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      Frequently Asked Questions About Celiac Disease   09/30/2015

      This Celiac.com FAQ on celiac disease will guide you to all of the basic information you will need to know about the disease, its diagnosis, testing methods, a gluten-free diet, etc.   Subscribe to FREE Celiac.com email alerts What are the major symptoms of celiac disease? Celiac Disease Symptoms What testing is available for celiac disease? - list blood tests, endo with biopsy, genetic test and enterolab (not diagnostic) Celiac Disease Screening Interpretation of Celiac Disease Blood Test Results Can I be tested even though I am eating gluten free? How long must gluten be taken for the serological tests to be meaningful? The Gluten-Free Diet 101 - A Beginner's Guide to Going Gluten-Free Is celiac inherited? Should my children be tested? Ten Facts About Celiac Disease Genetic Testing Is there a link between celiac and other autoimmune diseases? Celiac Disease Research: Associated Diseases and Disorders Is there a list of gluten foods to avoid? Unsafe Gluten-Free Food List (Unsafe Ingredients) Is there a list of gluten free foods? Safe Gluten-Free Food List (Safe Ingredients) Gluten-Free Alcoholic Beverages Distilled Spirits (Grain Alcohols) and Vinegar: Are they Gluten-Free? Where does gluten hide? Additional Things to Beware of to Maintain a 100% Gluten-Free Diet Free recipes: Gluten-Free Recipes Where can I buy gluten-free stuff? Support this site by shopping at The Celiac.com Store.

What Are Brush Border Enzymes And How Do They Related To...
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6 posts in this topic

Hi,

 

I am still learning about enzymes. I have leaky gut, and after trying my first bottle of a general enzyme product, I noticed some benefits, so I became more interested to learn about enzymes. Today I came across a new term called "Brush Border Enzymes". The short explanation I saw was very relevant to being Celiac and/or have leaky gut. Apparently, some individuals have damaged brushed border (part of small intestine  where a few enzymes are produced). These enzymes are responsible for breaking down many foods that if not broken down will cause allergies.... 

 

My question is:

1. What is the list of these enzymes?

Why do I ask? because there is no reason for me to buy a enzyme product that has plenty of enzymes that I don't need.. I want to know what are exactly these "Brush Border Enzymes" so I look for products that have those in them only.

 

2. Can anyone recommend any enzyme supplements that have these enzymes in them? I mean all of them not just one or two. I am looking for 1 complete product. thanks

 

 

As always, all input is appreciated. 

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Hmmm...

 

I found this: http://www.vivo.colostate.edu/hbooks/pathphys/digestion/smallgut/bbenzymes.html

 

It lists Glucoamylase (Maltase); Sucrase-Isomaltase; Lactase; and Peptidases.

 

I can't help about products, as I have been curious but haven't tried any. If you don't mind my asking, what enzymes did you use and what benefits did you experience?

 

Thanks for posting this, I'm wondering if I've got 'brushy borders' myself lolz...

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Hmmm...

 

I found this: http://www.vivo.colostate.edu/hbooks/pathphys/digestion/smallgut/bbenzymes.html

 

It lists Glucoamylase (Maltase); Sucrase-Isomaltase; Lactase; and Peptidases.

 

I can't help about products, as I have been curious but haven't tried any. If you don't mind my asking, what enzymes did you use and what benefits did you experience?

 

Thanks for posting this, I'm wondering if I've got 'brushy borders' myself lolz...

Well the enzyme product I used is called Digest Spectrum by Enzymatica. but I am frustrated because I can see that it is not perfect for my body but helps alot! Another words there are some enzymes in it that my body can use very much and some not so much...

I wish there was a enzyme test that could measure all the digestive enzymes and stomach acids and bile in a person's body and tell me exactly which enzymes I need and exactly in what quantity  so I didn't have to do this trail and error with all these enzyme products!! But I guess this idea is way ahead of it's time! :)

 

But since I put up this post, I have been doing some research and trial and error by googling every enzyme that is in that formula of "Digest Spectrum" and educating myself on them.....Although I am not done, here is all my finding that I can share today:

 

1. Alpha Galactosidase(Helpful when taken with food) - . Digest Spectrum has 300 GaIU of this enzyme in it(Per 1 cap). This enzyme helps digest cruciferous vegetables. Interestingly enough, it is the main enzyme in the product "Beano" . Beano has 150 GalU per tablet, so I tried 2 Beano tablets because I wanted to use equal amounts. So I went ahead and bought some Beano and tried it with my food and it really helped with bloating. It does not cure bloating completely but helps! Especially because I have been eating Sauerkraut lately to boost my good bacteria, and sauerkraut is made from cabbage which is a cruciferous vegetable. 

 

2. DPP-IV (helpful when taken with food)- This is the enzyme that along with protease is suppose to help break down Gluten. Digest spectrum has 1,400 DPPU. So again I did some research to see if I can find this enzyme on it's own so I can try it and see what happens when I use it as a single enzyme,... I could not find it sold by itself like I did with Beano because I guess this enzyme has to be combined with protease to work, but it was obvious after a little reseach that this enzyme is the main componets of most Gluten Enzyme formulas out there such as Glutenease, Gluten Flam, Gluten Digest and........ I happened to have a 1/2 open bottle of Gluten Digest(by NOW) from a while back, so I got it out and started using it on it's own for a few days.... It helped alot with inflammation and gas... I don't eat anything with wheat anyways, but I eat Quinoa or Rice with 2 of my meals and the product helped with digesting those alot.

 

 

 

3. Cellulase(NOT helpful when taken with food) - This is the enzyme that helps digest fiber. It is also the main component of most products out there that is suppose to help with Candida cleanse. However, I highly suspect this is the enzyme that I don't need to take with food. Another words, when I said earlier that Digest Spectrum is not perfect for my body it is because it has this enzyme in it. This enzyme is usually combined with a few other enzymes to help cleanse candida. If you do some research and read some lables, you can see that Cellulase is the main component in most products that are geared towards Candida cleanse. Products such as Candex,  Candidase, CDX Yeast and many more enzymes geared towards candida cleanse all pretty much have this enzyme as their main components. But here is the reason why I wish it was not included in Digest Spectrum. You see, Cellulase works well on an empty stomach. This is why products such as Candex are taken 2 hours before eating in the morning or night... because it's suppose to go in the intestine on its own and break down the candida. But the formula "Digest Spectrum" is designed to be taken with a meal!............hmm, what to do?? Well, I also had some Candex that I used to take for candida. I decided to try to take a capsule with a meal instead of my usual way of taking Candex which is to take it when I wake up in the morning or before I go to sleep at night... and when I took it with a meal, it actually gave me more bloating and inflamation!..... this is why I know Digest Spectrum is not perfect for my body, because it has Cellulase in it and I only should take that enzyme on an empty stomach... but I have no choice with Digest Spectrum because it's already in there

 

My Next project:

Xylanase - One of the things that Digest Spectrum does for me that I was puzzled about is that it enhances my mood! I realized after a couple of days of taking Digest Spectrum I was laughing more and not so easily irritated like I usually am. I could not understand how this was possible. So I stopped Digest Spectrum for a few days and the feelings of irritability came back!  Started it again and it went away! :) I knew there was something in that Digest Spectrum that was making me happy and I have been wanting to know what it is........ The biggest suspect is this Xylanase.... Again if you do some research and read some lables, you will see that Xylanase is the main component of most products that are geared towards digesting Phenols. The 2 main products made for that are: No Phenol (Houston) and Carbgest(Enzymatica)... so my next project is to buy one of these (either Np Phenol or Carbgest) and try and see if it enhances my mood like Digest Spectrum does...... Digest Spectrum has 20,000 XU of Xylanase, where as No Phenol has 32000XU and Carbgest has 38000XU

 

 

 

So basically, at this point in time, I have to do all this research so I can find out which enzymes my body really needs and at what quantity and should it be taken with a meal or on an empty stomach....... Hopefully, someday they come up with a test that can tell each individual what their body needs because what i can digest someone else can not!

 

Good luck to all! 

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BTW, just wanted to add, I use this web site to look up Ingredients on enzymes:

 

http://pureformulas.com

 

Not saying to buy from them, I just use their site to pull up labels on all of the enzyme products when I want to look it up. Their web-site is the best I found so far for that purpose.

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Wow, thanks, that's a lot of good info!! I may try the Digest Spectrum to see if it helps.

 

But a word of warning -- last time I checked, Beano contains wheat :(

 

PS. Interestingly, the Beano site in Spanish says the levels of gluten in the product are less than the lowest detectable levels, but the website in English makes no mention of it.

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I have since switched to TriEnza with DPP IV Activity  made by Houston,

I found it has all that Digest Spectrum had except the Cellulase which I did not want. I feel like this works best for me .... 

 

 

I also do take 1 Beano capsule whenever I am eating cruciferous vegetables 

and I have no allergic reaction(thank God) to Beano, and it helps limit Gas/Bloating ... And 1 350mg 

Betaine HCL and i am now 42 and my belly is less bloated and more flat than when I was 22! ... I also feel like my food is digesting better and I seem to have more energy..... 

 

anyways, I think I am done with this subject of "Digestive Enzymes" for now as I have found what works for me,

my next project is get rid of my candida!

 Good Luck to you all! 

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