Get email alerts Get Celiac.com E-mail Alerts  




Celiac.com Sponsor:
Celiac.com Sponsor:




Ads by Google:






   Get email alerts  Subscribe to FREE Celiac.com email alerts

Gluten Issue
0

16 posts in this topic

Hello everyone: This is my first post on this forum. I've been drawn to here by Doctor John Crisler's large following. I like his stance on Testosterone Replacement Therapy.
----------------------------------------------------------------------------------------------------------------------------
Brief Bio/Description: I am a 20 year old college student whom plays tennis in the Spring. I am approximately 5'10" and 191 pounds. I have experienced a low quality of life though, since I was twelve years old.

Symptoms: depression, anxiety, constant fatigue, poor motivation, lesser erections, weight gains that are difficult to lose, and poor gains in muscle despite weight lifting 

Essentially, I feel like I am turning into a ghost of myself.

Additions (February): 

The fatigue is a major symptom lately. Also brain fog. 

Peculiarly, after I worked out recently I had two marks on both my shoulders, similar to scratches. Judging from eye, about 5 inches long. I assumed they were stretch marks. They disappeared the day after. I know that high cortisol can cause stretch marks. Obviously, I have low cortisol, but I understand there are cases in which the cortisol rises before it falls. These were not marks from lifting.

When I used the bathroom, I noticed blood on the toilet paper this morning.

When I cough, I feel a pain in the bottom left of my head. Close to my neck.

I don't know if the last two are relevant.
----------------------------------------------------------------------------------------------------------------------------
Results:

Test One- Issued by my Family Doctor

Testosterone, Serum: 265 (348-1197)
"""""
Test Two


TSH: 2.360 (0.450-4.500) 
LH: 4.2 (1.7-8.6) 
FSH: 1.1 (1.5-12.4) 
Testosterone, Serum: 330 (348-1197) 
Prolactin: 8.5 (4.0-15.2) 
"""""
Test Three- Issued by an Endocrinologist

Free Testosterone(Direct): 9.4 (9.3-26.5) 
Testosterone, Total, Lc/Ms: 253.9 (348-1197) 
LH: 4.1 (1.7-8.6) 
FSH: 1.1 (1.5-12.4)
"""""
Test Four- Issued by an Endocrinologist-- I had been off Prozac for one week at this point. This is the only test I was off it.

Cortisol: 20.8 (2.3-19.4) 
TSH: 4.2: (0.450-4.500)

I had an MRI done, and the results came back clear.
"""""
Test Five- Test I requested-- Issued by Family Doctor-- This test was after taking Synthroid 50mcgs

Thyroid Panel With TSH
TSH: 1.930 (0.450-4.500)
Thyroxine (T4): 9.6 (4.5-12.0)
T3 Uptake: 34 (24-39)
Free Thyroxine Index: 3.3 (1.2-4.9)
Thyroid Antibodies
Thyroid Peroxidase (TPO) Ab: 8 (0-34)
Antithyroglobulin Ab: <20 (0-40)
Luteinizing Hormone (LH): 7.3 (1.7-8.6)
FSH, Serum: 1.3 (1.5-12.4)
Calcitonin, Serum: <2.0 (0.0-8.4)
Reverse T3, Serum: 21.5 (9.2-24.1)
Vitamin D, 25-Hydroxy: 32.6 (30.0-100.0)
Triiodothyronine (T3): 115 (71-180)
Estrogens, Total: 83 (40-115)
Ferritin, Serum: 70 (30-400)
Triiodothyronine, Free, Serum: 3.7 (2.0-4.4)

Additions (February): 

Obviously, my Adrenal Glands are struggling. I wonder how my anxiety and stress come into play.

Salivary Cortisol Test
Morning - 3.8 ng/mL (7.0-10)
Midday - 3.1 ng/mL (3.0-6.0)
Evening - 2.5 ng/mL (2.5-4.0)
Night - 2.2 ng/mL (<1.5)

Recently, it came to my attention that Gluten Intolerance can cause a wide array of hormonal imbalances. I didn't expect anything, however my T-Transglutaminase (Ttg) lgg is high. 

Celiac Disease Comprehensive:
T-Transglutaminase (Ttg) lgg: 8 U/mL (0-5 U/mL)
Immunoglobulin A, Qn, Serum: 102 mg/dL (91-414 mg/dL)
T-Transglutaminase (Ttg) Iga: <2 (0-3)
Deamidated Gliadin Abs, Iga: 3 (0-19)
Deamidated Gliadin Abs, Igg: 6 (0-19)
Endomysial Antibody Iga: Negative


I do not know if this is important, however, these tests were taken at 8 AM. This could cause for the imbalance in some tests, as I had not eaten. I wonder if these are impacted: Calcitonin, Serum; Ferritin, Serum; and/or Vitamin D, 25-Hydoxy.

It is also important to note, I am currently taking: 50mcgs of Synthroid in the morning, 20mgs of Adderall in the morning, and 10mgs of Prozac at night. I started taking Synthroid before the last blood work.

Revision (February): I have bumped my Synthroid to 75mcgs for no other reason that optimization. I have stopped taking Adderall and Prozac. I know that stimulants can hinder the Adrenal Glands. I felt like the Prozac wasn't worth the hassle at 10mgs. It hindered my sexual performance slightly, and if I wasn't getting much out of it I didn't want to continue. I am taking 3.75mgs of Androgel 1.62%. In addition to these prescription medications, I just began taking Licorice Root and Ashwagandha for stress and my Adrenal Glands, as well as a Rainbow Light's Multivitamin.
----------------------------------------------------------------------------------------------------------------------------
Where I am at Now: My two endocrinologists have diagnosed me with unrelated Hypothyroidism and Hypogonadism caused by poor function of my Thyroid and Pituitary. Both my doctors were sure of their decision so I felt more comfortable, but I am skeptical because it seems unlikely for one my age to suffer from both without an underlying cause. 

One week ago I started Androgel 1.62%. I have a doctors appointment tomorrow and I will try to convince my doctor to prescribe HCG.

Revision (February): Now having adrenal fatigue, I am more believing that there is an underlying cause for my endocrine issues. I have an appointment at John Hopkins March 19. I hope that some headway into an accurate diagnosis will be made then.

Lately, I am feeling hopeless of the situation. Any advice is warmly welcomed.
----------------------------------------------------------------------------------------------------------------------------
Questions:
 

Diagnoses: What are your thoughts on my diagnoses? Do you think they are legitimate? I have been told that it is indeed a function problem, but I have also been told that I need to see better doctors. 
Thank you for reading.


Nate

 

Now I am looking for to see if the T-Transglutiminase (Ttg) lgg levels are dangerous. It has came to my attention that gluten intolerance can cause a wide array of hormonal problems. Please let me know what you think.

Edited by HuberNS92
0

Share this post


Link to post
Share on other sites


Ads by Google:

hmmm... about the blood in stool thing, its highly likely you have some hemorrhoids and those decided to "act up". Not all that uncommon if "D" or "C" is present for long periods of time.

 

Sounds like you should look into having the endoscopy with biopsys done to rule out celiac (or even confirm). That would be the next step.

 

It is very possible for any one at any age to suffer from anything, its just statistically not likely. For example, when my galbladder was taken out it was dx'd with something that is normally seen in women in their 40s. I was 21 at the time.

 

Generally speaking about the food before blood tests, its better to do without than it is to do with. It should be fine, i've always fasted before any blood tests i've had just in case.

0

Share this post


Link to post
Share on other sites

Thank you for the response, Shadowicewolf

hmmm... about the blood in stool thing, its highly likely you have some hemorrhoids and those decided to "act up". Not all that uncommon if "D" or "C" is present for long periods of time.

How do you diagnose a hemorrhoid? And "D" or "C"?

Sounds like you should look into having the endoscopy with biopsys done to rule out celiac (or even confirm). That would be the next step.

So I should be suspicious of Celiac's Disease with having the high T-Transglutiminase (Ttg) lgg?

It is very possible for any one at any age to suffer from anything, its just statistically not likely. For example, when my galbladder was taken out it was dx'd with something that is normally seen in women in their 40s. I was 21 at the time.

 

Generally speaking about the food before blood tests, its better to do without than it is to do with. It should be fine, i've always fasted before any blood tests i've had just in case.

I I will keep that in mind. When I did this Celiac's Comprehensive Panel I did eat gluten recently for the blood was drawn.

0

Share this post


Link to post
Share on other sites

D= Diarrhea C= constipation

 

From my understanding and experience, if you have bowl problems and it gets a little bloody and is bright red there is a very high chance that it is a hemorrhoid. You can be checked in the area by a doctor.

 

As for the high IGG, i'd think it would be enough to look into just in case.

 

Others on here would probably know more than me about the IGG number.

0

Share this post


Link to post
Share on other sites

D= Diarrhea C= constipation

I have had some of each.

From my understanding and experience, if you have bowl problems and it gets a little bloody and is bright red there is a very high chance that it is a hemorrhoid. You can be checked in the area by a doctor.

 

As for the high IGG, i'd think it would be enough to look into just in case.

 

Others on here would probably know more than me about the IGG number.

What doctor would I get to check for a hemorrhoid and an intestinal biopsy for Celiac's?

0

Share this post


Link to post
Share on other sites




Celiac Disease Comprehensive:
T-Transglutaminase (Ttg) lgg: 8 U/mL (0-5 U/mL)
Immunoglobulin A, Qn, Serum: 102 mg/dL (91-414 mg/dL)
T-Transglutaminase (Ttg) Iga: <2 (0-3)
Deamidated Gliadin Abs, Iga: 3 (0-19)
Deamidated Gliadin Abs, Igg: 6 (0-19)
Endomysial Antibody Iga: Negative

 

Hi everyone. Is this comprehensive anything to worry about? Looking at the high T-Transglutaminase (Ttg) lgg.

 

Thanks,

Nate

 

 

0

Share this post


Link to post
Share on other sites

False positives do happen on the TTG tests but we need to have some more info before we can think about that as a possibility. Your total IgA is in range which means that it should be the IgA based tests that take significance but it is also very low in the range. I am not sure how to interpret that. Can you provide us with some more info?

Age
Symptoms
Any recent infections/illnesses?
Any other autoimmune/non autoimmune diseases?
Do any diseases run in your family?

What made you pursue testing? 
 

0

Share this post


Link to post
Share on other sites

I merged the topics. This is a busy board, and sometimes things get missed.

I am not an expert on the blood tests--they were not yet in common use here when I was diagnosed. You are positive on Ttg iGg, but not by a large margin. Taken as a set, I would not consider the results conclusive either way. I am not a doctor, so I can not give a diagnosis, just my own idea based on what I have seen here in the many years I have been a member.

Antibody tests (iGa and iGg) are based on long-term immune system activity. The time of day the blood was drawn will not matter, nor will what you did (or didn't) eat for breakfast.

0

Share this post


Link to post
Share on other sites

I just found that along with the tests, I have severely low Estrogen: <3 on a range of 3-70!

 

Please, please weight in guys. I'm getting afraid of what this could be. Could all this be caused my Gluten? Or is it likely something else?

0

Share this post


Link to post
Share on other sites

TTG tests usually indicate celiac disease but they can indicate other problems too. I'm not sure if the ttg IgA tests are the same as the ttg IgG tests, but I do know that a positive ttg IgA can also indicate Hashimoto's thyroiditis, autoimmune liver disease, and I think Crohn's as well as some other problems like infections.  That being said though, when a positive TTG test appears, especially if it is quite elevated, it is usually celiac disease. Because yours is not that high, I would say that there is a small chance it is caused by something other than celiac disease... I'm not a medical professional though.

 

Because you have fairly low levels of serum IgA in your blood, that could explain why none of your tests including IgA were positive. There is the possibility that there would have been higher results if your serum IgA was not in the bottom 3% of the normal range... Low IgA levels are found more commonly in celiacs than in the regular population BTW.

 

A endoscopic biopsy (of the beginning of the small intestine) might give you more information. If damage is seen, then they know it is celiac disease. They go in through the top for this so they can't check for hemorrhoids with this test... for that you need to (ahem) check the other end.  ;)

 

Celiac disease can attack other body parts beyond the intestines. The skin is sometimes attacked, as is the liver or pancreas. Many organs and glands can be affected by the high levels of inflammation that can result from untreated celiac. There are cases of thyroiditis being induced by celiac disease, and as you know, adrenal fatigue can be caused by autoimmune stressors too.

 

In my opinion, all you can do to check for celiac disease at this point is request an endoscopic biopsy. Request a minimum of 6-8 samples to be taken so it is less likely that patchy villi damage is missed. After that, try the gluten-free diet for 3-6 months and look for improvements. Sometimes improvements are very slow to come on this diet (it took over 6 months for my joint pain to go) so you need to give it a loong time at 100% gluten-free to be really sure if there are benefits or not for you.

 

I hope you feel better soon.

0

Share this post


Link to post
Share on other sites

Hello Huber,

 

Another possibility with similar symptoms to celiac disease is non-celiac wheat sensitivity.  Some of us think of that as NCGI or non-celiac gluten intolerance.  It won't show up on the celiac disease antibody tests because it involves a different immune system response by the innate immune system vs the adaptive immune system.  Not much is known about it yet including what kind of affects it can have on the body besides GI symptoms, if any.

 

There are no tests for it yet.  To find out if you have  a problem with wheat or all gluten, you could try doing a strict gluten-free diet for 6 months to see if your symptoms improve.  I imagine you have had your vitamin and mineral levels checked?  If so you could take another test for them after 3 to 6 months and see if they have improved.

 

Non-celiac wheat sensitivity article
http://www.celiac.com/articles/23033/1/Non-Celiac-Wheat-Sensitivity-It-Exists/Page1.html

0

Share this post


Link to post
Share on other sites

Hello Huber,

 

Another possibility with similar symptoms to celiac disease is non-celiac wheat sensitivity.  Some of us think of that as NCGI or non-celiac gluten intolerance.  It won't show up on the celiac disease antibody tests because it involves a different immune system response by the innate immune system vs the adaptive immune system.  Not much is known about it yet including what kind of affects it can have on the body besides GI symptoms, if any.

 

There are no tests for it yet.  To find out if you have  a problem with wheat or all gluten, you could try doing a strict gluten-free diet for 6 months to see if your symptoms improve.  I imagine you have had your vitamin and mineral levels checked?  If so you could take another test for them after 3 to 6 months and see if they have improved.

 

Non-celiac wheat sensitivity article

http://www.celiac.com/articles/23033/1/Non-Celiac-Wheat-Sensitivity-It-Exists/Page1.html

 

Thanks for the responses guys. I appreciate it. So you are basically saying that I could have some sort of gluten reaction, and that it could be causing major problems. 

 

The weird thing is that I don't have any digestive issues. No abdominal pain, stomachaches, constipation, etc. Is it still possible for me to have it?

 

Also, I don't have my vitamins and minerals checked. But I will no if this is working because my hormone levels!!!

0

Share this post


Link to post
Share on other sites

NCGI or celiac sometimes presents silently or neurologically. For instance, I was shocked that my migraines were largely caused by gluten... I'd had no idea!

0

Share this post


Link to post
Share on other sites

Hi Huber,

 

Yes, you can have gluten issues and no GI symptoms. Read up on silent celiac.  There may be more silent celiacs than regular GI symptom celiacs.   People walking around every day without GI symptoms but with other things happening in their bodies.  They estimate over 90% of people with celiac disease are undiagnosed.

0

Share this post


Link to post
Share on other sites

Hi Huber,

 

Yes, you can have gluten issues and no GI symptoms. Read up on silent celiac.  There may be more silent celiacs than regular GI symptom celiacs.   People walking around every day without GI symptoms but with other things happening in their bodies.  They estimate over 90% of people with celiac disease are undiagnosed.

 

I understand that this is a really hard question, but just from what you guys know, do you think there is a possibility that all this could be caused by gluten??? It just seems crazy to think so! Fortunately if it is, I have a great way to test and check for improvement... my hormones!

0

Share this post


Link to post
Share on other sites

Create an account or sign in to comment

You need to be a member in order to leave a comment

Create an account

Sign up for a new account in our community. It's easy!


Register a new account

Sign in

Already have an account? Sign in here.


Sign In Now
0

  • Forum Statistics

    • Total Topics
      103,623
    • Total Posts
      918,373
  • Topics

  • Posts

    • Newly diagnosed and totally overwhelmed
      so i was just recently diagnosed with Celiac disease and I am having trouble wrapping my head around it.... While i know that maintaining a gluten free diet is going to help me feel better - i can't get over the fact that i cannot eat my favorite foods anymore.. no more pizza, no more pasta, no more wheat thins.......... yes i realize there are gluten free versions of all of these but it's obviously just not the same.  I can't just go out and grab a couple drinks at the bar with my friends anymore..... i really do not know how to handle this and it's already wearing me down.  I feel like after living for 28 years my entire life has flipped upside down and everything is going to change... i'm sorry for sounding like such a lost puppy but i just wanted to vent a little bit and see how you all deal with this... i told my friends about it and they act like it is so not a big deal at all but to me it feels like my world has come crashing down 
    • puffiness in face
      Would hot yoga help the puffiness in face due to other food sensitivities? or Asuanas? How to determine if you have a histamine intolerance or other food sensitivities? 
    • A good diet for avoiding type 2 diabetes
      I hope you do well on your new diet cristiana, whatever it turns out to be.  Another site with lots of paleo diet info is Marks Daily Apple.  He also lists cooking oils that are good for you vs bad for you to eat.  Try searching his site for topics of interest.  I am not too interested in the paleo diet backstory as such.  But it seems like a good diet for many people to try at least. The diabetes forum has good info also, from people with diabetes vs doctors.  They used to have a chat for people to ask questions, but I don't know i that is still active.  From memory, some of the people there limited themselves to 1 cracker a day's worth of carbs.  And they were off their medication completely.   Mostly against doctors advice about diet, but some doctors give bad advice about diabetes to people.  Like telling people they have to eat carbs to be healthy, which is not true. http://www.diabetesforum.com/forum.php
    • Symptoms In Toddlers?
      Good evening, I tested positive about 15 years ago. I have a 3 year old son and a 1 year old daughter. I just had them both tested for Celiac's. Ped ran a celiac panel. My son the nurse said was all in normal range however my daughters IGA total was 23, range (24-121) so she test positive. The doctor wants to run more blood work to make sure it's not a false positive. My gut says she has it. She does not like any bread or cookies so she really only gets gluten from pasta and goldfish so to even test positive on an almost gluten-free diet make me concerned. Is there anything I should ask the doctor to test for or better tests for kids? I just don't want to miss anything.  Before when I would bring it up at visits the doctors always said that since they did not have any failure to thrive ( always top of growth charts) that they weren't showing any symptoms. I never had any issues with losing weight.  My only complains or constipation joint pain and gas which she has both. Thanks for any advice.    
    • food allergies
      being new to this, I have started avoiding gluten and dairy. I seem to be sensitive to other foods like corn, tomatoes, bananas, and possibly grains and sugars. I still get puffy in the face whenever I eat certain things. other than blood testing, does any meds help with this? Also, is gas X gel tablets ultra strength gluten free? 
  • Upcoming Events

  • Blog Entries

  • Recent Status Updates

    • celiac sharon  »  cyclinglady

      Hello cycling lady, have you noticed my picture is showing up as you?  Have no idea why but it's rather disconcerting to see my picture and your words 😉  Do you know how to fix it?  You seem to have far more experience with this board than I do
      · 1 reply
    • Larry Gessner  »  cyclinglady

      Hi There, I don't know if there is a place for videos in the forum. I just watched "The Truth About Gluten" I think it is a good video. I would like to share it somewhere but don't know where it should go. Any help would be greatly appreciated.
      Here is the link if you have never watched it.
      https://youtu.be/IU6jVEwpjnE Thank You,
      Larry
      · 2 replies
    • ChiaChick  »  Peaceflower

      Hi Peaceflower, Just wanted to say thank you for the chat.
      · 0 replies
  • Who's Online (See full list)

  • Member Statistics

    • Total Members
      60,715
    • Most Online
      1,763

    Newest Member
    Acomys
    Joined