Jump to content
This site uses cookies. Continued use is acceptance of our Terms of Use and Privacy Policy. More Info... ×

  • Welcome to Celiac.com!

    You have found your celiac tribe! Join us and ask questions in our forum, share your story, and connect with others.



  • Celiac.com Sponsor (A1):

    Celiac.com Sponsor (A1-M):

  • Get Celiac.com Updates:
    Support Celiac.com!
    eNewsletter
    Donate

Dq8

bridee

Recommended Posts

bridee Rookie
bridee
Posted

My daughter has just tested positive to the gene DQ8 (negative to DQ2).  We are waiting for an appointment with a specialists (her symptoms are episodes of blurred vision, low iron, stomach pain and unusual acid wear on her teeth) but on another forum I had someone tell me his doctor said DQ8 by itself was incompatible with celiac disease.  So was just wondering does any here have DQ8 only and have diagnosed celiac disease?

Link to comment
Share on other sites
Celiac.com Sponsor (A8):
Celiac.com Sponsor (A8):

Celiac.com Sponsor (A8-M):


kareng Grand Master
kareng
Posted

Open Original Shared Link

 

it is a Celiac gene.  Having the gene alone, does not make a Celiac diagnosis. About 30 % of people have one of the genes for Celiac.  But only 1% have Celiac.

Link to comment
Share on other sites
bridee Rookie
bridee
  • Author
Posted

I now having the gene does not necessarily mean you have celiac but this person had been told having DQ8 only means you can never get celiac disease.  My understanding was this gene is rarer but you can still become celiac with it.

Link to comment
Share on other sites
kareng Grand Master
kareng
Posted

I now having the gene does not necessarily mean you have celiac but this person had been told having DQ8 only means you can never get celiac disease.  My understanding was this gene is rarer but you can still become celiac with it.

 

I would go with the Celiac experts on this one.

From my link- 

 

"Two genes are responsible for celiac disease (HLA-DQ2 & HLA-DQ8). If you have either of them, then you have the potential for the disease to activate at any age. "

Link to comment
Share on other sites
LauraTX Rising Star
LauraTX
Posted

The person whose post you read online was incorrect in their understanding.  It is the rarer of the two genes, as you said. Check out the info Karen linked above.

 

That is why we really like to link to reputable sources on here, because when you read something online you have to be weary about there that information came from.  On here we will correct bad info given by others, but people are human and who knows, that original guy on the other forum could have just made a typo.  Hopefully... if not, give him that link Karen gave you, haha.

Link to comment
Share on other sites
  • 3 weeks later...
VeggieGal Contributor
VeggieGal
Posted

Hi, I have the DQ8 gene and was diagnosed with celiac disease 2 years ago. In fact blurred vision and anemia has been my worse symptoms along with achey arms, bloating and dh.

Edit: Oh and brainfog...I forgot that one☺

Link to comment
Share on other sites
1desperateladysaved Proficient
1desperateladysaved
Posted

I have DQ8 and have celiac also!

 

Dee

Link to comment
Share on other sites
Celiac.com Sponsor (A8):
Celiac.com Sponsor (A8):

Celiac.com Sponsor (A8-M):


Archived

This topic is now archived and is closed to further replies.

Go to topic listing
  • Celiac.com Sponsor (A19):


  • Member Statistics

    • Total Members
      121,213
    • Most Online (within 30 mins)
      7,748
    marimom
    Newest Member
    marimom
    Joined
  • Celiac.com Sponsor (A20):

  • Forum Statistics

    • Total Topics
      120.3k
    • Total Posts
      1m
  • Celiac.com Sponsor (A22):



  • Celiac.com Sponsor (A21):


  • Upcoming Events

  • Posts

    • trents
      Trying to read my lab results

      By trents · Posted

      You have three celiac disease specific antibody tests that are positive: Endomysial  Antibody IGA (aka, EMA), tTG-IGA, and tTG_IGG. Furthermore, your Immunoglobulin A at 55 is low, meaning you are IGA deficient. This one is not an antibody test for celaic disease per se but a measure of "total IGA" levels and if low (yours is low) it can suppress the individual antibody scores and even cause false negatives. So, yes, it definitely looks like you have celiac disease.   Do not yet begin a gluten free diet as your physician may refer you to a GI doc for an endoscopy/biopsy of the small bowel lining for confirmation of the antibody testing. This may help:   
    • Bayb
      Trying to read my lab results

      By Bayb · Posted

      Hi, I received my labs via email yesterday and have not heard back from my doctor yet. Can anyone tell me if these results indicate I have Celiac?      Endomysial Antibody IgAPositive  Ft-Transglutaminase (tTG) IgA6  H0-3 (U/mL) - Negative 0 - 3 - Weak Positive 4 - 10 - Positive >10 - Tissue Transglutaminase (tTG) has been identified as the endomysial antigen. Studies have demonstrated that endomysial IgA antibodies have over 99% specificity for gluten-sensitive enteropathy. FImmunoglobulin A, Qn, Serum55  L87-352 (mg/dL) Ft-Transglutaminase (tTG) IgG183  H0-5 (U/mL) - Negative 0 - 5 - Weak Positive 6 - 9 - Positive >9
    • Aussienae
      Constant low back, abdominal and pelvic pain!

      By Aussienae · Posted

      Mine is definitely triggered by inflammation and stress! I do also have arthritis in my spine, but the pain is more in my pelvic area. Im sure i have other food intolerances or other autoimmune isues but the more I focus on it and see doctor after doctor, it just gets worse.  Best thing is get of Gluten! (I also avoid lactose). Try to limit stress and anything that causes inflammation in your body.
    • ButWhatCanIEat
      Constant low back, abdominal and pelvic pain!

      By ButWhatCanIEat · Posted

      Good morning,   I got an email about replies to this post. Some of my doctors had blamed a slipped disc for the pain I had and that contributes, but after meeting with a gastroenterologist AGAIN and trying some lifestyle modifications, I found out I have IBS and can't tolerate corn or excessive fructose to any degree. Cutting out corn AFTER having cut out all gluten containing products was a real pain but I feel much better now!
    • trents
      Isolated DPG-Iga

      By trents · Posted

      So, I contacted Scott Adams, the author of that article and also the creator/admin of this website, and pointed out to him the need to clarify the information in the paragraph in question. He has now updated the paragraph and it is clear that the DGP-IGA does serve the purpose of circumventing the false negatives that IGA deficiencies can generate in the tTG-IGA antibody test.
×
×
  • Create New...