Posted 18 April 2013 - 09:10 AM
With a tTG that high I'd be pretty darn confident -- and it may be tough to keep eating gluten for six months when you know you are likely causing damage to your small intestine.
I'd suggest removing all gluten with your wife -- often those without obvious symptoms become more sensitive after removing gluten -- in the coming months you may find you start reacting to accidental gluten ingestion.
There is no reason why you can't have a full celiac panel and endoscopic biopsy after six months gluten-free -- hopefully it will show that six months has decreased your antibody level and that your small intestine is in healthy shape.
Oh there are labs -- even in small towns that can run a full celiac antibody panel for about $200. Also, if possible get blood taken for Vitamins B12, D, Iron -- if you can add in: B1, B2, B6, K, Ferritin Copper, Zinc and a CMP -- getting these done before you remove gluten can help -- as celiac disease can prevent absorption of these key nutrients.
Good Luck -- ask questions and read as much as you can -- it really does speed a tough transition.
PS...the country is a great place to find healthful whole gluten-free foods
Undiagnosed Celiac Disease ~ 43 years
3/26/09 gluten-free - dignosed celiac - blood 3/3/09, biopsy 3/26/09, double DQ2 / single DQ8 positive
10/27/09 diagnosed fibromyalgia - supplemented with amino acids - improvement followed by substantial deterioration
maybe one good hour per day for ~17 months
8/10/11 - Elimination Diet for Autoimmune Disease - incredible improvement along with clear reactions to most high lectin foods
only remaining symptom - severe heat intolerance / reaction to heat, humidity and exercise
Tomato, Pepper, Potato, Peanut, Soy, Bean, Pea, Citrus, Pineapple, Avocado, Shellfish, Dairy, Grain, Nut and Seed FREE
3/1/12 - Horrible flare -- same ol' symptoms but worse ~ 7/1/12 - Endo: Active Celiac 3+ years - as gluten-free as humanly possible.
11/15/12 - Improving once again - Almonds back - Eggs gone
12/1/12 - Histamine containing and inducing foods FREE -- probable cause of my heat/exercise "allergy"...
...this was one of my earliest symptoms as a child -- the enzyme (DAO) needed to regulate histamine is created in the small intestine.
If you have read this far - hang in there - obtaining health with any AI is a marathon, not a sprint!
Celiac.com - Celiac Disease Board Moderator