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    • Frequently Asked Questions About Celiac Disease   09/30/2015

      This FAQ on celiac disease will guide you to all of the basic information you will need to know about the disease, its diagnosis, testing methods, a gluten-free diet, etc.   Subscribe to FREE email alerts What are the major symptoms of celiac disease? Celiac Disease Symptoms What testing is available for celiac disease? - list blood tests, endo with biopsy, genetic test and enterolab (not diagnostic) Celiac Disease Screening Interpretation of Celiac Disease Blood Test Results Can I be tested even though I am eating gluten free? How long must gluten be taken for the serological tests to be meaningful? The Gluten-Free Diet 101 - A Beginner's Guide to Going Gluten-Free Is celiac inherited? Should my children be tested? Ten Facts About Celiac Disease Genetic Testing Is there a link between celiac and other autoimmune diseases? Celiac Disease Research: Associated Diseases and Disorders Is there a list of gluten foods to avoid? Unsafe Gluten-Free Food List (Unsafe Ingredients) Is there a list of gluten free foods? Safe Gluten-Free Food List (Safe Ingredients) Gluten-Free Alcoholic Beverages Distilled Spirits (Grain Alcohols) and Vinegar: Are they Gluten-Free? Where does gluten hide? Additional Things to Beware of to Maintain a 100% Gluten-Free Diet Free recipes: Gluten-Free Recipes Where can I buy gluten-free stuff? Support this site by shopping at The Store. For Additional Information: Subscribe to: Journal of Gluten Sensitivity

Gfd Compliance With Dgp Vs. Ttg Testing

1 post in this topic

every so often I like to see if there are any new studies added related to DGP, and here's an interesting abstract I found:


it says that 55 patients with known celiac disease, though it doesn't say biopsy proven, were tested for compliance to GFD.  It would have been great if it was said whether these patients previously tested positive for both DGP and TTG before going on a GFD.  


Results after a GFD:

24/55 of those tested positive for DGP

Out of those results:

12/24 had an elevated ttg iga serum above the normal reference range of <10

9/24 had a ttg iga result between 3-9

3/24 had a ttg iga result of <1


All patients who tested negative for DGP were also ttg iga negative: 31/55 


The paragraph of self reporting reads as follows:

"If serum IgA anti tTG is used as a measure of compliance to GFD, then the sensitivity of anti-DGP in predicting dietary compliance was 100%, with a specificity of 72% and a negative predictive value of 100%. When compliance was determined based on patients' self-reporting during the consultation, 11 (20%) patients were documented as not fully compliant to GFD. 8 (72.7%) of these were anti-DGP positive and had elevated serum IgA anti tTG, and 3 were anti-DGP positive with IgA anti- tTG level in the normal range (with their IgA anti tTG level ranged between 3 to 9 U/ml). Four (7.3%) patients reported compliance to GFD but had positive anti-DGP tests and elevated IgA anti tTG levels."


Looks like DGP still out performs ttg iga in dietary compliance!  


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