Get email alerts Get Celiac.com E-mail Alerts  




Celiac.com Sponsor:
Celiac.com Sponsor:




Ads by Google:






   Get email alerts  Subscribe to FREE Celiac.com email alerts

  • Announcements

    • admin

      Frequently Asked Questions About Celiac Disease   09/30/2015

      This Celiac.com FAQ on celiac disease will guide you to all of the basic information you will need to know about the disease, its diagnosis, testing methods, a gluten-free diet, etc.   Subscribe to FREE Celiac.com email alerts What are the major symptoms of celiac disease? Celiac Disease Symptoms What testing is available for celiac disease? - list blood tests, endo with biopsy, genetic test and enterolab (not diagnostic) Celiac Disease Screening Interpretation of Celiac Disease Blood Test Results Can I be tested even though I am eating gluten free? How long must gluten be taken for the serological tests to be meaningful? The Gluten-Free Diet 101 - A Beginner's Guide to Going Gluten-Free Is celiac inherited? Should my children be tested? Ten Facts About Celiac Disease Genetic Testing Is there a link between celiac and other autoimmune diseases? Celiac Disease Research: Associated Diseases and Disorders Is there a list of gluten foods to avoid? Unsafe Gluten-Free Food List (Unsafe Ingredients) Is there a list of gluten free foods? Safe Gluten-Free Food List (Safe Ingredients) Gluten-Free Alcoholic Beverages Distilled Spirits (Grain Alcohols) and Vinegar: Are they Gluten-Free? Where does gluten hide? Additional Things to Beware of to Maintain a 100% Gluten-Free Diet Free recipes: Gluten-Free Recipes Where can I buy gluten-free stuff? Support this site by shopping at The Celiac.com Store.

Celiac Blood Testing
0

4 posts in this topic

Hi All,

I am new to the forum.  I have 2 children with GI issues and I myself have had IBS type symptoms most my life.   We've had blood work celiac panels run on both of my children and told they were negative with no need for genetic testing.  My dd also had an endoscopy done at Mayo Clinic in Rochester and from all those results, I see they did not do any separate biopsies for celiac.  When I talked to the nurse about it later because dd was still having symptoms, I was told that since there was no sign of inflammation or damage, they did not need to do the biospies for celiac.   Not sure what I think about that.  My gut tells me they can not see that well to know for sure, but wanted the groups advice on all of this.     OK, so my dd's GI history is MSPI as a baby, then reflux and regurgitation of foods possibly related to histamine intolerances, and also possible fructose malabsorption. She's also has constipation issues since she was a baby.   Recently diagnosed with SIBO at age 8 but since the methane gasses were higher toward the end of the breath test, doc thought it was being caused by her constipation.    Her vitamin B-12 was over 1500.   No exact number was given, just over 1500.     DD has aversion to almost all fruits and veggies.   She'll eat strawberries, green beans, some lettuce and cooked carrots.   Sometimes some applesauce or fresh apples but we are pealing the skins to make easier to digest. .  She also has texture issues but is very smart, top of her class.   Was not growing at one time around age 2, but now is growing and gaining weight but on the lower end of the curve for her age but looks healthy.    So  here are my dd's blood test results.  She was almost 7 years at the time.   Immunoglobulin A Serum =101  ( range is 33-200);

Gliadin Peptide Antibody, IgA  = 2  (range 0-19); tTG Antibody, IgA  =4  (range 0-19).      Also, my son's Celiac results were almost identical to my daughters and the same testing panel was done on him.   Both tests were completed by ARUP labs out of Salt Lake City, UT.      

   Any advise on these test results would be appreciated.   Specific questions being do you all think ARUP's panel is complete or a good one.  Do those blood test results look questionable at all for possible celiac disease or do they looked strongly negative.   Just trying to put this to rest as FP doc keeps telling us to avoid the wheat, but don't want to take her off it, if more testing should be completed.      

0

Share this post


Link to post
Share on other sites


First thought.

Have you been properly tested for celiac disease?

Other thoughts:

It is difficult sometimes kids take longer to test positive and do agree that samples should have been taken and sent to the lab during the endoscopy...sadly not many doctors want to move forward with celiac diagnosis once blood is negative.

Did either child have a DGP-IgG?

0

Share this post


Link to post
Share on other sites

Thanks Gottaski,  No, I have not been tested myself for Celiac.    I've never had an endoscopy.  Years ago I had a sigmoidoscopy, BE series and upper GI Barium study but that was it. I was told all was fine with these tests and  I was told I had IBS with no advice. Just avoid gassy foods.       Neither kids have had the DGP-IgG test done.   Do you know which lab runs that test in the US.   All the hospitals in our city use ARUP out of Salt Lake City.    Not sure if ARUP does that test.    It seems like the GI docs in our town don't do celiac biospies very often.  I've just heard stories of people having endoscopies and no biopsies for celiac being done.    That's why we went to Mayo with my daughter.  They are supposed to be the best and then they didn't even do the biopsies.     What are your thoughts on the results I listed??   I don't even know what the Immuglobulin A test is for?   Is that to show if a person if IGG or IGA deficient???   No one explained any of the blood test results to me.   Just that the kids were negative.   Don't get to talk to doctor about results.   The nurses always just call back and say they are negative and then they don't know the specifics about the tests.   Very frustrating....  

0

Share this post


Link to post
Share on other sites

Oh goodness.

Yes, the Immuglobulin A is often referred to as "Total Serum IgA" and is a control test to see if one is IgA deficient. If deficient then some docs will order the IgG based celiac antibody tests.

Here's one problem....some, especially young kids can be positive on one of any antibody tests or all of them. I always recommend kids with obvious symptoms &/or family history of celiac disease be tested with the complete celiac antibody panel.

I'll add the complete list when I get back to my laptop....on mobile version just now.

Hang in there...keep reading.

I would suggest you get a complete antibody panel yourself. Your primary can order it.

0

Share this post


Link to post
Share on other sites

Create an account or sign in to comment

You need to be a member in order to leave a comment

Create an account

Sign up for a new account in our community. It's easy!


Register a new account

Sign in

Already have an account? Sign in here.


Sign In Now
0

  • Forum Statistics

    • Total Topics
      102,702
    • Total Posts
      914,493
  • Topics

  • Posts

    • cadbury eggs?
      According to last year's Coeliac UK Food and Drink Directory they both are safe foods for us - I haven't got this year's though.   I do react  if I am glutened but have never had any problem with Creme Eggs - and  I bought some just after Christmas.  If you are anywhere else in the world maybe they change the ingredients but I would say you are fine in the UK..     
    • Glucose Tablets
      According to RelioOn, they do offer Gluten free glucose tablets website info   Lar
    • Do this, scientists! (experiment to confirm/deny the existence of "leaky gut")
      Good idea! Add also the lactulose - mannitol test, to confirm they are/are not experiencing leakyness in the gut, then correlate the results with the symptoms (obviously digestive symptoms would have to be excluded, because diarrhea and bloating will probably be present anyway, due to having damaged intestines). You see, ironically it would be "gluten-free challenge", because possibly systemic symptoms ("leaky gut syndrome")  and GI symptoms start after going IV fluids -> gluten-free (instead of "gluten challenge", which would be gluten-free -> gluten).
             
    • "Pre-Celiac" & scared
      PPIs should not affect your digestion of gluten one way or another. Many folks with celiac disease may have villous damage without obvious symptoms. Others eventually get symptoms after the disease is "activated," but exactly how or why this happens is not yet clearly understood. Biopsies are generally done after someone has symptoms, and likely already has villous damage, so I would imagine your doctor must be necessarily a bit vague about whether you might have "inactive" or "active" celiac disease. The gold standard is to get a biopsy while still eating gluten, and then another after being on a gluten-free diet for some time, to assess whether you heal without gluten in your system. Positive genes and blood work, AND villous atrophy would seem like fairly strong evidence, but that's up to your doctor to determine. If you feel comfortable sharing your test results on the forum, some folks here can give you their two cents. But listen to your doctor! Glutenease might help your digestion, but if you have an autoimmune reaction to gluten, it won't prevent the possible damage that comes with gluten mistakes. Research on l-glutamine is somewhat supportive for healing, but it's not a panacea.  You will read about various levels of sensitivity and prudence here and elsewhere. Eventually you'll come up with a plan that you consider is "safe," but hopefully will still let you get out in the world. Read up on gluten-free groceries and how to deal with restaurants safely, and you ought to be able to find a happy "middle-path" between prudence and paranoia. I'm one of the fairly sensitive/paranoid types at this point in my life. I personally don't worry too much about possibly breathing in gluten, but on the other hand I wouldn't eat anything that's been out where flour is in the air. Nor would I use a shared toaster or fryer. Again, it's important that you form a lifestyle approach that is informed about the risks but still a good life! Most importantly, work with your medical team to determine if you in fact have celiac disease.
    • Second Panel has come back...advice?
      We are utilizing the "our kitchen is completely gluten free" and DEFINITELY checking every label every time methods. SO glad to hear my DGP should drop!!!! 
  • Upcoming Events

  • Blog Entries

  • Recent Status Updates

  • Who's Online (See full list)

  • Member Statistics

    • Total Members
      59,739
    • Most Online
      1,763

    Newest Member
    larnotlars
    Joined