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Gliadin Iga
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9 posts in this topic

I'm still trying to find out what other things can cause a higher than normal IgA?

Since my Endomysial, IgG and Ttg tests were normal, but Celiac runs in the family I have no idea if IgA is anything to base anything on?

My test result on this was a 60, with 30 being normal. My other tests were not even conduted because they were negative and my Ttg was a "1".

Can anyone point me in the direction to get more info on this one test result?

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I would be interested to see what you find out. I am in the same boat.

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Maybe someone out there can help us?????????????

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I am in the same boat except my IgG is high. My doctor says it is inconclusive. I am having an endoscopy on Thursday and have to wait two weeks for the results.

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Just my IgG is high. It is 32. Everything else is fine. Also, I haven't even had any symptoms for the last month. My Dr. said it was inconclusive and wanted me to go gluten-free and see if my symptoms improve, but I really have not had much of a problem (if any) for the past month and I am taking in as much or more gluten than ever. I changed my oatmeal breakfast to Kashi organic waffles (that have lots of fiber, soy protein, and tons of wheat). He wants to hold off on the endoscopy for now. I am thinking about trying the enterolab test.

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I've been gluten-free since Aug. 2003, after a very positive blood test and biopsy. I have always been curious what other conditions can elevate a person's IgA. The next time I'm in the bookstore I'll look at a medical journal and see if I can find some info. on that. The gluten-free diet hasn't been the lifesaver for me I was hoping for, and I've always wondered if this is a similar but not exact disease to celiac disease. If I find out anything I'll let you know, and in the meantime I hope others can shed some light on this!

(I do know a couple things that do this are Tropical Sprue, which is basically Celiac that you catch while travelling to a foriegn country and is treated with antibiotics, and something called Bacterial Overgrowth.)

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My understanding is that the antigliadin tests could be high if you have a wheat allergy (as opposed to celiac disease). The thing is, I'm not sure if you would expect both IgA AND IgG to be high in wheat allergy, or if just one or the other being high is enogh to suggest this. Something to look into a bit farther.

Best,

Kaylee

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I called and asked for a repeat IgA, IgG and Endomysial. The gal at the doctors didnt know what I was talking about, so I hope the doctor calls me instead next time!

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My son's antigliadin IgA and IgG are both elevated. His endoymisial and tTg are in normal range. He also has a casein allergy (IgE response). The doctor advised me to eliminate milk from his diet. Apparently ingesting milk products damages the intestines and allows particles that should normally stay inside the intestines (like wheat) to leak out into his system. His immune system attacks the particles, explaining the elevated gliadin IgA and IgG. Once his intestine heals, the gliadin antibodies should go back to normal. The doctor called this "leaky gut." It's also refered to as intestinal permiability.

I'm not completely convinced, but I'm following the advise to eliminate milk for now. He is still having intestinal symptoms. The doctor has ordered more blood tests to check for IgA deficiency and nutrient deficiencies.

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    • Thankyou both! I was wondering if my high levels left much doubt on the diagnosis. I don't see the GI until the 15th Sep and I don't think I can stand to eat gluten in that time. If he tells me to I will do so after then. After 25 years of symptoms I don't think there is much chance of healing my bowel In a couple of weeks. I'm actually terrified of the damage they might find. But I think I will need the endo since there may be other things going on with me. So great they didn't put your son through the biopsy! Once I have a formal diagnosis I have my kids to worry about also. I can't even stand the thought of my daughter having a blood test. I think she would need to be sedated as she is so fearful and pain sensitive. My son is not yet 2 so I don't think they will test him. I'm feeling so off at the moment. I think I have some anxiety and reflux going on complicating things quite a bit.
    • My son's antibodies were 300. Based on his extremely high levels, his pediatric GI suggested genetic testing instead of the biopsy. Genetic testing can't diagnose celiac on its own but combined with such high levels, the gi dr was confident a positive genetic test would confidently diagnose celiac. He warned that biopsies are small snapshots of the intestine and can miss damage. He said this is an approach used very often in Europe but not as much in the US. What sold me on that approach was the ability to put my son directly on a gluten free diet instead of waiting three weeks for the biopsy, during which time he would continue to eat gluten and feel terrible. I'm not sure if this is more common with younger patients though (our son is two), based on the idea that he's had less time to inflict damage that would show in a biopsy? We are very happy that we immediately started the gluten free diet and chose the genetic testing. Our son got the proper diagnosis and his recent number shows a drop to 71 after only 4.5 months gluten free! Not sure if this helps. Good luck and I hope you feel better soon!
    • We have been off gluten for a while now, and symptoms return when I've allowed gluten full meals… so something still isn't sitting right with me.  Checking with her doc about seeing a pediactric GI although I'm not sure how long that will take since we live in small town America. I know she didn't get at least one of the recommended full panel tests but maybe two, can someone help clarify, or is she missing two? DGP for sure and possibly EMA? And if I understand what I'm reading in other posts that the DGP can be more accurate? Thanks Her blood panel results: Ttg ab iga <.5u/ml ttg igg <.8u/ml aga ab iga <.2 u/ml aga an igg <.7u/ml iga 61mg/dL  
    • I was tested for the full panel, I believe. I had normal values for t-transglutaminase (ttg) igg,t-transglutaminase (ttg) iga, deamidated gliadin abs igg, deamidated gliadin abs iga, and immunoglobulin a qn serum.  
    • Going gluten free may be beneficial if you're among the roughly 10 percent of people who suffer from celiac disease, a genetic immune disorder, ... View the full article
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