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Titer Test And Celiac Disease Ige Response


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#1 Celiac Ninja

 
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Posted 23 December 2013 - 07:29 AM

I am Rh- and pregnant. Baby is doing fine; kicking, punching, rolling, growing. Have not had an ultrasound to check for swelling of the liver or heart yet. Will do soon.

 

My main interest here with this situation is this:

 

I had a titer test done to see my antibody response sensitivity results. My baby is more than likely O+. I am obviously O-. This is my second child, first was O+ and born perfectly, a natural healthy home birth with nothing wrong with him at all, of course he was the first and the immune system would more than likely not attack his blood cells. Second pregnancy is however the kicker. My husband and I do not plan on having another and are prepared to avoid a third pregnancy. So the focus here is on the titer test at hand.

 

The titer test checks the antibody response to a potential viral threat in the body (sometimes seen as the O+ blood of the baby). The test shows that it is the IgE that is being tested. The IgE is also one of two major white blood cell responses that are tested for in a celiac panel. In fact, my titer results came back that my white blood cell count is a little high and my red is low.The results of the antibody response were D8. I have had another titer done but must wait for results for 10 days. Which is a very low result, not enough to be concerned with the baby safety, if you disagree you need to do further research. I am concerned that the celiac immune response is affecting the titer test results. I am concerned that doctors will not do further research and push a pregnant woman and her baby too far and too fast into: induction, intervention, C-section, or worse. Causing an even GREATER risk of the baby's life than allowing the child at a titer level of D8 to reside in his safety and further develop under close monitoring by ultra sound and titer tests until he or she is fully developed and ready to enter the world through a vaginal birth. I say a vaginal birth because intervention often causes the mother's blood and baby's blood to mix and that is the danger at hand. If the blood mixes, mother's white blood cells could kill the baby's red blood cells, causing him to starve of oxygen and nutrients leading to a whole slew of serious health risks and possible death of the baby. Intervention at this time is NOT the answer of course, being the titer is so low.

 

I'm going into detail, but the main questionable problem I see is the same immune response of the IgE for both cases: celiac disease and titer test results.

 

Doctors have not done enough research to know how to answer this question: Is celiac disease affecting the IgE immune response or am I getting conclusive results from the titer test? Can I trust the titer test to be accurate? Accurate enough to risk my baby's life?

 

SO far my conclusion is: No.


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#2 pricklypear1971

 
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Posted 23 December 2013 - 09:18 AM

Have you tried contacting the University of Chicago Celiac Center via email with your questions? They may be able to point you to an expert who has death with this.
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Apparently there is nothing that cannot happen today. ~ Mark Twain

Probable Endometriosis, in remission from childbirth since 2002.
Hashimoto's DX 2005.
Gluten-Free since 6/2011.
DH (and therefore Celiac) dx from ND
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Responsive to iodine withdrawal for DH (see quote, above).

Genetic tests reveal half DQ2, half DQ8 - I'm a weird bird!

#3 Celiac Ninja

 
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Posted 26 December 2013 - 06:14 PM

I sent them an email, hope it gets to them soon. Got test results back and my D8 has skyrocketed to D64, although I have had several including one bad gluten reaction between those tests. I am very very sensitive to gluten and other things. Now I am informed that the area where my husband and I live can no longer accommodate such a high risk baby. We will be shipped out to Spokane WA. Sigh, I want more information before being rushed into something that could potentially be dangerous for me and the baby, besides my immune system reacting to his blood. For a child to die peacefully on his mother's breast would be a greater gift I could give him than to die stuck with drugs and tubes in a plastic case away from mom's touch. I don't want my child to be forced through this in his last days. Now we need some prayer from people who are dead serious that they care.


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