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      Frequently Asked Questions About Celiac Disease   09/30/2015

      This Celiac.com FAQ on celiac disease will guide you to all of the basic information you will need to know about the disease, its diagnosis, testing methods, a gluten-free diet, etc.   Subscribe to FREE Celiac.com email alerts What are the major symptoms of celiac disease? Celiac Disease Symptoms What testing is available for celiac disease? - list blood tests, endo with biopsy, genetic test and enterolab (not diagnostic) Celiac Disease Screening Interpretation of Celiac Disease Blood Test Results Can I be tested even though I am eating gluten free? How long must gluten be taken for the serological tests to be meaningful? The Gluten-Free Diet 101 - A Beginner's Guide to Going Gluten-Free Is celiac inherited? Should my children be tested? Ten Facts About Celiac Disease Genetic Testing Is there a link between celiac and other autoimmune diseases? Celiac Disease Research: Associated Diseases and Disorders Is there a list of gluten foods to avoid? Unsafe Gluten-Free Food List (Unsafe Ingredients) Is there a list of gluten free foods? Safe Gluten-Free Food List (Safe Ingredients) Gluten-Free Alcoholic Beverages Distilled Spirits (Grain Alcohols) and Vinegar: Are they Gluten-Free? Where does gluten hide? Additional Things to Beware of to Maintain a 100% Gluten-Free Diet Free recipes: Gluten-Free Recipes Where can I buy gluten-free stuff? Support this site by shopping at The Celiac.com Store.

I Have The Gene
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3 posts in this topic

Hi, I am having my son (whose father also has celiac) tested this Thurs. and my daughter (different dad) tested next week....what are the statistics for offspring of positive gene carrying parents. Obviously my son is in trouble...but what about with one parent? thanks, Paula

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Paula,

If I am remembering 7th-grade science correctly, here are the theoretical odds:

Parent 1: TWO copies \ ------> 100% chance of inheriting TWO copies

Parent 2: TWO copies /

Parent 1: TWO copies \ ------> 50% chance of inheriting TWO copies

Parent 2: ONE copy.... / ------> 50% chance of inheriting ONE copy

Parent 1: ONE copy \ ------> 25% chance of inheriting TWO copies

(.............................) > ------> 50% chance of inheriting ONE copy

Parent 2: ONE copy / ------> 25% chance of inheriting ZERO copies

Parent 1: ONE copy.... \ ------> 50% chance of inheriting ONE copy

Parent 2: ZERO copies / ------> 50% chance of inheriting ZERO copies

What I don't know (and I'm not sure the experts know either) is what, if any, difference carrying ONE vs. TWO copies makes in the likelihood of actually developing gluten intolerance. And there MAY be a chance, depending on your genetic makeup and his dad's, that your son might have escaped inheriting even a single copy of the gene! Your daughter most likely has better odds since her father is not known to have celiac disease, but I can't be sure of this. I hope your kids get lucky and don't carry the gene at all!

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Thanks Sarah. Unfortunately, my son is soooo symptomatic! However, he is 17 so changing diet may not be something he will do until he is on his death bed! My 15 yr. old has no symptoms however my 10 yr old does...crazy! thanks, Paula

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