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Celiac Disease & Gluten Intolerance Research

This category contains summaries of research articles that deal strictly with scientific research publications on celiac disease. Most of these research summaries contain the original source of the publication.

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    Lab mice are proving helpful in the search for a cure to celiac disease. Photo: National Cancer Institute

    How come only 2% to 5% of genetically susceptible individuals develop celiac disease? Gut microbes may be the key.



    Photo: CC--Derek Gavey

    Does a lone protein in the gut trigger the inflammation and discomfort associated with gluten-sensitivity in people without celiac disease?



    Latest study says celiac kids don't need follow-up blood work. Photo: CC--Randen Pederson

    Laboratory tests for hemoglobin, ferritin, calcium, folate, vitamin B12, vitamin D, and thyroid function are regularly ordered in children with celiac disease, despite sufficient evidence for their necessity. To determine the frequency of nutritional deficiencies and levels of thyroid dysfunction in children with celiac disease, researches conducted a study that examined children before and after the initiation of a gluten-free diet.



    Photo: CC-- Sam Howzit

    Could gluten immunogenic peptides tell doctors how closely you've been following a gluten-free diet, and how well your gut is healing?



    Gluten introduction before 2 months increases celiac risk in susceptible kids. Photo: CC--Jason Trommeter

    Recently, several studies have set out to determine how intake of gluten during infancy influences later risk of celiac disease.



    Photo: CC--Dean Hochman

    A new study by researchers in Italy shows that only a minority of patients who meet clinical criteria for non-celiac gluten sensitivity actually show symptoms when exposed to gluten in a controlled gluten challenge. Why is that?



    Image: CC--Hobvias Sudoneighm

    Has a Canadian researcher discovered a big clue toward preventing celiac disease?



    Photo: CC- Wendell Oaskay

    A new study clarifies the celiac risk for close relatives of people with the disease.



    Can researchers pin down non-celiac gluten-sensitivity? Photo: CC--Bilal Kamoon

    If you thought celiac disease was slippery, try studying non-celiac gluten sensitivity.



    Daisy petals await decision-making. Photo: CC--Mint Candies

    Can mass screening for celiac disease help enough people, and improve enough lives to justify the cost and effort?



    Image: CC--Valerie Everett

    A research team recently conducted an analysis of the relationship between seronegative celiac disease (SNCD) and immunoglobulin deficiencies.



    Can anti-gluten enzymes help people with celiac disease? Image: Tolerase--DSM, inc.

    According to the latest press release, aspergillus niger prolyl endoprotease (AN-PEP) efficiently degrades gluten molecules into non-immunogenic peptides. But so what?



    Butterfly in the Argentine jungle. Photo: CC--Beatrice Murch

    What can an isolated tribe of indigenous South Americans who have only recently begun eating wheat tell researchers about celiac disease?



    Photo: CC--Arjan Richter

    A research team recently looked at the prevalence of autoimmune diseases among patients with non-celiac wheat sensitivity (NCWS), and investigated whether they carry antinuclear antibodies (ANA).



    Kids picking flowers. Photo: CC-- Peter Schultz

    A team of researchers recently conducted an inverse χ2 meta-analysis across ten pediatric-age-of-onset autoimmune diseases.



    Photo: CC--NIAID

    People with celiac disease have slightly higher risk for contracting pneumonia, especially in the first year after diagnosis.



    Eosinophils in the peripheral blood of a patient with idiopathic eosinophilia. Image: Wikimedia Commons--Ed Uthman, MD.

    Some researchers and clinicians suspect a connection between eosinophilic esophagitis (EoE) and celiac disease, but prior studies have shown conflicting results.



    Champagne toast! Photo: CC--Ryan Hyde

    For the first time since it was described and named by 1st century Greek physician Aretaeus of Cappadocia, first linked to wheat in the 1940's, and specifically linked to gluten in 1952, scientists have discovered the cause of celiac disease.



    Electron microscope image of a healthy human T cell. Image: Wikimedia Commons: NIAID/NIH

    Italian researcher Giuseppe Mazzarella offers an examination of the role of effector and suppressor T cells in celiac.



    Thumbs up? Photo: CC--Paul

    The presence of specific human leukocyte antigen-DQ2 and DQ8 seems to be necessary for celiac disease development, but its usefulness for screening is still uncertain.


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