Detecting heightened levels immune reactions to antigen(s) in food is important because scientists have credible reports of certain health disturbances, such as celiac disease, and some pre-malignant conditions, such as monoclonal gammopathy of undetermined significance (MGUS), disappearing under a regimen of appropriate food restriction diets.

Fibroblasts are one of the most important components in inflammation and tissue remodeling process, and are thought to be involved in the pathogenesis of autoimmune disorders such as celiac disease.

Specialty pharmaceutical and diagnostic company, Prometheus Laboratories Inc., announced results from two recent studies concerning the use of serologic testing to predict inflammatory bowel disease (IBD).

According to the results of a recent study, complete recovery of intestinal mucosa occurs very rarely in patients with celiac disease, despite adherence to a gluten-free diet.

In a medical first, researchers at UCLA have made a connection between intestinal inflammation and systemic chromosome damage in mice, a discovery that may pave the way for early identification and treatment of human inflammatory disorders, some of which raise the risk for various kinds of cancer, according a study published in Cancer Research.

Researchers have found a significant correlation between antibodies to the flagellin CBir1 and HLA haplotypes DQ2.5 and DQ8, an important serologic marker for the detection of Crohn's disease, and particular genetic markers in patients at risk for celiac disease.

Results of a recent small population study done in Spain suggest that a gluten-free diet may change gut bacteria balance by decreasing beneficial bacteria and increasing detrimental bacteria. But how reliable is the data?

Fatty acid binding proteins (FABPs) are one of the tools currently of interest to celiac researchers looking into non-invasive techniques for assessing of intestinal damage in celiac patients.

People with clinical irritable bowel syndrome (IBS) suffer from biopsy-proven celiac disease at rates that are more than four times higher than in non-IBS control subjects, according to the results of a recent systematic review and meta-analysis conducted by Alexander C. Ford, MBChB, MD, MRCP, from Health Sciences Centre, McMaster University, Hamilton, Ontario, Canada, and colleagues.

Not all gluten is equally offensive to celiacs, and some may be both well tolerated and useful for making better bread...