Rates of celiac disease are four times higher today than they were just fifty years ago, according to the results of a new study by scientists at the Mayo clinic. In addition, the study showed that people with undiagnosed celiac disease died at rates four times higher than non-celiacs over the 45 year follow-up period.

Detecting heightened levels immune reactions to antigen(s) in food is important because scientists have credible reports of certain health disturbances, such as celiac disease, and some pre-malignant conditions, such as monoclonal gammopathy of undetermined significance (MGUS), disappearing under a regimen of appropriate food restriction diets.

Fibroblasts are one of the most important components in inflammation and tissue remodeling process, and are thought to be involved in the pathogenesis of autoimmune disorders such as celiac disease.

According to the results of a recent study, complete recovery of intestinal mucosa occurs very rarely in patients with celiac disease, despite adherence to a gluten-free diet.

Researchers have found a significant correlation between antibodies to the flagellin CBir1 and HLA haplotypes DQ2.5 and DQ8, an important serologic marker for the detection of Crohn's disease, and particular genetic markers in patients at risk for celiac disease.

Results of a recent small population study done in Spain suggest that a gluten-free diet may change gut bacteria balance by decreasing beneficial bacteria and increasing detrimental bacteria. But how reliable is the data?

Recently, the British Journal of Nutrition reported that following a gluten-free diet may be detrimental to gut health, which may also affect immune health. This article discusses the signs of decreased gut health and what steps to take to make improvements.

Celiac disease is an autoimmune disorder that is triggered by gluten in the bloodstream, and is becoming increasingly common. Previously considered quite rare, it is now estimated to occur in 1 in 100-150 people in all societies except Japan. Physical activity fights against some of the lasting symptoms of celiac disease, but some of the symptoms inhibit physical activity.

Fatty acid binding proteins (FABPs) are one of the tools currently of interest to celiac researchers looking into non-invasive techniques for assessing of intestinal damage in celiac patients.

People with clinical irritable bowel syndrome (IBS) suffer from biopsy-proven celiac disease at rates that are more than four times higher than in non-IBS control subjects, according to the results of a recent systematic review and meta-analysis conducted by Alexander C. Ford, MBChB, MD, MRCP, from Health Sciences Centre, McMaster University, Hamilton, Ontario, Canada, and colleagues.