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      Frequently Asked Questions About Celiac Disease   09/30/2015

      This Celiac.com FAQ on celiac disease will guide you to all of the basic information you will need to know about the disease, its diagnosis, testing methods, a gluten-free diet, etc.   Subscribe to FREE Celiac.com email alerts What are the major symptoms of celiac disease? Celiac Disease Symptoms What testing is available for celiac disease? - list blood tests, endo with biopsy, genetic test and enterolab (not diagnostic) Celiac Disease Screening Interpretation of Celiac Disease Blood Test Results Can I be tested even though I am eating gluten free? How long must gluten be taken for the serological tests to be meaningful? The Gluten-Free Diet 101 - A Beginner's Guide to Going Gluten-Free Is celiac inherited? Should my children be tested? Ten Facts About Celiac Disease Genetic Testing Is there a link between celiac and other autoimmune diseases? Celiac Disease Research: Associated Diseases and Disorders Is there a list of gluten foods to avoid? Unsafe Gluten-Free Food List (Unsafe Ingredients) Is there a list of gluten free foods? Safe Gluten-Free Food List (Safe Ingredients) Gluten-Free Alcoholic Beverages Distilled Spirits (Grain Alcohols) and Vinegar: Are they Gluten-Free? Where does gluten hide? Additional Things to Beware of to Maintain a 100% Gluten-Free Diet Free recipes: Gluten-Free Recipes Where can I buy gluten-free stuff? Support this site by shopping at The Celiac.com Store.

Oral Papain Treatment Gluten Digestion
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2 posts in this topic

Is there any truth to the claims that oral papain can breakdown gluten in the digestive track as claimed in the following link?

http://www.vitasentials.com/digestol.htm

Has anyone tried this and does it work? Any doctors' expert opinion please?

Wayne in Ohio

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Papain is sometimes used culinarily to help break down proteins (hence you may see it in meat tenderizers or papaya in recipes for meat marinades). I don't know if it has any specific action on gluten itself, but they've been looking for this sort of thing for years, and if something as simple as papain worked, I think we'd have heard far more about it out of the research by now.

Another thing that makes me skeptical is the fact that is discusses the enzyme working in the small intestine. That means that the gluten molecule, as a whole, is traveling through your digestive system - which means your immune system is going to react to it. Not to mention the fact that this would be a chemical reaction like any other - needing time, proper conditions, and proper ratios to be effective and carry to completion - something that still gives the immune system plenty of time to react to the gluten molecules before they have the opportunity to be broken down.

(A thing to note here, that I don't think the site you link to fully takes into consideration... Many food intolerances are caused by the lack of an enzyme in the gut. Low or no quantities of lactase cause lactose intolerance. And symptoms from lactose intolerance occur when the sugar goes undigested higher in the gut, and reaches the microbes living throughout the rest of the intestines (where it is consumed, and by products (like gas) are released by the microbes. This is an ENTIRELY different mechanism than gluten intolerance, which is not specifically an enzyme deficiency, but rather an autoimmune condition where a gluten molecule activiates the immune system to attack the body.)

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