Cancer Risk 47% Lower--risk Of Heart Disease Is 48% Higher In Those With Celiac Disease
Celiac Disease Articles
Here is the abstract of the study:
High Mortality in Ischaemic Heart Disease in Patients with Celiac Disease
Department of Internal Medicine, Skovde Hospital, Skovde, Sweden
INTRODUCTION: "Previous reports about increased risks of malignancies and mortality in patients with celiac disease have been criticized as skewed by selection bias, because they emanate from referral centers. Recent register based studies indicate lower risks, but are contingent on complete registration."
AIMS & METHODS: "Our aim was to perform a retrospective cohort study of all celiac disease patients residing in two Swedish counties and evaluate the risks of malignancies and excess mortality. All diagnosed celiac disease patients 15 years or older who were residents of the Örebro and Linköping hospitals primary catchment areas on 31 Dec. 1986 were identified and followed up for at least 15 years. All celiac disease patients were checked against the Swedish hospital inpatient register. Standardized mortality ratios (SMR) and standard incidence ratios of cancer (SIR) were calculated."
RESULTS: "There was a 47 percent lower risk of all malignancies in our total celiac population SIR=0.53 (95% C.I. 0.31-0.83) as compared with the general population. Total mortality was increased by 38% (SMR 1.38, 95% C.I. 1.08-1.75) as compared with the general population and was most pronounced in patients over 65 years (SMR 1.46).This was mainly explained by a 48% increased death rate in ischaemic heart disease, significant in patients over 65 years (SMR 1.58, 95% C.I. 1.00-2.06). "
CONCLUSION: "In a population based setting including all patients with celiac disease, there was no increased risk of malignancies. However, this study confirms an excess mortality risk, which appears to be attributable to ischaemic heart disease mainly in patients over 65 years of age."
Copyright © 2006 Scott Adams. All rights reserved worldwide.