac Dietary Adherence Test.

    The team received 365 responses from people with biopsy-proven celiac disease. A total of 276 women and 170 men over 50 years of age responded to the study. Of these respondents, 154 experienced classic, diarrhea predominant celiac disease. In all 339 people responded to the question asking if they were interested in using a medication to treat celiac disease, 66% of whom indicated that they were interested.

    The questionnaire responses broke down as follows:

    • Older people showed the greatest interest, with 71% of people over 50 years of age saying they were interested, compared with 60% of people under 50 years of age, (p = 0.0415).
    • More men (78%) than women (62%) women were interested (p = 0.0083).
    • People who ate out frequently (76%) showed a greater interest than those who did not (58%), p = 0.0006).
    • People dissatisfied with their weight showed greater interest (73%) than those satisfied with their weight (51%), (p = 0.0003)
    • Lastly, those concerned with gluten-free diet costs (77%) showed greater interest than those not concerned about gluten-free diet costs (64%), (p = 0.0176).

    Interestingly, the list of factors that did not seem to influence interest included length of time since diagnosis, education, presentation, and symptoms with gluten exposure.

    Overall, celiacs with lower quality of life scores showed a higher interest in medication (celiac disease-QOL 69.4 versus 80.1, p < 0.0001).

    This survey shows a fairly strong interest among people with celiac disease in non-dietary, medical treatments.

    Interest was highest among men, older individuals, frequent restaurant customers, individuals dissatisfied with their weight or concerned with the cost of a gluten-free diet, and those with a worse quality of life.

    Just how well any drugs developed to treat celiac disease might be received will likely depend on many factors, including efficacy, side-effects, cost, ease of use, etc.

    Source:

    •  Open Original Shared Link


    User Feedback

    Recommended Comments

    Guest harparshantvir singh

    Posted

    Very well researched article. Indian herbal medicines have good results in celiac disease. Unfortunately people in western world don't seem to believe in this system of medicine.

    Link to comment
    Share on other sites
    Guest Donnie

    Drug approvals are often fast-tracked by the FDA, and we later find out that they are not safe or effective. And some drugs have caused severe side effects, including many deaths. A few have been pulled from the market, but most have not. I am not interested in trying any new drugs. After several years, the safety and effectiveness, or serious risks of the drug will be more apparent. Then I might consider trying it, if it proves to be safe.

    Link to comment
    Share on other sites
    Guest laurie

    I think it is very important to find a cure. I am finding out how difficult my teenage daughter's life has become (and my life as well, trying to feed her) and am worried when she eats at others' houses and out at restaurants. This disease definitely affects quality of life!

    Link to comment
    Share on other sites
    Guest Carrie

    We need to correct the issues with our food supply and we don't need another drug.

    Link to comment
    Share on other sites
    Guest Kelly

    I would welcome a drug treatment, depending upon side effects. I would take it prophalactically and still eat as little gluten as possible. I have to dine out a lot and the occassional error is painful for me.

    Link to comment
    Share on other sites


    Guest
    This is now closed for further comments

  • Get Celiac.com Updates:
    Help Celiac.com:
    Donate
  • About Me

    Jefferson Adams

    Jefferson Adams is Celiac.com's senior writer and Digital Content Director. He earned his B.A. and M.F.A. at Arizona State University. His articles, essays, poems, stories and book reviews have appeared in numerous magazines, journals, and websites, including North American Project, Antioch Review, Caliban, Mississippi Review, Slate, and more. He is the author of more than 2,500 articles on celiac disease. His university coursework includes studies in science, scientific methodology, biology, anatomy, physiology, medicine, logic, and advanced research. He previously devised health and medical content for Colgate, Dove, Pfizer, Sharecare, Walgreens, and more. Jefferson has spoken about celiac disease to the media, including an appearance on the KQED radio show Forum, and is the editor of numerous books, including "Cereal Killers" by Scott Adams and Ron Hoggan, Ed.D.

    >VIEW ALL ARTICLES BY JEFFERSON ADAMS

     


  • Celiac.com Sponsor (A17):
    Celiac.com Sponsor (A17):





    Celiac.com Sponsors (A17-M):




  • Related Articles

    Jefferson Adams
    Celiac.com 06/26/2007 - In a study published recently in the Scandinavian Journal of Gastroenterology, researchers found that celiac patients commonly have high rates of anti-Saccharomyces cerevisiae antibodies (ASCA). A team of researchers recently set out to assess the frequency anti-Saccharomyces cerevisiae antibodies (ASCA) in patients with celiac disease.
    The team was made up of Dorsaf Toumi; Amani Manka&IUML;; Ramla Belhadj; Leila Ghedira-Besbes; Moncef Jeddi; and Ibtissem Ghedira. They used ELISA to evaluate blood serum for ASCA, IgG and IgA in 238 patients with celiac disease. The team used 80 non-celiac blood donors as a control group. The 238 study subjects were divided into separate groups as follows: 125 untreated celiac patients; 42 celiac patients following...


    Jefferson Adams
    Celiac.com 06/30/2008 - The results of a Hungarian study published recently in the June issue of Pediatrics suggest that people with untreated celiac disease show abnormal resistance to the hepatitis B (HBV) vaccine, while celiac patients on a gluten-free diet show a near normal response to the vaccine.
    A team of doctors led by Dr. Eva Nemes, at the University of Debrecen, administered 2 to 3 doses of recombinant HBV vaccine to 128 patients with celiac disease and an age matched control group of 113 non-celiac patients within a 6-month period. Twenty-two of the celiac patients were following a gluten-free diet when they received the vaccine.
    One month after the last HBV vaccination, the team took blood samples to look for anti-HBV antibodies. The group of 22 patients who received...


    Jefferson Adams
    Celiac.com 07/28/2010 - Most people with celiac disease keep themselves healthy by following a gluten free diet. More and more, doctors are recognizing the importance of confirming gut recovery through follow-up evaluation. Still, among clinicians, there is currently no standard for follow-up confirmation of gut healing in celiac disease treatment.
    Many guidelines recommend an initial follow-up biopsy at 4-6 months after the patient begins a gluten-free diet. However, the use of biopsy to confirm gut healing is still controversial, as it can yield enormously variable results.
    A group of researchers recently set out to establish the amount of time it takes for full gut recovery in patients with celiac disease.
    The research team was made up of J.M. Hutchinson, N.P. West, G.G...


    Jefferson Adams
    Celiac.com 02/10/2012 - The HBV vaccine is usually effective against common hepatitis B virus (HBV) infection, with just 4-10% of vaccine recipients failing to respond to standard immunization. Some studies suggest that people with celiac disease may have high levels of resistance to the HBV vaccine, compared to the general population.
    A team of researchers recently took a look at the issue of HBV vaccine reliability in people with celiac disease.
    The study team included Mohammad Rostami Nejad, Kamran Rostami, and Mohammad Reza Zali. They are variously affiliated with the Research Center for Gastroenterology and Liver Disease at Shahid Beheshti University of Medical Sciences in Tehran, Iran, and with Acute Medicine at Dudley Group of Hospital in Dudley, UK. Together, they reviewed...


  • Recent Activity

    1. - Hannah24 replied to Hannah24's topic in Celiac Disease Pre-Diagnosis, Testing & Symptoms
      7

      Negative Test but I have All the Symptoms!

    2. - Hannah24 replied to Hannah24's topic in Celiac Disease Pre-Diagnosis, Testing & Symptoms
      7

      Negative Test but I have All the Symptoms!

    3. - trents replied to Linedancegal's topic in Introduce Yourself / Share Stuff
      4

      25 year biopsy confirmed/ate pizza with no ill effects?

    4. - Moodiefoodie replied to Moodiefoodie's topic in Related Issues & Disorders
      2

      Joint swelling when ill even on gluten-free diet

    5. - knitty kitty replied to Holly15892's topic in Post Diagnosis, Recovery & Treatment of Celiac Disease
      7

      Growth spurt after diagnosis in adulthood


  • Celiac.com Sponsor (A19):



  • Member Statistics

    • Total Members
      120,466
    • Most Online (within 30 mins)
      7,748

    CtoThaE
    Newest Member
    CtoThaE
    Joined

  • Celiac.com Sponsor (A20):


  • Forum Statistics

    • Total Topics
      120.2k
    • Total Posts
      1m

  • Celiac.com Sponsor (A22):





  • Celiac.com Sponsor (A21):



  • Popular Now

    • Linedancegal
    • Hannah24
      7
    • jessiemariecar
    • Rhonda H
    • HayleyC123
  • Popular Articles

    • Scott Adams
    • Scott Adams
    • Scott Adams
    • Scott Adams
    • Scott Adams
  • Upcoming Events

×
×
  • Create New...