Get email alerts Get Celiac.com E-mail Alerts  




Celiac.com Sponsor:
Celiac.com Sponsor:




Ads by Google:






   Get email alerts  Subscribe to FREE Celiac.com email alerts

Thoughts On My Test Results And Symptoms?
0

3 posts in this topic

Hi, I'm looking for advice on what may be the proper interpretation of my test results and symptoms. Three antibody tests were performed on me: Antigliadin IgG was high at 25 units, whereas IgA for antigliadin and tissue transglutaminase were normal at 5 units. From the information I've browsed, it appears as though one interpretation is that in conjunction with the normal IgA tests, the high IgG test isn't diagnostic of proper celiac sprue, though it may instead be indicative other, non-celiac metabolic/immunological abnormalities I may have. On the other hand, I've come across information indicating that in some cases, celiac disease actually results in IgA deficiencies, in which case results like mine are exactly what would be expected. Are these both viable interpretations? Does one sound better than the other?

Additional information about my case: I don't have major, overt gastrointestinal symptoms, though probably an above average amount of GI distress. I have intermittent aching in my arms and legs, fatigue, and "brain fog" symptoms, which appear to result from multiple food/chemical sensitivities. Past experimental attempts I've made at gluten exclusion seem to have resulted in a decrease of abdominal cramping I otherwise have and a change in the character of my bowel movements, though not an overwhelming change in the more bothersome symptoms. Over the past year, I've been dabbling with an unconventional doctor who, with his tests, has found both malabsorption and leaky gut, as well as "detoxification abnormalities." So, one thought I have is that an inherent gluten intolerance may be behind all those symptoms and "alternative" test results, whereas on the other hand, I wonder if I may have other, non-celiac problems causing these symptoms, including perhaps some reactivity to gluten and elevated anti-gliadin IgG, but not proper celiac sprue.

I'll be grateful for any and all thoughts, thanks very much.

0

Share this post


Link to post
Share on other sites


Ads by Google:

Hi Paul,

I'm not sure if I can help you but my IGA was elevated @74 but my

IGG was 16. I read somewhere that having 1 or more of these elevated

antibodies means that you are reacting to Gluten. It may be that you

don't have enough damage to cause both to rise. However, I had no

damage to the villi and a neg biopsy??? My GI doc said he can't prove

I have CS and he can't disprove it so for right now I have Gluten

Sensitivity.

Are you consuming dairy? After I stopped dairy my brain fog lifted

and after 9mos on this diet I am pain free. I think there needs to be

a lot more research on these diseases, I think we are seeing only

the tip of the iceberg. Good luck..

0

Share this post


Link to post
Share on other sites

Paul,

I'm in the same boat as you. My IGG was 40 (positive), my IGA was 23 (I think that's borderline). Through all of my tests, the doctor is looking for something other than celiac, since my tests point mainly to the IGG's. There are other conditions, (intolerance included) that can cause an elevation in only the IGG's as well as I've heard that it can be elevated normally in some individuals. Best thing is to keep talking with your doctor about your symptoms and not give up. Better to error on the side of caution than to find something too late. I've read somewhere that "leaky gut" can result in higher levels of certain things, like IGG's to circulate in your blood. I also have high indirect bilirubin and I'm trying to find out why. Have they ruled out IBD for you?

Like you, if something bizzare shows up in my tests, I want to know why. If you're symptomatic, knowing why is important. Good luck to you.

Gretchen

0

Share this post


Link to post
Share on other sites

Create an account or sign in to comment

You need to be a member in order to leave a comment

Create an account

Sign up for a new account in our community. It's easy!


Register a new account

Sign in

Already have an account? Sign in here.


Sign In Now
0

  • Forum Statistics

    • Total Topics
      104,667
    • Total Posts
      921,670
  • Topics

  • Posts

    • Marip, Have you been diagnosed with celiac disease or Non-celiac Gluten Intolerance?  I notice you joined in 2014.  Did you ever go guten free?  How can we help?   Sorry, I'm not a stool expert!  You could Google it...  Malabsorption?  Standard lab tests that check for anemia and vitamin deficiencies, etc.  should help make that diagnosis.  
    • You can eat just a slice or two (or equivalent) of bread a day for accurate testing.   I understand about the high deductibles.  We're self-employed and we pay for our health insurance. 
    • Sure, if it's gluten free, then fine.  I am very allergic (like anaphylactic) to ibuprofen and aspirin.  So, in my case, I would just tough it out.  Go to bed.  Sleep it off.....eventually. My money is on the garlic and onions.  I can't consume those either (damn that zonulin/leaky gut -- google it along with Dr. Fasano).  I just season with salt, pepper.  Boring.  But no gut issues.  I'm hoping like my lactose intolerance (resolved), that I will get garlic and onions back.   Finally, sometimes just eating anything can hurt when you still have intestinal damage.  Hopefully, you'll feel better in two or three hours if it's celiac related.  Longer if it's an intolerance (leaky gut thing....) Hugs!      
    • I read on their website that all Advil is gluten free, I had such bad pinching cramping today(which I don't why since I prepared all my food at home today.) I made a pot roast, salt garlic, onions...No gluten but still pain, That's the only thing I ate today..I don't eat breakfast or anything.   Anyways.   Is it a good idea to take Advil for the cramping? That's how I would describe it like someone is reaching inside me and pinching me and twisting my insides.    This is what I took  
    • I'll give my PCP a call tomorrow and see what they can offer. My only worry is the expense as anymore tests will put me behind in being able to afford to see the GI. I have high deductible insurance but get money put into my HSA. I'm still trying to pay off the CT scan though. Which is why I'm trying to pick and choose which poses the greatest risk for me right now and what can wait. (Though I would prefer not to wait on any of it.)

      I really do hope its only IBS. Though I always worry IBS is more or less a doctors way of saying "I have no clue" at that point. :C

      Again, I'll be sure to give my PCP a call tomorrow then and see what the options are. I can feel a lot better trying the blood work first. however, once that is done, do I still need to be on a gluten diet before the endoscopy? Also, is it ok if I still mildly reduce the gluten. As in, can I avoid a whole wheat pasta dinner, but still be eating the peanut butter crackers? That sort of thing. Again I guess that is more of a doctor related question. I just wasn't sure if in order to raise your chance, you have to mass consume gluten or not. (Its already in just about everything to begin with.)   --Edit--
      I just now reread the part that you still need to be on the gluten foods even for biopsy so I'll be sure to do that too.
       
  • Upcoming Events

  • Blog Entries

  • Recent Status Updates

  • Who's Online (See full list)

  • Member Statistics

    • Total Members
      61,666
    • Most Online
      3,093

    Newest Member
    epalmer9
    Joined