This Celiac.com FAQ on celiac disease will guide you to all of the basic information you will need to know about the disease, its diagnosis, testing methods, a gluten-free diet, etc. Subscribe to FREE Celiac.com email alerts What are the major symptoms of celiac disease? Celiac Disease SymptomsWhat testing is available for celiac disease? - list blood tests, endo with biopsy, genetic test and enterolab (not diagnostic) Celiac Disease ScreeningInterpretation of Celiac Disease Blood Test ResultsCan I be tested even though I am eating gluten free? How long must gluten be taken for the serological tests to be meaningful?The Gluten-Free Diet 101 - A Beginner's Guide to Going Gluten-FreeIs celiac inherited? Should my children be tested? Ten Facts About Celiac Disease Genetic TestingIs there a link between celiac and other autoimmune diseases? Celiac Disease Research: Associated Diseases and DisordersIs there a list of gluten foods to avoid? Unsafe Gluten-Free Food List (Unsafe Ingredients)Is there a list of gluten free foods? Safe Gluten-Free Food List (Safe Ingredients)Gluten-Free Alcoholic BeveragesDistilled Spirits (Grain Alcohols) and Vinegar: Are they Gluten-Free?Where does gluten hide? Additional Things to Beware of to Maintain a 100% Gluten-Free DietFree recipes: Gluten-Free RecipesWhere can I buy gluten-free stuff? Support this site by shopping at The Celiac.com Store.For Additional Information: Subscribe to: Journal of Gluten Sensitivity
I believe the latest status on those enzymes were pending clinical trials. I guess they just finished those trials only a few days ago. http://clinicaltrials.gov/ct2/show/NCT00810654
I guess it is a waiting game to see what the results show.
Preliminary studies however show positive results http://www.ncbi.nlm.nih.gov/sites/entrez
Not saying that this is a cure for celiacs (or maybe it is) but it seems like within a few more years they may be able to find something that is even more effective. There is another company that is currently working on using the strepto lactis bacteria to genetically modify the bacteria's DNA and split human sequence into it that allows for the digestion of gluten and has a protective measure on the intestines. It would essentially be a GMO probiotic. They are also working on this. I find this stuff fascinating!
I'm new and im the process of getting tested for a myriad of issues. And symptoms wise i definitely do worse intestinally when i eat gluten. but sometimes when i have crackers it doesnt really bother me. Bread or pasta does however. I was wondering if someone could tell me what the difference between gluten intolerance/sensitivity is with full blown celiac's disease? Are they the same? I looked online and they always pair the two together but from what i understand there are people that do not have celiac disease but still cannot eat gluten because it causes problems. How do you know which one you have? blood tests and biopsy? symptoms wise?
Secondly, i did a search but the most recent thread i found regarding this matter was from 08. In 2007, there was an article released describing an enzyme that was 60 fold quicker in breaking down gluten than a previous enzyme that was researched and it was done so with high stability and in the stomach pH. It said that gluten is broken down in 4 minutes in the acidic pH. The enzyme is called AN-PEP, which is different than the DPP-IV found in most gluten enzymes such as Glutenease by enzymedica. Currently i only found one product that has it called Gluten guard by trimedica.
Obviously staying gluten free would be the most ideal way but for those who are gluten sensitive, it may help?
I guess you are right, nobody knows! What I was wondering is when they do a biopsy and see the flatten villi in the small intestine, how do they know whether it is from celiac and gluten damage or from other food allergy inflammations?
I guess ive made a bit of a mess. I'm on a relaxed gluten free diet. 90% gluten free but once in a while i'll eat some crackers or something that might contain trace amounts of gluten. I never eat actual wheat rye barley or oat products though. If i want an accurate test, i will have to start eating gluten like crazy for weeks i think, to get an accurate reading. But that means, worsening my health and intestine inflammation ive worked hard to try and heal. The other method is to just go completely gluten free but that means i'll never have a diagnosis. Not a good place to be in.
I also thought about just getting the tTG antibody checked anyway but i'm IgA deficient so it's not going to be accurate anyway!
Currently I am awaiting a food allergy test IgG that will show gluten and wheat allergies. If it does not come up or if something else comes up that makes more sense, I will know more.
Where did everyone learn to go gluten free? I don't even know what has gluten .. EVERYTHING has gluten in it. Who knew that "modified food starch" is gluten. Geez, how do you eat out ever, or do anything social? Don't mistake what i'm saying though, i would rather give up gluten and restaurants and be houseridden any longer!
Thank you for the detailed explanation. I told my doctor that i am SIgA deficient (or was a few months ago) and he still prescribed the tTG IgA. Should i call him and ask to add/change to the IgG instead?
So how do you know whether you have celiac's disease or just a gluten sensitivity because of something like a leaky gut or something? I was reading Enterolab's FAQs and it says that a stool test is the most accurate but they also test for IgA and doesnt mention anything about being IgA deficient.
Could it be possible to have a gluten IgG allergy but not celiac disease that's causing the gut inflammation?
What i don't understand is, how i developed celiac disease (if i have it) I don't eat anything wheat, rye or barley other than white bread. (not anymore either) My entire family and relatives do not even know what that is, it is unheard of. And symptoms wise, I've had chronic digestion issues for 3 years which is why doctors want to get celiac but they never do it properly NOR do they listen to my symptoms! During the 3 years, I've had "remission" months at a time where i was having gut problems and being completely 100% better with no inflammation and being able to eat anything and even binge drink with no problem/inflammation. I'm being tested for leaky gut so food allergy inflammation might have something to do with it but i'm not sure how celiac or gluten would fit in the picture. Does celiac cause leaky gut? (they say small amount of celiac have IgA deficiency) or does prolonged leaky gut and developing food sensitivities start a reaction to gluten and cause gluten sensitivity?
i'm 23 and i am extremely sick and have 0 diagnosis after $25k in debt after insurance, 20 doctors, specialists all over from UCLA and cedar sinai. I'm currently still working with them to find out what's wrong.
Basically, ONE of the aspects of my health among many, is gastrointestinal problems. I've been dealing with medium inflammation for 3-4 years on and off that would be aggravated with things like alcohol, yeast products, whey protein, etc. But otherwise, i was doing good, normal formed bowel movements on the dot everyday. However after a course of antibiotics and a flareup of bacteria/yeast, i have never been the same. i can't eat anything, ive developed food sensitivities and bloat up after every meal. I get weird dull pains and a sense of fullness in my small intestines.
I have so many question and confusions. I need to be at least functional and walking again agh.
ive had the gliadin ab test done and it was 5. which is low. you need at least 15 to be positive. but my SIgA was deficient.
My doctor wrote me a lab prescription to get tTG Antibody IgA tested but from what i read, that won't be accurate either and can yield false negative because i have iga deficiency.
Should i ask him to also get tTG IgG as well? both? none?
What about ELISA IgG food allergy tests that test your blood IgG and IgE reactions to gluten? Is that useful for celiacs or is that only for gluten allergy/sensitivity type?
I've been on a very relaxed "gluten free" diet ...eating some gluten in crackers but not wheat or any of those types.. will my test be sensitive or do i need to start eating wheat bread for a week before i test?
Is celiac's curable permanently? are there any members (even rarely) that have been cured of celiacs and been able to eat gluten after their gut has healed, etc?
a lot has been running through my mind. any help appreciated. low money and energy. thank you