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Celiac Disease & Gluten Intolerance Research

This category contains summaries of research articles that deal strictly with scientific research publications on celiac disease. Most of these research summaries contain the original source of the publication.

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    Australian food manufacturers and retailers are pushing the government agency that regulates gluten-free food to allow gluten to be included in foods labeled ''gluten-free.''

    Photo: CC-- Ivana Visilij

    In an effort to find a way other than these invasive methods to distinguish between uncomplicated and complicated forms of celiac disease, a research team set out to study serum parameters in the spectrum of celiac disease

    Photo: CC-- Allen Gathman

    Researchers have completed a genetic study of six autoimmune diseases, including diabetes, the largest such study of human disease genetics to date.

    Photo: CC--withassociates

    Potential celiac disease (PCD) is a type of celiac disease marked by positive endomysial/tissue transglutaminase antibodies and a preserved duodenal mucosa despite a gluten-containing diet (GCD). PCD can turn into active celiac disease, but very little is currently known about what causes that to happen.

    Photo: CC--@alviseni

    Hoping to develop a vaccine that will allow patients with celiac disease to safely eat gluten, researchers are busily exploring the possibilities offered therapeutic vaccines, known as antigen-specific immunotherapy.

    Photo: The Everlasting Fallout

    To investigate the prevalence of human leukocyte antigen (HLA) DQ2/8 alleles in Southern Italians with liver and gastrointestinal (GI) diseases outside of celiac disease, a team of researchers recently looked at human leukocyte antigen DQ2/8 prevalence in non-celiac patients with gastrointestinal diseases.

    Photo: CC--Bettina N.

    Researchers have known for some time that immunoglobulin G antibodies against deamidated gliadin peptides are about as accurate as tissue transglutaminase and endomysium autoantibodies in diagnosing celiac disease in adults. However, not much is known about their predictive value in infants with a suspected gluten enteropathy.

    Photo: CC--alegrya

    A number of studies have indicated that people with celiac disease have an inadequate response to hepatitis B vaccination. In an effort to better understand the issue, a team of researchers assessed hepatitis B vaccination response in relation to gluten exposure status in patients with celiac disease.

    Photo: CC--stevendepolo

    Intestinal absorption capacity is currently regarded as the best way to assess overall digestive intestinal function. Earlier reference values for intestinal function in healthy Dutch adults were based on a study that was conducted in an inpatient metabolic unit setting in a relatively small series.

    Photo: CC--kenteengardin

    Previous studies have shown an immunologic response primarily directed against transglutaminase (TG)6 in patients with gluten ataxia (GA). A team of researchers set out to see if Transglutaminase 6 antibodies could be helpful in the diagnosis of gluten ataxia.

    Photo: CC--mediajon

    A team of researchers recently set out to test determine if an interactive online intervention might help to improve gluten free diet adherence in adults with celiac disease.

    Photo: CC--nicola

    A team of researchers recently set out to determine how microbial fermentation with lactic acid bacteria might be used to make better gluten-free products.

    Photo: CC--IceSabre

    A team of researchers recently set out to determine whether IEL parameters have any connection with mortality and morbidity in cases of refractory celiac disease.

    In this photo, hepatitis B attacks cells. Photo: CC--ajc1

    A team of researchers recently took a look at how well the hepatitis B vaccine protected people with celiac disease over time, and how well they responded to a vaccine booster.

    Photo: CC-- Capt. Kodak

    There haven't been many studies that evaluate the usefulness of capsule endoscopy in equivocal celiac disease. A team of researchers recently set out to conduct an evaluation of capsule endoscopy in adult celiac disease...

    Photo: CC--greenflames09

    More and more, research is showing that celiac disease may have a variety of different clinical presentations. A team of researchers recently used data from Italy, Romania and Iran to explore rates of gastrointestinal and non-gastrointestinal symptoms in patients with celiac disease.

    Photo: CC--Kezze

    Enterocyte damage is one of the common features of celiac disease, and often results in malabsorption. Presently, doctors don't know very much about the recovery of enterocyte damage and its clinical consequences. Serum intestinal fatty acid binding protein (I-FABP) is a marker that allows researchers to study enterocyte damage.

    Photo: CC--benchilada

    People with celiac disease all have some degree of damage to the small intestinal mucosa, ranging from lymphocytic duodenosis with normal villous structure to severe villous atrophy.

    Photo: CC--AJC1

    To determine if the probiotic Bifidobacterium natren life start (NLS) strain might affect the treatment and clinical features of patients with untreated celiac disease, a team of researchers recently conducted an exploratory, randomized, double-blind, placebo-controlled study on the effects of Bifidobacterium infantis natren life start super strain in active celiac disease.

    Photo: CC--winnifredxoxo

    People with celiac disease must follow a gluten-free diet if they want to remain healthy, but a 200-patient study conducted by Alvine Pharmaceuticals show that 90 percent of celiac patients who followed a gluten-free diet still reported symptoms of the disease.

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