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Showing results for tags 'eosinophilic esophagitis'.
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Celiac.com 03/23/2022 - There's not much solid data, and no clear consensus, on the connection between eosinophilic esophagitis and celiac disease. There seems to be no clear pattern to the conditions in which they occur together in patients. A team of researchers recently set out to investigate rates of esophageal eosinophilia and eosinophilic esophagitis in a large group of children with celiac disease, and to prospectively follow the group over an eleven year period. The research team included Fernanda Cristofori; Fulvio Salvatore D’Abramo; Vincenzo Rutigliano; Vanessa Nadia Dargenio; Stefania Castellaneta; Domenico Piscitelli; Davide De Benedittis; Flavia Indrio; Lidia Celeste Raguseo; Michele Barone; and Ruggiero Francavilla. They are variously affiliated with the Interdisciplinary Department of Medicine, Pediatric Section “B. Trambusti”, University of Bari “Aldo Moro” in Bari, Italy; the Department of Emergency and Organ Transplantation, Section of Gastroenterology, University of Bari “Aldo Moro” in Bari, Italy; the Department of Emergency and Organ Transplantation, Section of Pathology, University of Bari “Aldo Moro” in Bari, Italy; the Department of Information Engineering, University of Pisa, Largo L. Lazzarino in Pisa, Italy; and the Department of Medical and Surgical Science, University of Foggia, Viale L. Pinto, 71122 Foggia, Italy. The team used data from a prospective observational study performed between 2008 and 2019. They used ESPGHAN criteria to make celiac disease diagnosis. They sampled at least four esophageal biopsies in patients who underwent endoscopy. The team defined esophageal eosinophilia as at least 15 eosinophils/HPF seen on esophageal biopsy. They diagnosed eosinophilic esophagitis using the International Consensus Diagnostic Criteria for Eosinophilic Esophagitis. The team diagnosed a total of 465 children with celiac disease. A total of three hundred and seventy patients underwent endoscopy, while the team found esophageal biopsies for 313 of those. The rate of esophageal eosinophilia in children with celiac disease was 1.6%. Just a single child was diagnosed with eosinophilic esophagitis, for which the team calculated a prevalence rate of 0.3%. Overall, the team saw eosinophilic esophagitis in celiac patients at a rate at least 6.5 times higher than in the general population. According to the team, eosinophils over 15/HPF do not have a clinical implication or warrant intervention in celiac patients, so they do not recommend esophageal biopsies beyond what may be clinically indicated. This is one of the first studies to put some hard numbers on the connection between eosinophilic esophagitis and celiac disease. The idea that people with celiac disease don't generally need to worry about eosinophilic esophagitis is one less thing to deal with in the often confusing world of living with celiac disease. Read more: Nutrients 2021, 13(11), 3755
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- celiac disease
- eosinophilia
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Celiac.com 10/30/2019 - More and more, doctors are noticing cases of both celiac disease and eosinophilic esophagitis (EoE) in children. A team of researchers recently set out to examine the results of therapeutic dietary treatment in a group of children with celiac disease and eosinophilic esophagitis. The research team included Tiffany Patton; Ankurt Chugh; Leena Padhye; Catherine DeGeeter; and Stefano Guandalini. They are variously affiliated with the Section of Pediatric Gastroenterology, Hepatology, and Nutrition, Comer Children's Hospital, University of Chicago Medical Center, Chicago, IL; the Section of Pediatric Gastroenterology, Hepatology, and Nutrition, Medical College of Wisconsin, Milwaukee, WI; the Division of Allergy and Immunology, Rush University Medical Center, Chicago, IL; and the Section of Pediatric Gastroenterology, Hepatology, and Nutrition, Stead Family Children's Hospital, University of Iowa, Iowa City, IA. For their assessment, the team reviewed patient records obtained from the University of Chicago Celiac Center Database from August 2008 to July 2013. The researchers collected information on children with both celiac disease and eosinophilic esophagitis including age, sex, dates of diagnoses, presenting symptoms, length of symptoms before diagnosis, family and personal history, dietary therapy, and esophageal response to dietary treatment. The team reviewed records of 350 pediatric celiac disease patients. Twenty-two children, or 6.3% had confirmed celiac disease and eosinophilic esophagitis, 17 of those children had repeat biopsies. In four cases, the esophageal eosinophilia cleared up on a strict gluten-free diet, 10 of 17 (59%) needed to eliminate other foods before the problem resolved, 1 of 17 failed to reached histological remission, while there was no follow-up information for 2 of those 17 patients. After symptom improvement, five out of five patients could tolerate soy, three of five could tolerate eggs, three of seven could eat dairy, two out of four could tolerate nuts 2 of 4, and two of four can tolerate fish. This is perhaps the largest pediatric study to examine the histologic aspects of EoE-associated esophageal eosinophilia in response to dietary treatment of pediatric patients with both celiac disease and eosinophilic esophagitis. The results show that most of these patients can tolerate soy, and suggest that making it the first food to be reintroduced, or testing out a soy-inclusive elimination diet could be helpful for those patients. Read more in the Journal of Pediatric Gastroenterology and Nutrition: August 2019.
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Sorry my titles so long but its hard to really shorten that. I'm trying to get advice for family planning, I guess. I am 26years old and have two little girls ages 6 and 3. They are both smart and strong but they have both inherited medical issues. My 6 year old especially. She has Celiac, dairy intolerance, some unknown allergy causing eosinophilic esophagitis (inflammation in her esophagus), and it seems she may have Periodic Paralysis like I do (causes temporary weakness/paralysis). She also has asthma related to animal dander. She had to get ear tubes in and her adenoid removed because her ears wouldn't release all the fluid it collected so she couldn't hear properly and her adenoid was swollen and causing problems. Shes been to the doctor way more than average and obviously, that's tough to deal with. My younger daughter is dairy intolerant and the doctor thinks she also has Celiac as well as a fairly benign skin condition called kopilaris pilaris (or something like that, maybe if she guts gluten it will go away*.*). With all of this plus my own conditions, (Hashimoto's Thyroiditis, Celiac, Normokalemic Periodic Paralysis) I'm wondering if I would be doing a disservice to my family and myself as well as any new baby if I were to get pregnant again. Like logically, it seems having a baby knowing all the risks now, would be a bad idea. Tough pregnancy's plus tough recovery's plus baby potentially being born chronically ill; probably shouldn't anymore, right? So logically I know I shouldn't, but I'm having a hard time coping with the idea of never having a baby again. I am a lot healthier than I used to be, but being pregnant has a way of beating up the body so thinking about that has been helpful in preventing me from taking that step. But still, I'm disappointed. I would have liked to have like four kids and as it is it looks like I'll never get the chance to have those twins I always dreamed of:) (I'm a twin so I love:) Has anyone else here had to deal with this? What have you done to cope with it?
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- eosinophilic esophagitis
- family planning
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1st of all my GI is AMAZING. Not only is he a great doc, but he also is just a great guy. We had a great time, LOL!! The findings were: 1) Hiatal hernia 2) Duodenal tissue looked normal, but he took 10 biopsies to be sure. 3) I may have Eosinophilic Esophagitis, which is an chronic allergic/immune response to a certain food (we don't know what it would be), leading to a buildup of the white blood cells eosiniophils. The evidence was from rings in my esophagus that shouldn't be there. Biopsies were taken to evaluate for that. So now I wait. Only I would add another possibility onto my crazy health situation, LOL!!! He was baffled by my positive TTG celiac blood test, if the biopsy comes back negative. But at least they can see that there is SOMETHING going on in there, and that my body is reacting to something. Now we just to see if it's gluten, or if it's something else. He did recommend a 2 week trial of a gluten free diet to see if it helped alleviate any symptoms.
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