Get email alerts Get Celiac.com E-mail Alerts  




Celiac.com Sponsor:
Celiac.com Sponsor:




Ads by Google:






   Get email alerts  Subscribe to FREE Celiac.com email alerts

  • Announcements

    • admin

      Frequently Asked Questions About Celiac Disease   09/30/2015

      This Celiac.com FAQ on celiac disease will guide you to all of the basic information you will need to know about the disease, its diagnosis, testing methods, a gluten-free diet, etc.   Subscribe to FREE Celiac.com email alerts What are the major symptoms of celiac disease? Celiac Disease Symptoms What testing is available for celiac disease? - list blood tests, endo with biopsy, genetic test and enterolab (not diagnostic) Celiac Disease Screening Interpretation of Celiac Disease Blood Test Results Can I be tested even though I am eating gluten free? How long must gluten be taken for the serological tests to be meaningful? The Gluten-Free Diet 101 - A Beginner's Guide to Going Gluten-Free Is celiac inherited? Should my children be tested? Ten Facts About Celiac Disease Genetic Testing Is there a link between celiac and other autoimmune diseases? Celiac Disease Research: Associated Diseases and Disorders Is there a list of gluten foods to avoid? Unsafe Gluten-Free Food List (Unsafe Ingredients) Is there a list of gluten free foods? Safe Gluten-Free Food List (Safe Ingredients) Gluten-Free Alcoholic Beverages Distilled Spirits (Grain Alcohols) and Vinegar: Are they Gluten-Free? Where does gluten hide? Additional Things to Beware of to Maintain a 100% Gluten-Free Diet Free recipes: Gluten-Free Recipes Where can I buy gluten-free stuff? Support this site by shopping at The Celiac.com Store.

Help In Interpreting Biopsy Results - Please
0

4 posts in this topic

Hi all, I was wondering if someone can help me in interpreting my EGD biopsy results from 2 weeks ago. My doc just called me yesterday and has asked me to stay away from wheat, milk and related products. Quite honestly, I am a bit shocked. 

 

Feb 2014: Celiac Lab came back as negative in all categories but in my IBD expanded profile showed the ALCA was high with everything else in range.

 

April 2014: Biopsy reads as follows "Duodenal mucosa including bulb mucosa with brunners glands, showing elongated villous architecture. There is a mild increase in the inter epithelial T Cells (CD3) in duodenal epithelium. Gastric Metaplasia not seen in duodenal epithelium". 

 

What does this mean? Is this a cause for concern? Do i need to go on a gluten free diet? I don't have ongoing symptoms on bloating etc...

 

Looking forward to your valuable input. 

0

Share this post


Link to post
Share on other sites


Ads by Google:

Welcome G!

 

In simple terms you have damage in your small intestine that has likely been caused by gluten and/or dairy in your diet.

 

Make sure you had all of these blood tests:

 

Total Serum IgA

tTG-IgA

tTG-IgG

EMA-IgA

DGP-IgA

DGP-IgG

 

Also helpful is blood test for nutrients as malabsorption can be an issue with the damage found during your endoscopy:

 

B6, B12, D, K, Iron, Ferritin, Copper and Zinc

CMP and CBC

 

Additionally, in this case the genetic test for genes associated with Celiac Disease could be helpful...having the genes does not mean a person will develop celiac...but genes plus small intestine damage is telling.

 

Not everyone with Celiac Disease has obvious digestive distress...there are over 300 symptoms associated with Celiac Disease.

 

If you are certain you have had all the celiac antibody tests listed above, it is indeed time to remove all gluten and dairy.  If this is Celiac Disease, you will likely get dairy products back after your intestinal damage has healed.

 

Hang in there :)

0

Share this post


Link to post
Share on other sites

Welcome G!

 

In simple terms you have damage in your small intestine that has likely been caused by gluten and/or dairy in your diet.

 

Make sure you had all of these blood tests:

 

Total Serum IgA

tTG-IgA

tTG-IgG

EMA-IgA

DGP-IgA

DGP-IgG

 

Also helpful is blood test for nutrients as malabsorption can be an issue with the damage found during your endoscopy:

 

B6, B12, D, K, Iron, Ferritin, Copper and Zinc

CMP and CBC

 

Additionally, in this case the genetic test for genes associated with Celiac Disease could be helpful...having the genes does not mean a person will develop celiac...but genes plus small intestine damage is telling.

 

Not everyone with Celiac Disease has obvious digestive distress...there are over 300 symptoms associated with Celiac Disease.

 

If you are certain you have had all the celiac antibody tests listed above, it is indeed time to remove all gluten and dairy.  If this is Celiac Disease, you will likely get dairy products back after your intestinal damage has healed.

 

Hang in there :)

Hi Lisa

Thank you for your prompt response. I have completed all the following tests...CBC,CMP, Total Serum IgA, tTG-IgA, tTG-IgG, EMA-IgA, DGP-IgA, DGP-IgG.

Further I am vitamin B-12 and D deficient so we keep testing that every 6 months. The deficiency is quite common from my country of origin, so my doc was not too concerned about that. I have had 5 EGD's from 2005 to now and none of them showed this elongated villi. Not sure how this can happen suddenly.

Anyhow, I will request my doc to do some further evaluation. My biopsy report does not say anything like March 2-3-4 or Celiac Intolerance etc...i would assume something should have been written if the diagnosis was confirmatory in nature. 

Thank you once again.

0

Share this post


Link to post
Share on other sites

Hi Lisa

Thank you for your prompt response. I have completed all the following tests...CBC,CMP, Total Serum IgA, tTG-IgA, tTG-IgG, EMA-IgA, DGP-IgA, DGP-IgG.

Further I am vitamin B-12 and D deficient so we keep testing that every 6 months. The deficiency is quite common from my country of origin, so my doc was not too concerned about that. I have had 5 EGD's from 2005 to now and none of them showed this elongated villi. Not sure how this can happen suddenly.

Anyhow, I will request my doc to do some further evaluation. My biopsy report does not say anything like March 2-3-4 or Celiac Intolerance etc...i would assume something should have been written if the diagnosis was confirmatory in nature. 

Thank you once again.

 

If your vitamin deficiencies improve on a gluten free diet -- that is another piece of the puzzle.

 

Would be nice to have a certain answer -- but this may be one of those that removing gluten is what is needed to confirm you have an issue with gluten.  Hope that makes sense.

 

Take a read through this thread...it has wonderful info to help fast forward the learning curve involved with completely removing gluten from your diet:

 

http://www.celiac.com/gluten-free/topic/91878-newbie-info-101/

0

Share this post


Link to post
Share on other sites

Create an account or sign in to comment

You need to be a member in order to leave a comment

Create an account

Sign up for a new account in our community. It's easy!


Register a new account

Sign in

Already have an account? Sign in here.


Sign In Now
0