Jump to content
This site uses cookies. Continued use is acceptance of our Terms of Use and Privacy Policy. More Info... ×
  • Welcome to Celiac.com!

    You have found your celiac tribe! Join us and ask questions in our forum, share your story, and connect with others.




  • Celiac.com Sponsor (A1):



    Celiac.com Sponsor (A1-M):


  • Get Celiac.com Updates:
    Help Celiac.com:
    eNewsletter
    Donate
  • Record is Archived

    This article is now archived and is closed to further replies.

    Jefferson Adams
    Jefferson Adams

    Pregnancy Complications More Common in Women with Celiac Disease

    Reviewed and edited by a celiac disease expert.

    Celiac.com 04/27/2015 - We know that women with infertility have higher rates of celiac disease than women who are not infertile.

    Photo: CC--Christy SpencerThere's been some evidence to suggest that celiac disease might have impact women's reproductive health. However, the quest for more solid answers continues.

    Celiac.com Sponsor (A12):
    A team of researchers recently set out to assess fertility and outcomes of pregnancy among women with celiac disease. The research team included Stephanie M. Moleski, Christina C. Lindenmeyer, J. Jon Veloski, Robin S. Miller, Cynthia L. Miller, David Kastenberg, and Anthony J. DiMarino. The team crafted a retrospective cohort study in which they analyzed information gathered from patients at a tertiary care celiac center, along with information gathered from members of two national celiac disease awareness organizations.

    A group of women without celiac disease served as control subjects. Both groups answered an anonymous online survey of 43 questions about menstrual history, fertility, and pregnancy outcomes. The group included 329 women with small bowel biopsy-confirmed celiac disease and 641 control subjects. Of the 970 women included in the study, 733 (75.6%) reported that they had been pregnant at some point.

    In terms of pregnancy, there was no significant difference between women with celiac disease (n=245/329, 74.5%) and controls (488/641, 76.1%; P=0.57). However, fewer women with celiac disease than controls (79.6% vs. 84.8%) reported giving birth following 1 or more pregnancies (P=0.03).

    Women with celiac disease had higher rates of spontaneous abortion than did control subjects (50.6% vs. 40.6%; P=0.01). Women with celiac disease also had higher rates of premature delivery, at 23.6% compared to 15.9% among controls (P=0.02).

    The average age at menarche was a bit higher in the celiac disease group, at 12.7 years, than in the control group, which came in at 12.4 years (P=0.01).

    This retrospective cohort analysis examining reproductive features of women with celiac disease, found that celiac disease was associated with significant increases in spontaneous abortion, premature delivery, and later age of menarche.

    Source:

    • Open Original Shared Link


    User Feedback

    Recommended Comments

    Guest Jen

    It's not clear whether the women with celiac had been following a gluten-free diet. In other words, were they "healthy" before becoming pregnant, or suffering from symptoms of untreated celiac disease?

    Link to comment
    Share on other sites
    Guest Jefferson Adams

    Posted

    I agree it would be helpful to know more about the gluten-free status of these women, and whether that has any impact on outcomes. I imagine women with celiac disease who follow a gluten-free diet would have similar rates of normal pregnancy as the non-celiac controls, but that's just a guess.

    Link to comment
    Share on other sites
    Guest sheri

    Posted

    I would like someone to do research on Preeclampsia and toximia, I don't know if I have celiac disease but I am sensitive to gluten. I am also dairy, soy, corn and some other foods I am allergic to. When I had my children I did not know that I was sensitive or allergic, I was just sick my whole life and got preeclampsia. I wonder if foods cause this?

    Link to comment
    Share on other sites
    Guest Christine

    Posted

    There's room for investigating if the dreaded nine-months morning sickness could also be attributed to coeliac disease, treated or otherwise. I was subsequently diagnosed with celiac disease, so was my sister and daughter who like me also suffered from the appalling long term morning sickness; we would have been in good company with the Duchess of Cambridge, but it would've been no consolation at the time.

    Link to comment
    Share on other sites
    Guest Sharon

    Posted

    I had symptoms of celiac ever since I was 9 but didn't know what it was until I was 68. I had toxemia when I was 7 months pregnant and lost that baby. The baby weighed 2 pounds. The second baby was also stillborn, they thought I could deliver it the normal way, but I couldn't, they had to do a C-section, he was 3 pounds when I was 7 months. The 3rd baby was 4 pounds at 8 months, and lived. I think all my babies were small because they weren't getting enough nourishment because of being celiac.

    Link to comment
    Share on other sites
    Guest NC Mtn. Momma

    Posted

    I was diagnosed with Celiac at age 62. I didn't know what it was, but from the time I had my first period at age 11.5, I ate like a line backer. I am 75 years old, 5'1" & weigh 117#. I ate more than my older sister who could look at food & gain weight. As a teen, I  would pack a large lunch & buy a hot lunch including 2 cartons of milk. I never gained an ounce.  I wore a size 3. At. 23 I had my 1st child two days before my due date & she weighed 8# 2.5 oz. I had very mild nausea  & it was gone by week 12.  I had a miscarriage 2 years later.  I got pregnant again & had a baby girl five days before my due date with a little  help from my doctor who thought I was gaining too much weight (40#). The baby weighed 8# 5oz.  At my 6 week checkup I weighed 105 & they said don't lose any more weight. I went back to my pre pregnancy weight of 97#.  I never tried to lose weight.  I also never tried to get pregnant. I had always tried not to get pregnant.   I wasn't nauseous. I had natural childbirth in 6 hours & 2 hours labor. I never fit the norm in anything.  People said I had a fast metabolism, because I could eat anything & never gain weight. 
    I think I had Celiac since I was 11.  I never had any symptoms. At age 62, I was being treated for fibromyalgia & kept getting worse. My rheumatologist tested me for Celiac, Lupus & R/A. My celiac numbers were over 100. Thirteen years later my numbers are <2, but being gluten free, my digestive system isn't normal. All those years of consuming gluten must have damaged my gut. I also have Hashimotos and am otherwise in good health. No fibromyalgia & I still don't fit the norm. 

    Link to comment
    Share on other sites


    Guest
    This is now closed for further comments

  • Get Celiac.com Updates:
    Help Celiac.com:
    Donate
  • About Me

    Jefferson Adams

    Jefferson Adams is Celiac.com's senior writer and Digital Content Director. He earned his B.A. and M.F.A. at Arizona State University. His articles, essays, poems, stories and book reviews have appeared in numerous magazines, journals, and websites, including North American Project, Antioch Review, Caliban, Mississippi Review, Slate, and more. He is the author of more than 2,500 articles on celiac disease. His university coursework includes studies in science, scientific methodology, biology, anatomy, physiology, medicine, logic, and advanced research. He previously devised health and medical content for Colgate, Dove, Pfizer, Sharecare, Walgreens, and more. Jefferson has spoken about celiac disease to the media, including an appearance on the KQED radio show Forum, and is the editor of numerous books, including "Cereal Killers" by Scott Adams and Ron Hoggan, Ed.D.

    >VIEW ALL ARTICLES BY JEFFERSON ADAMS

     


  • Celiac.com Sponsor (A17):
    Celiac.com Sponsor (A17):





    Celiac.com Sponsors (A17-M):




  • Related Articles

    Michelle Melin-Rogovin
    At the University of Chicago Celiac Disease Program, women with celiac disease who have recently become pregnant often contact us. Remarkably, the questions we receive from these women seldom stray from one issue, that is, whether or not to maintain a gluten-free diet while pregnant. Most women mistakenly believe that the gluten-free diet will deprive their developing fetus with the nutrients it needs, and hurt the growing baby. In fact, for a pregnant woman with celiac disease, remaining ON the gluten-free diet is the best and only option for the health of mother and child. The gluten-free diet provides pregnant women and their babies with all of the nutrients they need to grow and be healthy.
    Fortunately, for all concerned, there have been excellent research studies on fertility...


    Jefferson Adams
    Celiac.com 06/20/2011 - A team of researchers set out to assess menopause-associated disorders and fertile life span in women with untreated celiac disease compared to those who followed a long-term gluten-free diet.
    The research team included Antonella Santonicola, MD, Paola Iovino, MD, Carmelina Cappello, MD, Pietro Capone, MD, Paolo Andreozzi, MD, and Carolina Ciacci, MD.
    For their study, the team recruited 33 post-menopausal women with untreated celiac disease, 25 celiac women who had followed a gluten-free diet for at least ten years before menopause, and 45 healthy volunteers as a control group.
    The team used the Menopause Rating Scale questionnaire to gather information on menopause-associated disorders among study participants. They also used the International Physical...


    Jefferson Adams
    Celiac.com 09/30/2011 - A new study indicates that women who suffer unexplained infertility suffer higher rates of undiagnosed celiac disease than those who do not experience unexplained infertility.
    The study appeared in the May-June issue of the Journal of Reproductive Medicine.
    Using serologic screening for celiac disease as well as routine infertility testing, Janet M. Choi, M.D., of Columbia University in New York City, led a study team that included B. Lebwohl, J. Wang, S. K. Lee, J. A. Murray, M. V. Sauer and P. H. R. Green.
    Together, they assessed 191 women with infertility. The researchers confirmed four women with positive serum test results to have celiac disease. That's 2.1 percent of the 188 patients who completed testing. The women received nutritional counseling...


    Jefferson Adams
    Celiac.com 03/04/2015 - Women with infertility face higher rates of celiac disease, according to a recent data analysis.
    Until now, data connecting celiac disease and infertility has been contradictory. There are currently no recommendations regarding celiac disease screening in female patients with infertility.
    A research team recently conducted a meta-analysis to find out whether women with infertility have a higher risk for celiac disease. The team included Prashant Singh MBBS; Shubhangi Arora MBBS; Suman Lal MD; Tor A. Strand MD, PhD; and Govind K. Makharia MD, DM, DNB, MNAMS.
    To source information for their analysis, the team performed a literature search using the MeSH keywords "celiac disease," "gluten," and "infertility." They based celiac diagnosis on positive patient...


  • Recent Activity

    1. - Hannah24 replied to Hannah24's topic in Celiac Disease Pre-Diagnosis, Testing & Symptoms
      7

      Negative Test but I have All the Symptoms!

    2. - Hannah24 replied to Hannah24's topic in Celiac Disease Pre-Diagnosis, Testing & Symptoms
      7

      Negative Test but I have All the Symptoms!

    3. - trents replied to Linedancegal's topic in Introduce Yourself / Share Stuff
      4

      25 year biopsy confirmed/ate pizza with no ill effects?

    4. - Moodiefoodie replied to Moodiefoodie's topic in Related Issues & Disorders
      2

      Joint swelling when ill even on gluten-free diet

    5. - knitty kitty replied to Holly15892's topic in Post Diagnosis, Recovery & Treatment of Celiac Disease
      7

      Growth spurt after diagnosis in adulthood


  • Celiac.com Sponsor (A19):



  • Member Statistics

    • Total Members
      120,466
    • Most Online (within 30 mins)
      7,748

    CtoThaE
    Newest Member
    CtoThaE
    Joined

  • Celiac.com Sponsor (A20):


  • Forum Statistics

    • Total Topics
      120.2k
    • Total Posts
      1m

  • Celiac.com Sponsor (A22):





  • Celiac.com Sponsor (A21):



  • Popular Now

    • Linedancegal
    • Hannah24
      7
    • jessiemariecar
    • Rhonda H
    • HayleyC123
  • Popular Articles

    • Scott Adams
    • Scott Adams
    • Scott Adams
    • Scott Adams
    • Scott Adams
  • Upcoming Events

×
×
  • Create New...