Get email alerts Get Celiac.com E-mail Alerts  




Celiac.com Sponsor:
Celiac.com Sponsor:




Ads by Google:






   Get email alerts  Subscribe to FREE Celiac.com email alerts

Recurrent Miscarriage And Celiac?
0

5 posts in this topic

After multiple miscarriages, despite the birth of a healthy son in2010, I started seeing a naturopath. She ordered a ton of blood work, including the panel for celiacs. I met with her yesterday and she believes I have it and wants me to do the genetic testing, which I have no problem with. However, I'm totally baffled that she would leap to celiacs given my results and my research here and elsewhere on the internet. 

 

I would really appreciate some feedback on these results: 

 

Deamidated Gliadin Abs, IGA <1 (negative 0-19)

Deamidated Glaiadin Abs, IgG 5 (negative0-19)

t-Transglutaminase  (tTG) IgA <2 (negative 0-3)

t-Transglutaminase (tTG) IgG <2 (negative 0 - 5)

Endomysial Antiody IgA  negative

Immunoglobulin A, Qn, Serum <15  Low (Negative 91- 414) 

 

From what I've read in my crash course in celiacs in the past 24 hours, the last one indicates that all the IGA tests are invalid. It seems most people recommend the tTG tests to rule out Celiacs, yes? So being that those are also negative, why would she assume celiacs? My understanding is that low IgA serum can be indicative of many immune deficiencies so why the leap to Celiac's? 

 

Also, I have been gluten-free for approximately 6 weeks, 5 when these labs were taken, merely because there is an association between gluten and recurrent miscarriage. From what I understand gluten would have to be out of my system for much longer than that to skew the tests in any way. Correct? 

 

There seems to be a lot of experience (unfortunately) here on these forums so I'm optimistic someone can calm my frantic mind before I can connect with my Naturopath again ;)  

 

Thanks in advance!! 

0

Share this post


Link to post
Share on other sites


Ads by Google:

Looks like she did every possible blood test and they are all negative. Even tho your IGA is low, they did the IGG version, too. Cleiac can cause miscarriages. Perhaps you should consult an MD OB/GYN?

0

Share this post


Link to post
Share on other sites

You might want to consider an endoscopic biopsy if you think celiac disease is an answer (based on symptoms or familial history). Some people will have negative blood work and a positive biopsy - it's not common but it's not rare either.

 

Some people's antibody levels can fall to normal within weeks, for some it takes much longer. The problem is that there is no way of knowing which group you fall into except to resume eating gluten for about 6 weeks and then retest (the IgG tests that is).

 

Do you have other symptoms of celiac disease besides MC's (so sorry to hear about that) and low IgA that made your NP suspect celiac disease?  Are you feeling better gluten-free?

0

Share this post


Link to post
Share on other sites

Blood results as well as endoscope testing will Not be reliable since you are already gluten free.  More tham likely you may have false negatives do to being on a gluten free diet for the five weeks prior to testing.

 

The blood tests look for the antibodies your body produces in response to the gluten you eat so when you remove the gluten the body has nothing to form antibodies against so there none for the blood tests to read.  Yes you could still have villi damage that can only be seen by doing a endoscope and taking samples of the intestines. But depending on how badly the damage internally was there also may come out negative do to the damage healing which starts within 24 hours of total removal of gluten from the diet.

 

 

So your best option is the genetic test unless you're willing to go back to eating gluten for 6-12 weeks and then having the blood work and endoscope done. But still if you do have a gene linked to Celiac you may not actually have active Celiac so also do go to a reproductive specialist if you aren't already.

1

Share this post


Link to post
Share on other sites

Your celiac test results could well be invalid because you were off gluten. Hard to say.

 

If I were my 30-something year old self again (after having had multiple miscarriages and never carrying to term), I'd go to a reproductive endocrinologist. I know a whole lot more now than I did back then and one is:  Fertility doctors may not get to the root of the problem.

and the other is: Naturopaths have their value, but for this particular health issue, you need a specialist,  IMHO.

 

Could it be a gluten-related issue--and not necessarily celiac? absolutely. Plenty of medical lit that discusses this relationship.

1

Share this post


Link to post
Share on other sites

Create an account or sign in to comment

You need to be a member in order to leave a comment

Create an account

Sign up for a new account in our community. It's easy!


Register a new account

Sign in

Already have an account? Sign in here.


Sign In Now
0

  • Forum Statistics

    • Total Topics
      104,691
    • Total Posts
      921,764
  • Topics

  • Posts

    • Are you vegan or vegetarian?   I am concerned about your lack of protein and fats in your diet.  These diets can work when you are also gluten free, but as a celiac you can be malnourished.  It is hard to heal when you are slowly starving yourself.   No offense, but some newly diagnosed celiacs end up with food disorders.  Perhaps working with a dietician can help.   What actually are your blood glucose levels?  Did you know that just as Hashimoto's is common with celiacs, so is type 1 diabetes?   Ask your doctor for antibodies testing for Type 1 diabetes (TD1), if your blood glucose levels are not in the normal  range.  You can develop TD1 (LADA) at anytime.   For adults there is a "honeymoon" period which can last for up to five years.  Be on the watch for other AI issues (besides TD1) too.   It is so important to monitor your health after a celiac disease diagnosis!  
    • He was not IGA deficient.  I'm still hoping we can convince the base GI to approve his referral.   Thanks for that thread about TTG Igg.  That's exactly what I was wondering. 
    • Star Anise Foods  rice paper and spring rolls are gluten free they have brown and white rice versions. I have not had issues with these in the past when I used to use them. Should be able to find them on amazon.
    • Hi strawberrymoon, If you are having a blood sugar problem, that can cause nerve damage and tingling.  Nerve damage is often associated with diabetes.  You can ask your doctor to check your A1C level to get an idea how it has been doing. It would probably help your glucose levels to stick with a paleo style diet, avoiding most carbs.  Carbs and meats have a different affect on blood glucose.  Carbs tend to spike blood glucose while meats even it out. There are a lot of negative changes that can happen with high blood glucose.  It is wise to try and get it under control ASAP.  My brother has lost most of his vision in one eye now from high blood glucose.  And he has the tingling symptoms you described.  The tingling can progress to pain in time.  My brother chose to ignore his diabetes and is paying the price for it.  He is doing better at it now but the damage is done. Yes, B-12 deficiency can cause those kind of nerve symptoms.  But if you have high blood sugar that is the more common cause.   Diabetes is not a rare condition.
    • I have been living in Ho Chi Minh City, Vietnam, for two years, and finding gluten-free food is proving more difficult than I thought, even if I am cooking my own food. Wheat flour, called "bot mi" in Vietnamese, seems to creep into a lot of stuff nowadays. What's more, manufacturers do not feel it is important to list bot mi in the ingredients on a food's packaging unless it is a principle ingredient in the food. In other words, soy sauces or wraps with just a tiny bit of wheat flour added to add a touch of thickness or pliability are not guaranteed to list the ingredient. For some genetic reason, Vietnamese people are not nearly as susceptible to food allergies as Westerners - it probably has something to do with exposure to less hygenic foodstuffs having built up an immunity over hundreds of years - so it is not really considered important to split hairs in that department over here. Anyway, I love rice paper but have often gotten glutened by it when I have it. Can any celiac who could tell if a product had gluten by more than just the ingredient list on the back let me know a definitively gluten-free rice paper brand? I know that very few rice paper brands actually list wheat flour in the ingredients, but I don't 100% trust the ingredients list for products made by Vietnamese companies. Call me paranoid. By the way, I have a neurological condition that irreversably breaks down my immune system when I ingest gluten, so I don't want to experiment with trial by fire here.
  • Upcoming Events

  • Blog Entries

  • Recent Status Updates

  • Who's Online (See full list)

  • Member Statistics

    • Total Members
      61,695
    • Most Online
      3,093

    Newest Member
    ToniaC
    Joined