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I started Dapsone on 100 or 125 mg daily after severe outbreak in my face, on my legs and arms. Came down to 50 mg daily and Although the doctor adviced (repeatedly) to follow a glutenfree diet, I did not follow any glutenfree diet up till 1 year ago. I've stopped with Dapsone about 6 months ago (wanted to try out if I could do without Dapsone), and have been having small rashes occasionally until 3 weeks ago. At this moment I'm having a severe and unstoppable outbreak on my feet/toes and thus will be restarting on Dapsone asap. I'm convinced in my case stress is definitely a trigger. Went on holiday 5 weeks ago for 2 weeks and by the time I returned home, my rashes had almost completely healed. Anyway, to answer your questions: Do you have new outbreaks while on Dapsone? --> no, only if I forget to take it. 1 forgotten tablet is enough to start itching here and there... Do you feel small bumps under your skin that do not break open? --> no, not that I can remember. If you eat gluten, do you breakout? --> no breakout as long as I'm taking my daily dose of Dapsone. The smallest dose I can take without breakout is 50 mg daily. Do you still have episodes of intense itching? --> not while taking Dapsone. How long did it take for your open lesions to heal? --> Once started with Dapsone, the differeence in 1 week time was phenomenal (my doctor couldn't believe it healed so quickly). I think overall it took 2-3 weeks to heal. The itching stopped within 12-24 hrs. Hope this helps.