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<channel><title><![CDATA[Celiac Disease & Gluten-free Diet Information at Celiac.com - Comments for article: 400% Increase in Risk of Death for Undiagnosed Celiacs]]></title><link>http://www.celiac.com</link><description /><language>en-us</language><copyright><![CDATA[http://www.celiac.com]]></copyright><generator>N/A</generator><webMaster>scott@celiac.com</webMaster><lastBuildDate>Tue, 21 May 2013 07:06:04 PDT</lastBuildDate><ttl>20</ttl><item><title><![CDATA[Comment #1]]></title><link>http://www.celiac.com/articles/21806/1/400-Increase-in-Risk-of-Death-for-Undiagnosed-Celiacs/Page1.html#Comment3706</link><description><![CDATA[Yeah but I'm already at a 100% risk of death so this data seems kind of irrelevant.<br/><br/>
(Comment posted by Todd at 4:28 pm, Sun 3rd May 2009)]]></description><author>no@spam.com (Todd)</author><pubDate><![CDATA[Sun, 03 May 2009 16:28:23 PDT]]></pubDate><guid isPermaLink="true">http://www.celiac.com/articles/21806/1/400-Increase-in-Risk-of-Death-for-Undiagnosed-Celiacs/Page1.html#Comment3706</guid></item><item><title><![CDATA[Comment #2]]></title><link>http://www.celiac.com/articles/21806/1/400-Increase-in-Risk-of-Death-for-Undiagnosed-Celiacs/Page1.html#Comment3735</link><description><![CDATA[Excellent article, though apparently some of the readers don't understand statistics...<br/><br/>
(Comment posted by Fred Martin at 3:43 pm, Thu 7th May 2009)]]></description><author>no@spam.com (Fred Martin)</author><pubDate><![CDATA[Thu, 07 May 2009 15:43:20 PDT]]></pubDate><guid isPermaLink="true">http://www.celiac.com/articles/21806/1/400-Increase-in-Risk-of-Death-for-Undiagnosed-Celiacs/Page1.html#Comment3735</guid></item><item><title><![CDATA[Comment #3]]></title><link>http://www.celiac.com/articles/21806/1/400-Increase-in-Risk-of-Death-for-Undiagnosed-Celiacs/Page1.html#Comment3873</link><description><![CDATA[The key data point from the study is here:

'Of 9,133 Air Force subjects, 14 had undiagnosed celiac disease--a rate of 0.2%. In that cohort, persons with undiagnosed celiac disease had higher mortality rates across the board than those who had tested negative (hazard ratio=3.9; 95% CI, 2.0-7.5; P <.001). '
The researchers followed the group over a 45 year span and in every case, they showed earlier mortality than their non-celiac counterparts. They also corroborated and adjusted their numbers in accordance with a related study:

'In the case of the Minnesota cohorts, the team found undiagnosed celiac disease in 68 persons with similar age at sampling (0.9%), and 46 persons with similar years of birth (0.8%). These recent cohorts showed rates of undiagnosed celiac disease that were 4.5-times and 4-times greater than the Air Force cohort (both P=.0001).'

The reasons for increased mortality rates are likely due to the degenerative effects of undiagnosed celiac disease--excess cancers, nutritional deficiencies, other associated conditions, etc. The study didn't get into the 'Whys,' just the fact that mortality rates are higher--meaning undiagnosed celiacs die younger than those without celiac disease (specifically, if you have undiagnosed celiac disease, over the 45 year period in question, you would die earlier than 400 comparable people without celiac disease 100% of the time--follow? So if you compared 10 celiacs to 4000 non-celiacs, or 100 celiacs to 40000 non-celiacs, the celiacs would ALL die before the non-celiacs--for whatever reasons).

They also note that with increased diagnosis and treatment trends, that this reality is changing. Fewer people will go through life with undiagnosed celiac disease, and so more people will live longer than they would have otherwise.


-J.A.<br/><br/>
(Comment posted by Jefferson Adams at 12:07 pm, Fri 5th Jun 2009)]]></description><author>no@spam.com (Jefferson Adams)</author><pubDate><![CDATA[Fri, 05 Jun 2009 12:07:13 PDT]]></pubDate><guid isPermaLink="true">http://www.celiac.com/articles/21806/1/400-Increase-in-Risk-of-Death-for-Undiagnosed-Celiacs/Page1.html#Comment3873</guid></item></channel></rss>