The recent discovery that people with celiac disease harbor antibodies that are specific for deamidated gliadin peptides (DGP), which are the product of tTG binding to gliadin peptides, offers a chance to examine the connection between the production of anti-tTG IgA and the antibodies against DGP in celiac patients.

A team of Swiss researchers recently set out to examine the nature of T cell-mediated immuno-regulation in the gastrointestinal tract. The research team was made up of doctors L. Saurer and C. Mueller of the Institute of Pathology at the University of Bern in Switzerland.

Numerate Inc., a biotechnology company leveraging a novel drug engineering process to design lead-stage drug compounds, announced today it has received a Phase 1 grant from the National Institute of Diabetes and Digestive and Kidney Diseases of the National Institutes of Health (NIH).

A recent study confirms that celiac disease affects adults with Turner Syndrome at rates of up to 5 times those of the general population.

For the first time, researchers have shown that B. lactis probiotic bacteria are capable of shielding epithelial cells from cellular damage caused by gliadin exposure, and that they may play a valuable role in as a dietary supplement to guard against any silent damage associated with accidental gluten-contamination in celiac disease.

In a development that could benefit people with celiac disease and gluten intolerance, a team of researchers based in Spain and the U.K. has developed a faster, easier way to test food products for the protein that triggers the adverse reactions associated with celiac disease.

Managing celiac disease can be challenging in the best of circumstances, so imagine the frustration of experiencing on-going gastro-intestinal symptoms even while following a gluten free diet. Such frustration is increasingly common among people with celiac disease.

A team of researchers based in the Netherlands recently discovered that certain antibodies, those called monoclonal antibodies, react to the presence of gluten proteins in much the same way as human T cells, and that these antibodies offer promise for reliably detecting the presence of wheat, barley, rye, and even oat gluten in food products.

A team of Finnish researchers announced that they have found high rates of undetected celiac disease in elderly populations. They have also noted that a significant number of those older people diagnosed with celiac disease showed only minor symptoms.

Cytokines are regulatory proteins that act as mediators in the generation of an immune response. Interleukin 21 (IL-21) is on such cytokine. A team of Italian and British researchers recently evaluated the production of IL-21 in the intestinal mucosa of patients with untreated celiac disease.