Jump to content
This site uses cookies. Continued use is acceptance of our Terms of Use and Privacy Policy. More Info... ×

  • Welcome to Celiac.com!

    You have found your celiac tribe! Join us and ask questions in our forum, share your story, and connect with others.



  • Celiac.com Sponsor (A1):

    Celiac.com Sponsor (A1-M):

  • Get Celiac.com Updates:
    Support Celiac.com!
    eNewsletter
    Donate

Iga Deficient Test Results

Haschmid9

Recommended Posts

Haschmid9 Newbie
Haschmid9
Posted

I daughter was recently diagnosed with celiac disease so I was tested last week. My results showed that I am IgA deficient but my other test (transglutaminase) came back normal. What does this mean about my results? I heard being IgA deficient can sometimes mess provide a false negative result. Should I encourage my doctor to do more tests?

Link to comment
Share on other sites
Celiac.com Sponsor (A8):
Celiac.com Sponsor (A8):

Celiac.com Sponsor (A8-M):


LauraTX Rising Star
LauraTX
Posted

Yes, a low IgA total means your transglutaminase IgA test could potentially be a false negative.  Definitely encourage your doctor to do more tests, and follow up with your primary care doctor on your IgA levels being low, to make sure you don't need that looked into.  And if you have other children, encourage them to all get testing done.  Here is a list of tests you can ask for.  If your IgG is normal, you can rely on those instead of the IgA versions of the tests.  Definitely make sure they pull a total IgG to make sure they are valid.

 

-tTG IgA and tTG IgG
-DGP IgA and DGP IgG
-EMA IgA 
-total serum IgA and IgG (control test)
-AGA IGA and AGA IgG - older and less reliable tests largely replace by the DGP tests
-endoscopic biopsy - make sure at least 6 samples are taken

 

Welcome to the forum and let us know how it goes! :)

Link to comment
Share on other sites
  • 2 weeks later...
Zebra007 Contributor
Zebra007
Posted

Yes, a low IgA total means your transglutaminase IgA test could potentially be a false negative.  Definitely encourage your doctor to do more tests, and follow up with your primary care doctor on your IgA levels being low, to make sure you don't need that looked into.  And if you have other children, encourage them to all get testing done.  Here is a list of tests you can ask for.  If your IgG is normal, you can rely on those instead of the IgA versions of the tests.  Definitely make sure they pull a total IgG to make sure they are valid.

 

-tTG IgA and tTG IgG
-DGP IgA and DGP IgG
-EMA IgA 
-total serum IgA and IgG (control test)
-AGA IGA and AGA IgG - older and less reliable tests largely replace by the DGP tests
-endoscopic biopsy - make sure at least 6 samples are taken

 

Welcome to the forum and let us know how it goes! :)

Hi Laure, I don't have a clue what any of this means...and I think I need to  :) could you suggest a link that explains it easily..thank you.  

Link to comment
Share on other sites
cyclinglady Grand Master
cyclinglady
Posted

The University of Chicago has an excellent celiac website. They are one of the leading research hospitals. Your local library should have some books on celiac disease too.

Link to comment
Share on other sites
nvsmom Community Regular
nvsmom
Posted

This report is quite good too: Open Original Shared Link

Link to comment
Share on other sites
LauraTX Rising Star
LauraTX
Posted

Hi Laure, I don't have a clue what any of this means...and I think I need to  :) could you suggest a link that explains it easily..thank you.  

 

Lets see where did those links go....all the factsheets from Univ of Chicago are really helpful.

This explains all the antibody blood tests: Open Original Shared Link

Genetic tests: Open Original Shared Link

Endoscopy and 5-6 biopsy sites:  Open Original Shared Link

 

In fact, anyone who is needing to get info to their doctor on how to diagnose will highly benefit from just printing those 3 out and getting them to their doctor.  On the Open Original Shared Link website, some of the better, more technical info is under the "Medical professionals" column.  So, depending on what labs are available in a person's area, what the doctor feels comfortable doing, etc, it can really help to have that big list and the factsheets.

Link to comment
Share on other sites
Zebra007 Contributor
Zebra007
Posted

Thank you all very much I will start looking at this...

 

There is so much that I don't know about this disease, rashes, pains in joints etc, which is why I need to stick around and become more informed.

Link to comment
Share on other sites
Celiac.com Sponsor (A8):
Celiac.com Sponsor (A8):

Celiac.com Sponsor (A8-M):


Archived

This topic is now archived and is closed to further replies.

Go to topic listing
  • Celiac.com Sponsor (A19):


  • Member Statistics

    • Total Members
      121,215
    • Most Online (within 30 mins)
      7,748
    Julez13
    Newest Member
    Julez13
    Joined
  • Celiac.com Sponsor (A20):

  • Forum Statistics

    • Total Topics
      120.3k
    • Total Posts
      1m
  • Celiac.com Sponsor (A22):



  • Celiac.com Sponsor (A21):


  • Upcoming Events

  • Posts

    • mishyj
      Why?

      By mishyj · Posted

      Perhaps I should also have said that in addition to showing a very high response to gluten, her stool study showed that she had extreme reactions to everything achievement on it long course of microbials to treat that.
    • mishyj
      Why?

      By mishyj · Posted

      My daughter has celiac disease and has had for a long time. She fell loses strictly gluten-free diet and recently got rid of all cutting boards in any gluten in her house at all. She just had a stool test and it came back showing of gigantic response to gluten in her diet. What could be going on since she doesn't eat any gluten and is very careful about any kind of hidden glue? Help!
    • cristiana
      Constant low back, abdominal and pelvic pain!

      By cristiana · Posted

      I think sometimes the pain described here can be a result of a sort of 'perfect storm' of contributing factors.  Recently I had an appalling bout of lower back pain, lower burning gut pain and what felt like cramps.  I then started to think about what could have caused it and I realised it was several things that had set it off: I'd been carrying heavy luggage (back strain); I had been sitting down in a car for too long and wearing a tight belt (I have pudendal nerve issues and sacroiliac issues and this exacerbates the pain), and I had bloating and burning pain in my colon caused by eating too much soy, latte and caffeine, I guess putting further pressure in the lower abdomen.  I had this same pain prior to my diagnosis and a couple of years post-diagnosis, I'd quite forgotten how unpleasant it was. 
    • cristiana
      Have this rash forming on the back of my legs. Looking for relief outside of going to the doctor.

      By cristiana · Posted

      HI @Kirbyqueen That's great news your insurance will be kicking in soon.  Sorry to see that you have been dealing with this for six months now, but I do hope you have managed to find some relief with some of the suggestions in the meantime. Perhaps come back and let us know what the doctor says. Cristiana
    • Scott Adams
      Trying to read my lab results

      By Scott Adams · Posted

      I agree, and hopefully your doctor will contact you soon about the next step, which will likely be an endoscopy to confirm your diagnosis. Do you have celiac disease symptoms? 
×
×
  • Create New...