Get email alerts Get Celiac.com E-mail Alerts  




Celiac.com Sponsor:
Celiac.com Sponsor:




Ads by Google:






   Get email alerts  Subscribe to FREE Celiac.com email alerts

Ttg Below Normal; Biopsy Shows Inflammation
0

3 posts in this topic

:blink:

I've been a lurker for the past couple weeks, but now that we have test results, here's the question:

Does anyone know what it could mean if the anti-tissue transglutaminase autobody test (tTG) is below normal? (Reference range is 4 to 6, her result is 2.0).

My 26Y wife has been having severe abdominal pain for over a year, but it has been increasing with severe intensity. A biopsy has confirmed inflammation -- but the villi (where the biopsy was taken, at least) are intact. A barium swallow has indicated nothing out of the ordinary.

I'm guessing that if the autoantibody test is below normal, perhaps she doesn't produce IgA, and therefore it shows a below-normal range? Does this sound right?

She doesn't see the doctor until January. Would a gluten-free diet be suggested?

Any ideas or experiences would be greatly appreciated.

Edited by JasonJayhawk
0

Share this post


Link to post
Share on other sites


Ads by Google:

Welcome! I am fairly new myself.

I'll give my input but hopefully some others with more knowledge will chime in.

I am going to agree with what you said about the possibility of her being IgA deficient. Did she also have a total serum IgA done with the other tests? That will measure whether or not she has a normal amount of antibodies. She should ask her doctor about this.

Did she have other tests done at the time?

If the doctor plans on doing more testing she should probably stay on her regular diet. But others will tell you that the best way to know if going gluten-free will help is to do it. Just not before more diagnostic testing, otherwise the results won't be accurate.

As I said, you'll probably get more info from others here. Good luck to both of you! It's great that you are here trying to get info to help her.

Channon

0

Share this post


Link to post
Share on other sites
:blink:

I've been a lurker for the past couple weeks, but now that we have test results, here's the question:

Does anyone know what it could mean if the anti-tissue transglutaminase autobody test (tTG) is below normal? (Reference range is 4 to 6, her result is 2.0).

My 26Y wife has been having severe abdominal pain for over a year, but it has been increasing with severe intensity. A biospy has confirmed inflammation -- but the villi (where the biopsy was taken, at least) are intact. A barium swallow has indicated nothing out of the ordinary.

I'm guessing that if the autoantibody test is below normal, perhaps she doesn't produce IgA, and therefore it shows a below-normal range? Does this sound right?

She doesn't see the doctor until January. Would a gluten-free diet be suggested?

Any ideas or experiences would be greatly appreciated.

Its possible she could have an IgA deficiency. She should be tested for that. If you are looking for a definate diagnosis you should not start the diet until all testing is complete otherwise you may be left with unanswered questions. The response to the diet will definately give you some kind of answer but January is not that far away. If she is not too ill she can just enjoy the holidays eating normally and get the tests completed in January. If the tests are inconclusive or negative I'd still try the diet since there is inflamation and the tests arent always accurate.

0

Share this post


Link to post
Share on other sites

Create an account or sign in to comment

You need to be a member in order to leave a comment

Create an account

Sign up for a new account in our community. It's easy!


Register a new account

Sign in

Already have an account? Sign in here.


Sign In Now
0

  • Forum Statistics

    • Total Topics
      104,688
    • Total Posts
      921,755
  • Topics

  • Posts

    • Yeah I ended up allergic to corn, olives, sesame, whey, and peanuts and intolerant to dairy, soy, yeast, enzyme issues with breaking down meats, and egg yolks, along with extreme bloat with any kind of carbs/sugars in moderate amounts. And very adverse reactions to certain artificial sweeteners. So your not alone in all the other issues cropping up, it happens as our bodies adjust.  I eat a bunch of stir frys with veggies, egg whites, plenty of  avocados, and toasted and raw forms of almonds, coconut, cashews, walnuts, hemp seeds, pumpkin seeds, flax seeds, sancha inchi seeds, chia seeds, and sunflower seeds in all forms including making them into butters, spreads, and incorporating them into sauces.   Most meals are forms of soups, omelettes, and stir frys. I do the seeds and nuts on rotation same with my veggies and snack on fruits in small amounts along with some homemade baked goods I make for markets. I do suggest a rotation of foods, my dietician said I need to rotate my foods to prevent more issues, making sure I am off one one for at least 7-14 days at a time completely. I find changing up the spices and rotating my cuisine base works well. I also make puddings, and protein shakes along with nut/seed milks, and different bases and extract flavorings to get my random cravings Taken care of. Guess take what you can from this and and see how it can help you,    As to the tinging, I ended up with both B vitamin and magnesium deficiency issues, the magnesium one caused a fire like tingling in my arms, legs and back, along with muscle pain. Ended up on a doctors best powder form of it so I can dose it out right, and found epsom salt bathes helped.  
    • Hi, I've gained so much knowledge on this forum over the past few months, which I am so thankful for. I can see how much hell people are going through with this disease and it's so lovely to see how much support and advice people give to others on here. I'd like a little bit of reassurance and advice myself from anyone that can help. I've been gluten free for six months. Two weeks after going gluten free I realised I also had a problem with corn so cut out processed food. Over the following weeks and months I continually had problems with food; fruit, dairy, a lot of vegetables, nuts, soya....it's basically dwindled down to just eating potatoes (not white potatoes), cucumber, lettuce, small amounts of red onion, spring onion, sprouts and beetroot. There may be more things I could be okay with but to be honest I'm too scared to try.  Is this all normal? Am I an extreme case? I've been taking some digestive enzymes and probiotics for about six weeks, my acid reflux has dramatically decreased but I always have a lot of loud noises going on in my guts, I'm guessing this is the probiotics working.  I've lost nearly 3st in weight since this started - which I'm not complaining about as I was overweight due to thyroid problems. I've had loads of blood tests done recently, all organs are working 'great' according to my doctor, the only thing they've picked up on is ketones, I seem to be having a glucose problem, which might explain my exhaustion and weight loss. I also have permanent numbness and sometimes tingling in one of my legs and sometimes hands and one shoulder, I thought it could have vitamin B12 deficiency but that's okay according to blood tests. I would be greatful for any replies. Thanks for reading.
    • Hi everyone, I am doing job in restaurant at evening 5 to 12 during working hours no time to do a dinner. I'm thinking to make a shake but don't know the gluten free vitamin or supplement brand which one is good for me and easily available in Berlin Germany to make me fit cause last one week i feel weak. I'm 28 year old. Sincerely
    • Hey there just wanted to warn anyone that has other allergies- these crackers may not be a good choice! I'm mildly sensitive to MSG- I only react if there's a giant amount like in Chinese food or Ramen noodles, etc.  I literally have a to eat TONS of a the offending food before reacting.  Anyway, I was excited to try these Trader Joes pumpkin crackers, kept hearing about them on the radio .... and they're gluten free!  (I have Hashi's).  I ate about 3/4 of the box last night. Woke up this morning with a red itchy face and nasal congestion, headache, anxiety. Hallmark symptoms for me of high MSG intake. (It does say yeast extract on the side but it's pretty far down the list). So if you're sensitive.... stay away! Apparently these particular crackers are loaded with it. 
    • I admit, my blood panel was "mildly positive" with only the DPG IGA being the positive, yet I had a Marsh Stage IIIB (pathologist report) though my visual on the endoscopy was fine.  celiac disease can be hard to diagnose, that is for sure.  
  • Upcoming Events

  • Blog Entries

  • Recent Status Updates

  • Who's Online (See full list)

  • Member Statistics

    • Total Members
      61,688
    • Most Online
      3,093

    Newest Member
    AbuBakar
    Joined