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AGILE Clinical Research Trials: Research Study on Celiac Disease
http://www.celiac.com/articles/23649/1/AGILE-Clinical-Research-Trials-Research-Study-on-Celiac-Disease/Page1.html
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By Advertising Banner-Ads
Published on 06/1/2014
 

AGILE Clinical Research Trials is conducting a research study on Celiac Disease. The study “Efficacy and Safety of XXXX drug Treatment in Symptomatic Celiac Disease Patients Maintained on a Gluten-Free Diet”


AGILE Clinical Research Trials is conducting a research study on Celiac Disease. The study “Efficacy and Safety of XXXX drug Treatment in Symptomatic Celiac Disease Patients Maintained on a Gluten-Free Diet”

Agile Clinical ResearchIf you want to know more about this study, please contact us: 404.400.2255 or Visit: http://www.agilecrt.com/current-trials.php

Celiac disease is an acquired chronic immune disorder that develops in susceptible individuals after exposure to gluten, a family of proteins in wheat, barley and rye that are especially abundant in glutamine and proline. Numerous gluten epitopes are resistant to digestion by gastric, pancreatic, and intestinal brush border membrane proteases. Consequently, gluten-derived immunogenic oligopeptides accumulate and trigger a specific T lymphocyte driven immune response in the intestine of celiac disease patients. Gliadin is the alcohol soluble fraction of gluten that contains the bulk of the immunogenic peptides.

The prevalence of celiac disease in the United States is estimated to be approximately 1% of the population, and it has a wide range of clinical manifestations. For all patients, celiac disease is a lifelong disease, and unless complete gluten exclusion is strictly followed, patients are at enhanced risk for the development of further complications, such as bone disorders, infertility, cancer and increased mortality. At this time there is no therapy for celiac disease other than a gluten exclusion diet.

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