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Prevalence of Celiac Disease in the United States is Found to be 1 in 133
http://www.celiac.com/articles/647/1/Prevalence-of-Celiac-Disease-in-the-United-States-is-Found-to-be-1-in-133/Page1.html
Scott Adams

In 1994 I was diagnosed with celiac disease, which led me to create Celiac.com in 1995. I created this site for a single purpose: To help as many people as possible with celiac disease get diagnosed so they can begin to live happy, healthy gluten-free lives. Celiac.com was the first site on the Internet dedicated solely to celiac disease. In 1998 I created The Gluten-Free Mall, Your Special Diet Superstore!, and I am the co-author of the book Cereal Killers, and founder and publisher of Journal of Gluten Sensitivity.

 
By Scott Adams
Published on 02/13/2003
 
Celiac.com 2/13/2003 - According to a recently published large-scale multi-year and multi-center s

Celiac.com 2/13/2003 - According to a recently published large-scale multi-year and multi-center study, 1 in 133, or a total of 2,131,019 Americans have celiac disease. Alessio Fasano, MD, et. al., and colleagues screened 13,145 subjects using serum antigliadin antibodies and anti–endomysial antibodies (EMA). Those who had positive EMA results were screened again for human tissue transglutaminase IgA antibodies and CD-associated human leukocyte antigen DQ2/DQ8 haplotypes, and when possible, intestinal biopsies were also given. Additionally, for those with biopsy-proven celiac disease, 4,508 first-degree relatives and 1,275 second-degree relatives were also screened for the disease. A total of 3,236 symptomatic patients and 4,126 not-at-risk individuals were screened.

The study determined the following:

Group Prevalence
First degree relatives 1 in 22
Second-degree relatives 1 in 39
Symptomatic patients 1 in 56
Not-at-risk individuals (overall prevalence) 1 in 133

These results are much higher than previous studies have found, and they indicate that celiac disease is perhaps the most common genetic disorder in the United States, as well as one of the most poorly diagnosed diseases.

February 10, 2003 edition of Archives of Internal Medicine