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Celiac Disease & Gluten Intolerance Research

This category contains summaries of research articles that deal strictly with scientific research publications on celiac disease. Most of these research summaries contain the original source of the publication.

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    Photo: CC--Miles Goodhew

    People with potential celiac disease have blood and genetic markers for celiac disease, but show little or no damage to the small intestinal mucosa. Do they always need a gluten-free diet?

    Photo: CC--Money Images

    Does the preferential xxpression of HLA-DQ2.5 Genes in celiac disease impact T cell response?

    How useful is celiac disease without biopsy? Photo: CC--Military Health

    Considering the new ESPGHAN and BSPGHAN guidelines, how useful is celiac diagnosis without biopsy?

    Photo: CC--foodcraftlab

    Can locally formulated gluten-free flour improve the dietary pattern of Pakistani celiac patients?

    Can high definition increase the detection of celiac disease during routine endoscopy? Photo:

    Even with endoscopies, physicians can still miss some cases of celiac disease. A team of researchers recently set out to determine if I-Scan, or virtual chromo-endoscopy, could improve sensitivity of endoscopy to detect markers of villous atrophy in patients with celiac disease.

    Image: CC--Mehmet Pinarci

    The development of celiac disease has been tied to polymorphisms in the regulator of G-protein signaling 1 (RGS1) and interleukin-12 A (IL12A) genes, but existing data are unclear and contradictory.

    Image: CC--AndreaLaurel

    Growing evidence suggests that long noncoding RNAs (lncRNAs) play an important role in gene expression, especially that which influences inflammation.

    What makes ultra-short celiac disease different than regular celiac disease? Photo: CC--George

    What's ultra-short celiac disease, and what sets it apart from standard celiac disease?

    Photo: CC--Cupcake Kitschen

    New guidelines reverse previous recommendations on infant gluten introduction to prevent celiac disease. What's going on?

    Photo: CC--Amblin

    Can predictive values of transglutaminase (tTG) antibodies help diagnose celiac disease in kids, without the need for a biopsy?

    Photo: CC--Roman Boed

    Dutch researchers recently completed a large study of celiac patients based on symptoms, co-occurrence of immune mediated diseases, and malignancies.

    Photo: CC--Nicolas Buffler

    A team of researchers recently completed the first extensive study comparing gene expression in children and adults with celiac disease, and found some key differences between the two groups.

    Though painted by John Singer Sargent, Mary Turner Austin is not known to have Turner Syndrome or celiac disease. Photo: CC--Freeparking

    Women and girls who have Turner syndrome are significantly more likely to have celiac disease than those without the sex chromosome anomaly, according to a new study by Scandinavian researchers.

    Lab mice are proving helpful in the search for a cure to celiac disease. Photo: National Cancer Institute

    How come only 2% to 5% of genetically susceptible individuals develop celiac disease? Gut microbes may be the key.

    Photo: CC--Derek Gavey

    Does a lone protein in the gut trigger the inflammation and discomfort associated with gluten-sensitivity in people without celiac disease?

    Latest study says celiac kids don't need follow-up blood work. Photo: CC--Randen Pederson

    Laboratory tests for hemoglobin, ferritin, calcium, folate, vitamin B12, vitamin D, and thyroid function are regularly ordered in children with celiac disease, despite sufficient evidence for their necessity. To determine the frequency of nutritional deficiencies and levels of thyroid dysfunction in children with celiac disease, researches conducted a study that examined children before and after the initiation of a gluten-free diet.

    Photo: CC-- Sam Howzit

    Could gluten immunogenic peptides tell doctors how closely you've been following a gluten-free diet, and how well your gut is healing?

    Gluten introduction before 2 months increases celiac risk in susceptible kids. Photo: CC--Jason Trommeter

    Recently, several studies have set out to determine how intake of gluten during infancy influences later risk of celiac disease.

    Photo: CC--Dean Hochman

    A new study by researchers in Italy shows that only a minority of patients who meet clinical criteria for non-celiac gluten sensitivity actually show symptoms when exposed to gluten in a controlled gluten challenge. Why is that?

    Image: CC--Hobvias Sudoneighm

    Has a Canadian researcher discovered a big clue toward preventing celiac disease?

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