Get email alerts Get Celiac.com E-mail Alerts  




Celiac.com Sponsor:
Celiac.com Sponsor:




Ads by Google:






   Get email alerts  Subscribe to FREE Celiac.com email alerts

Can Soy Intolerance Cause Villous Atrophy?
0

7 posts in this topic

Intolerances suck. But I always assumed that even though they sometimes cause similar reactions as gluten, that they do not cause the same kind of damage to the vili as does gluten for people with Celiac disease.

 

However, I'm doing a little research, and turns out there's some evidence that intolerances to dairy/soy/corn/etc might cause villous atrophy. Anyone else know about this? (There have probably been similar discussions before, but new info/research is always good

 

Here's some stuff I found regarding soy intolerance:

http://www.ncbi.nlm.nih.gov/pubmed/987760

not the full article, but here's a study of infants with dairy intolerance who also showed vilous atrophy when they ate soy. Hmmm

 

This info was based on the study, about soy intolerance:

http://emedicine.medscape.com/article/932026-overview

"Small-bowel atrophy has been documented in different studies. The degree of villous atrophy may be similar to that found in celiac disease"

 

I didn't have a biopsy before I went gluten-free, and my bloodtests (done about a year before and just before going gluten-free) came back negative, but Celiac runs in both sides of my family. I'm self-diagnosed, but have always considered myself Celiac. However, I also have dairy and soy intolerances. I had a biopsy last fall to check of any problems, and they did see some mild gastritis but, not surprisingly, no villi damage. I hadn't eaten gluten for 4 years, and cut out dairy and soy the year before.

 

The big question from all of this is, if other foods can cause the same damage as gluten, then a: is this why a lot of people don't get better on the gluten-free diet alone, and b: could negative blood work but a positive biopsy when testing for celiac actually show damage from something other than gluten, or as well as gluten?
So, theoretically, if someone was still having problems a couple years after going gluten free, doing another biopsy might not be a bad idea to check for villous atrophy that could be caused by other proteins. Has anyone ever done this? Of course, seeing more damage still wouldn't tell you what's causing it, but could be proof that another intolerance is wreaking havoc on your gut.

 

Anyway, any other research, thoughts, etc would be helpful. All very interesting stuff.

 

Cheers

Peg

0

Share this post


Link to post
Share on other sites


Ads by Google:

I am a type 1 diabetic and have a first cousin who is also type 1diabetic and has celiac disease.  My HLA typing is DQ2, which also puts me at increased risk for celiac disease.  Over the last 12 years, I had unexplained iron deficiency; and over the last several years, I lost quite a bit of weight.  Several years ago, I switched from whole grains to just brown rice suspecting I might have celiac disease or gluten intolerance.  One year ago, I had antibody tests and a biopsy which turned out to be negative for celiac disease.  The biopsy did show a few lymphocytes, but nothing diagnostic.  That being said, if I ate any food containing gluten, I would develop GI distress--so I continued with the gluten free diet, but the weight loss continued.  Several months ago, I found a publication indicating that apple juice of all things could worsen inflammatory bowel disease.  Interestingly, for the last 33 years, I've used apple juice to treat low blood sugar.  After finding out about apple juice, I switched to blueberry juice.  And having made this change, my weight now appears to be slowly moving into an uptrend.  So the bottom line is that other foods can cause inflammation of the gastrointestinal tract--especially if you have a genetic predisposition for a particular gastrointestinal disease, be it celiac disease or inflammatory bowel disease.  As for whether or not you should have another biopsy, I kind of wonder if you take a closer look at what you are presently eating whether you might find some other food or foods that may be continuing to cause gastrointestinal problems for you.

0

Share this post


Link to post
Share on other sites

Oh, I'm definitely not running off to have another biopsy. I know that gluten/soy/dairy is bad for me, and having to eat them again would be, well, not good.

I was just curious whether anyone else had seen further research/evidence, etc.

 

Apple juice is extremely high in fructose, so much that it's really not that good for you. Glad the blueberry is helping.

0

Share this post


Link to post
Share on other sites

Oh, I'm definitely not running off to have another biopsy. I know that gluten/soy/dairy is bad for me, and having to eat them again would be, well, not good.

I was just curious whether anyone else had seen further research/evidence, etc.

 

Apple juice is extremely high in fructose, so much that it's really not that good for you. Glad the blueberry is helping.

The publications on soy appear to stem from (ie: caused by) soy protein isolate--not soy beans per se.  That being said, if you have an allergy to soy protein, you should definitely avoid soy beans.  As for the problems with dairy, they extend way beyond dairy.  In the United States, cows and chickens are fed grains rather than grass, resulting in the production of fats which are rich in omega-6 fatty acids, which in excess can cause significant inflammation.  Whereas 100% grass fed chickens lay eggs with a balanced omega-6 to omega-3 fatty acid ratio of about 1:1, grain fed chickens lay eggs with an omega-6 to omega-3 fatty acid ratio of about 20-30:1.  Similar results are found with grain-fed cows (beef), cow milk, chickens, and grain-fed ("farm-raised") fish such as tilapia.  An excellent book with literature references for these findings was written by a physician with brain cancer who used his knowledge of nutrition to keep his cancer at bay for many years:  "Anti-Cancer:  A New Way of LIfe" by David Servan-Schreiber, MD, PhD.  Just Google the title and you'll find the book available through Amazon.com.  I highly recommend it.  You will more than likely get a lot of information about the foods and food derivatives you are consuming which may be adding to any problems that you may still be having. 

0

Share this post


Link to post
Share on other sites

NutritionGuy, I heard this doctor on a radio program quite a while back. Can't remember now if it was People's Pharmacy or some other NPR show. It was so interesting. It sure seemed that his nutritional choices kept him alive much longer than if he had just kept eating the way he used to.

 

Also, I've got to ask you based on your name and the knowledge you seem to have - are you a nutritionist or a dietition, or maybe even a doctor? Whichever or none of the above, welcome to the forum and thanks for your input!

0

Share this post


Link to post
Share on other sites




Bartful:  I have a very strong strong scientific background.  That being said, most of what I am posting is based on personal experience as well as my knowledge of the scientific literature.  As for David Servan-Schreiber, I only came across his book by accident, and I was very profoundly influenced by what he wrote.

0

Share this post


Link to post
Share on other sites

I am off soy in any and all forms.

I've heard about some people reacting to eggs/meat from grain-fed animals, but never noticed any difference myself.

 

In any case, still no more info on whether or soy or other proteins (casein, corn...) could cause villous atrophy in the same way that gluten does?

0

Share this post


Link to post
Share on other sites

Create an account or sign in to comment

You need to be a member in order to leave a comment

Create an account

Sign up for a new account in our community. It's easy!


Register a new account

Sign in

Already have an account? Sign in here.


Sign In Now
0

  • Forum Statistics

    • Total Topics
      103,872
    • Total Posts
      919,408
  • Topics

  • Posts

    • Help
      Ok so I had my colonoscopy & endoscopy last Thursday. Don't get results until July 13th as GI is on vacation. I've had bad pain in my lower left abdomen that wraps around to my lower back as well for the past 4 days..even hurts to touch lightly. Went back to the ER & they did an ultrasound & CT scan. The Doctor said that I have "prominent" lymph nodes in the area that is painful as well as thickening & inflammation of my Sigmond colon? Um ok what is that all about? Kind of freaking out over the whole swollen lymph nodes thing. Has anyone ever dealt with this before? 😒
    • Enormous Stool
      My 2 year old daughter has sufferd with extremely large stools for over a year. She will have a bm once or twice a week there has been blood sometimes i took her to the docs and they gave her some stool softner which didnt help they tried uping the dose which still didnt help and they told me it would eventually work which didnt she was then put on movicol which she was only supposed to get half a sachet still no diffrence i uped it to the the full sachet which helps a little she doesnt always have large stools but most of the time she does. She has got to a stage where she clenches and wont let it out because of how sore it is i try to put her on the toilet for it to come a little easier for her but she screams and will try hide herself in a corner and wont let you anywere near her it is heart breaking to watch her. If anyone has any in advice i would really like to hear.   Thanks.
    • Starting Over with GI Dr.
      Everything I have learned I have learned through this forum or simply from my last EGD results and labs and then looking them up on the internet.  The drs have given no information except for do a gluten free diet.  My understanding is that a repeat EGD is needed to confirm healing.  When I was tested about this time last year I was a Marsh3b.  Which in my research is pretty serious.  I am still having ill effects from god only knows what these days.  I went strictly gluten free June 2015.  I have had glutenings (not by choice) and the last one I had was because of an antibiotic that I took that has sent me through the roof with anxiety issues.  I try to be as careful as possible but it is like it doesn't seem to matter how careful I am I am either aching and hurting in my joints, tired all the time or OK one minute and the next feel like crap and that my world is about to end.  It is very frustrating to say the least when you go to the dr and you are expecting support or some sort of answer and don't get one.  I have eliminated milk from my diet as of about a month and a half ago.  That seemed to help, some.  But I still have days where I hurt and ache in my elbows and in my hands.  I have moments when I am about to freeze to death and sit with a heater and where I live the temps outside are 90+ degrees plus humidity and the AC is not even on.  Most of this has just started happening I would say in the past 4 months or so.  At night when I go to bed I wear sweat pants and a sweat shirt and sleep under 4 blankets and a sheet.  They say my thyroid is fine.  I feel like I have some issues with my nervous system but to be honest with you I haven't seen drs enough to mention this to them because all they are worried about is if I have diarrhea.  Cycling Lady I will be keeping any all records that I have and continue to gather the ones for anything I have done in the future.  .  I have been through health issues with my husband and would keep all of his records and labs so we would have proof.  Just seems like doctors don't care anymore.  The last GP I went to actually listened to me and I will see her again next month after the EGD.  I did give ALL of my records, EGD, labs, medical records, etc. to the new GI prior to our first visit back in January.  She said she reviewed them.  And told me we would re-draw the labs and schedule EGD to check healing when I went to her this month.  We have scheduled the EGD but no mention of labs.  JMG I am having the procedure re-done so that I can see if I am healing.  Mostly because of all the ailments I still have or seem to be developing every day.  I used to be a person who could remember things and get things accomplished but lately that has not been happening and scares me more and more every day. I understand that no procedure is risk free.  I have had 2 C-sections, wisdom teeth removed and tubal ligation.  Each one had its own issues after they were done.  I am a person who has to see it to believe it I guess.  If I don't see it, it is hard for me to understand it.  It is hard to figure this out when I am the one who usually takes care of everyone else but then when I need to be taken care of, nobody knows what to do.  I think that is it in a nut shell.  All that ya'll have told me is a big help.  Around here I have no support groups or even a good friend I can talk to about stuff that would even come close to understanding.  My husband will listen, but he doesn't understand.   
    • Loved ones with Celiac in nursing home
      It will be in Gluten-Free Living later this year, October I think
    • Prague Looks for Consensus on Adolescent and Teen Celiac Disease Management
      The Prague consensus report looks to shine some light on the best options for providing optimal transition into teen and adult healthcare for patients with celiac disease. View the full article
  • Upcoming Events

  • Blog Entries

  • Recent Status Updates

    • Jmg  »  admin

      Hello Admin!
      I don't know whether this is of interest to post on your articles feed:
      http://pratt.duke.edu/about/news/window-guts-brain
      Kind Regards,
      Matt
      · 2 replies
    • celiac sharon  »  cyclinglady

      Hello cycling lady, have you noticed my picture is showing up as you?  Have no idea why but it's rather disconcerting to see my picture and your words 😉  Do you know how to fix it?  You seem to have far more experience with this board than I do
      · 1 reply
    • Larry Gessner  »  cyclinglady

      Hi There, I don't know if there is a place for videos in the forum. I just watched "The Truth About Gluten" I think it is a good video. I would like to share it somewhere but don't know where it should go. Any help would be greatly appreciated.
      Here is the link if you have never watched it.
      https://youtu.be/IU6jVEwpjnE Thank You,
      Larry
      · 2 replies
  • Who's Online (See full list)

  • Member Statistics

    • Total Members
      60,906
    • Most Online
      1,763

    Newest Member
    staceyO1
    Joined