With a tTG that high I'd be pretty darn confident -- and it may be tough to keep eating gluten for six months when you know you are likely causing damage to your small intestine.
I'd suggest removing all gluten with your wife -- often those without obvious symptoms become more sensitive after removing gluten -- in the coming months you may find you start reacting to accidental gluten ingestion.
There is no reason why you can't have a full celiac panel and endoscopic biopsy after six months gluten-free -- hopefully it will show that six months has decreased your antibody level and that your small intestine is in healthy shape.
Oh there are labs -- even in small towns that can run a full celiac antibody panel for about $200. Also, if possible get blood taken for Vitamins B12, D, Iron -- if you can add in: B1, B2, B6, K, Ferritin Copper, Zinc and a CMP -- getting these done before you remove gluten can help -- as celiac disease can prevent absorption of these key nutrients.
Good Luck -- ask questions and read as much as you can -- it really does speed a tough transition.
PS...the country is a great place to find healthful whole gluten-free foods
Undiagnosed Celiac Disease ~ 43 years
3/26/09 gluten-free - dignosed celiac - blood 3/3/09, biopsy 3/26/09, double DQ2 / single DQ8 positive
10/25/13 - MCAD
Health history since celiac diagnosis became too long -- moved to the "about me" section of my profile
My children and I all have multiple copies of the genes for Celiac Disease, along with large variety of symptoms/resolution gluten-free
Current tally from me, three kids and two grands: 4 diagnosed with Celiac Disease, 2 NCGS
Get PROPERLY tested BEFORE REMOVING GLUTEN.
ALWAYS independently research health related information found on internet forums/blogs.
"LTES" a Gem