A couple of years ago when Armour was having production problems my doctor recommended compounded pig thyroid available at a local pharmacy. I started on that and noticed gluten issues - until I had the pharmacy switch from gelatin capsules to cellulose ones. I have done better, both thyroid- and gluten-wise, on compounded pig thyroid in cellulose capsules than anything else I have tried (Synthroid, levothyroxine (sp?), Armour thyroid). The major drawback is the cost - significantly higher that the other options; insurance may or may not cover, but will probably consider it a "premium" prescription which carries a higher co-pay. I started back on Armour again for the first time in a couple of years just a couple of weeks ago because of the cost differential (about $25-30 more a month), but am noticing possible gluten related issues, so, just this morning decided to go back on the compounded pig thyroid.