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Okay, so I'm answering my own question here -- I just found this on the National Foundation for Celiac Awareness site:
Does having non-celiac gluten sensitivity increase your risk of developing other autoimmune disorders?'
Dr. Leffler: We don’t know 100%, but I would say that the fact that it doesn’t appear to share the genetic predisposition for celiac disease (that HLA-DQ2 and DQ8 which seem to be autoimmune predisposing), suggests that [non-celiac gluten sensitivity] is not likely to be as associated, if at all, with other autoimmune conditions. And I think, again, there’s been very little work done in this area, but the little work that has been done sort of suggests this as well – that there’s not an increased risk of autoimmune diseases in the non-celiac gluten sensitivity picture, but I think that clearly this is still a work in progress.
[During the webinar, a spot poll revealed that 8% of attendees reported having non-celiac gluten sensitivity and an autoimmune disorder. Dr. Leffler was asked to address this.] Dr. Leffler: Autoimmune conditions of various sorts are pretty common in the general population, thyroid disease being the most common. But if you add them all up, 5-10% of the general population will have some autoimmune disease, so the 8% of people in the audience with non-celiac gluten sensitivity really is about population level.
Maybe this will help answer someone else's question, as well!
Thanks, Maureen. I appreciate your input. I know we're all on our own gluten-free journeys, but so much of our stories overlap, and it helps to hear from others fighting some of the same battles. I've looked at Dr. Osborne's site -- he's in the Houston area, as am I. I'm struggling enough at the moment with avoiding gluten, dairy, and soy. Once I've got those down (and it's getting easier every day), then I'll look at the possibility of sensitiviy to other foods -- and possibly to other grains. Corn may be an issue for me.
I posted a question in another forum, but maybe I'll try again here. Does anyone know if other autoimmune disorders coincide with non celiac gluten intolerance? Or just with Celiac?
I'm really frustrated with how, after doing a search and reading the first thread, I can't go back to the search results and continue. is there a way to do this? When I use the back feature on my browser, it doesn't go back there.
I've seen a lot of information about the connection between celiac disease and other autoimmune diseases. But I was wondering if there is also a connection between non-celiac gluten intolerance (NCGI) and autoimmune diseases?
It's difficult to research this via search engines. Does anyone know?
I really don't know about the complications of having two copies of the DQ2 gene, but can imagine they could be serious. I'm SO glad you have learned this while she's still so young. She's a very lucky little girl to have a mommy that is staying on top of these things and caring so well for her and the rest of her family.
Tough question about what to do next. I guess, in your shoes, i would contact gastroenterologist as soon as he/she is back in the office. Maybe your daughter's test can be scheduled quickly?
I agree ... Treatment is the same. I've already noticed that my reaction to gluten is more severe than before I stopped eating it. At least, I assume it was gluten cross contamination. No more eating out for me for awhile!
It would be nice to know for certain if I actually have celiac disease. But, as I said earlier, I'm not going back on gluten. So, with the immensity of the combined experience, learning, and wisdom here, I wanted your opinions. They're worth more to me than that of most physicians!
I'd like to ask another question. Does the fat malabsorption in the severe range mean that there is villous atrophy/damage? If so, wouldn't this be enough in itself for a diagnosis as long as the malabsorption isn't caused by something else?
I've been lurking here for about a month and finally decided to post. Thinking I may have a problem with gluten sensitivity, I did the Enterolab "poop" test (really gross, but had quite the laugh in the car on the way to UPS, wondering if they would ask me if I wanted to insure the contents! ). Here are my results:
Fecal Anti-gliadin IgA 71 Units
Fecal Anti-casein (cow’s milk) IgA 31 Units
Fecal Anti-ovalbumin (chicken egg) IgA 9 Units
Fecal Anti-soy IgA 13 Units
Because anything over 10 is outside the normal range, I show sensitivities to gluten, casein, and soy.
Then they checked my fat malabsorption: Quantitative Microscopic Fecal Fat Score 1288 Units
Anything over 300 is outside the normal range, with over 1000 being in the severe range. Wow!!
No DQ2 or DQ8, but two gluten sensitivity genes, one of them a DQ7 which has been implicated in a low percentage of celiac cases.
Here's a history of medical problems I've had over the years, many of which I've seen reported as correlaeted with celiac disease::
Bedwetter till age 12 (so were my sister and brother)
Very irregular menstrual cycles
Seborrheic dermatitis (severe) - started with "cradle cap" as an infant
Episodes of tingling and numbness
Obesity since age 9
Frequent eye twitching
Severe hay fever
Diverticulosis with 3 episodes of diverticulitis
Leukocytoclastic vasculitis (also known as cutaneous vasculitis), an autoimmune disorder
Possible Sjogren's - rheumatologist did not test for it, but believes it's likely, although I'm not so sure
I'm thinking I may be one of the few celiac patients without DQ2 or DQ8. I cannot have blood testing done because I've been gluten free and dairy free for about six weeks and have no desire to do a gluten challenge. I am feeling significantly better off gluten -- fibromyalgia pain is essentially gone, knees don't hurt, SD has cleared up, heart palpitations have slowed down, hay fever is reduced, UTI's have decreased, and I've lost about 13 pounds.