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Gliadin Iga
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9 posts in this topic

I'm still trying to find out what other things can cause a higher than normal IgA?

Since my Endomysial, IgG and Ttg tests were normal, but Celiac runs in the family I have no idea if IgA is anything to base anything on?

My test result on this was a 60, with 30 being normal. My other tests were not even conduted because they were negative and my Ttg was a "1".

Can anyone point me in the direction to get more info on this one test result?

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I would be interested to see what you find out. I am in the same boat.

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Maybe someone out there can help us?????????????

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I am in the same boat except my IgG is high. My doctor says it is inconclusive. I am having an endoscopy on Thursday and have to wait two weeks for the results.

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Just my IgG is high. It is 32. Everything else is fine. Also, I haven't even had any symptoms for the last month. My Dr. said it was inconclusive and wanted me to go gluten-free and see if my symptoms improve, but I really have not had much of a problem (if any) for the past month and I am taking in as much or more gluten than ever. I changed my oatmeal breakfast to Kashi organic waffles (that have lots of fiber, soy protein, and tons of wheat). He wants to hold off on the endoscopy for now. I am thinking about trying the enterolab test.

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I've been gluten-free since Aug. 2003, after a very positive blood test and biopsy. I have always been curious what other conditions can elevate a person's IgA. The next time I'm in the bookstore I'll look at a medical journal and see if I can find some info. on that. The gluten-free diet hasn't been the lifesaver for me I was hoping for, and I've always wondered if this is a similar but not exact disease to celiac disease. If I find out anything I'll let you know, and in the meantime I hope others can shed some light on this!

(I do know a couple things that do this are Tropical Sprue, which is basically Celiac that you catch while travelling to a foriegn country and is treated with antibiotics, and something called Bacterial Overgrowth.)

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My understanding is that the antigliadin tests could be high if you have a wheat allergy (as opposed to celiac disease). The thing is, I'm not sure if you would expect both IgA AND IgG to be high in wheat allergy, or if just one or the other being high is enogh to suggest this. Something to look into a bit farther.

Best,

Kaylee

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I called and asked for a repeat IgA, IgG and Endomysial. The gal at the doctors didnt know what I was talking about, so I hope the doctor calls me instead next time!

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My son's antigliadin IgA and IgG are both elevated. His endoymisial and tTg are in normal range. He also has a casein allergy (IgE response). The doctor advised me to eliminate milk from his diet. Apparently ingesting milk products damages the intestines and allows particles that should normally stay inside the intestines (like wheat) to leak out into his system. His immune system attacks the particles, explaining the elevated gliadin IgA and IgG. Once his intestine heals, the gliadin antibodies should go back to normal. The doctor called this "leaky gut." It's also refered to as intestinal permiability.

I'm not completely convinced, but I'm following the advise to eliminate milk for now. He is still having intestinal symptoms. The doctor has ordered more blood tests to check for IgA deficiency and nutrient deficiencies.

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    • I would suggest you test your daughter through a doctor. The Enterolab tests are not recognized as accurate or reliable by the medical profession. See this link from the Chicago Celiac Disease Center: http://www.cureceliacdisease.org/faq/why-dont-you-recognize-tests-stool-tests-or-otherwise-for-gluten-sensitivity-that-are-currently-available-through-companies-like-enterolab-or-cyrex/
    • Sorry.  Something is wonky with either my connection or celiac.com! Your results are not specific...borderline.    That is why your PCP should refer you to a GI for further celiac blood tests and a possible endoscopy.  I recognize the lab report form.  Kaiser?  If so, a PCP can not order a full celiac panel.  Only a GI can do so.  Why bother?  Because if you test like me, the TTG tests are always negative.  Request the EMA and the DGPS test via a GI.   Do not be fooled by a lack of abdominal symptoms.  I was only anemic -- no abdominal issues at all.  Constipation is a symptom.  Your PCP is thinking is just historical Classic celiac disease symptoms.   Please email your doctor for the referral if you think you might have celiac disease and want a solid answer.    
    • Hello, I have frequent canker sores (roughly comes back every couple of months). Some blood test results are as following. Component Your Value Standard Range TISSUE TRANSGLUTAMINASE IgG 0.31 Index <=0.90 Index Tissue transglutaminase IgA 0.96 Index <=0.90 Index My doctor said that result is unspecific, and I unlikely have celiac disease, since I do not have other abdominal symptoms. For reference, I do have frequent constipation, excessive gas, frequent canker sore, etc. Do you think an upper endoscopy is recommended? I am a little hesitate considering the risk of this procedure and the fact that my symptoms are not that bad. I appreciate all suggestions.  
    • Hello, I see you posted this a long while ago, and perhaps--I hope-- it's no longer a matter of concern, but I thought I'd mention that shortly before I was diagnosed for celiac's, I had distinct yellow blotches on the corners of my eyelids toward my nose. Some months after I had stopped eating gluten, the yellow gradually went away, and--as it just reappeared now several years later, I googled the issue again.  I am only speculating here, but I do believe it is related to liver problems, which, in turn, are related to celiac's. I don't think liver function tests cover all aspects of liver health. I say this because when I was pregnant I developed a temporary liver condition called interhepatic colestasis of pregnancy (ICP), but my liver function tests had been fine. (The condition is diagnosed based on bile levels in the blood, not on liver function). I discovered upon some research that (of course!) ICP  can be associated with celiac's disease.  My hunch is this-- that celiac's presents two problems to the liver: 1) the malabsorption of nutrients--esp. Vit. K2-- that are vital liver health; 2) since gluten registers as a toxin to the immune system (I think?), perhaps the liver gets overloaded processing so much toxic material. Or perhaps there's some other reason. At any rate, poor liver health and celiac's do seem to be linked, according to a few articles I've found. Anyway, hope your problems are resolved now.  
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