Get email alerts Get Celiac.com E-mail Alerts  




Celiac.com Sponsor:
Celiac.com Sponsor:




Ads by Google:






   Get email alerts  Subscribe to FREE Celiac.com email alerts

Monosodium Glutamate And Celiac Disease
0

9 posts in this topic

I have been reading some of the old posts about msg and that it is specifically gluten free (unless it is from a wheat source). The research that I have done shows that it is a free form of glutamic acid. I was curious if this extra source of glutamic acid might aid the transglutaminase (tTG) in changing the glutamines at positions p1 and p9 in the HLA-DQ2 and HLA-DQ8 molecules to glutamic acid (due to abundence of glutamic acid or change in pH levels of of the surroundings) causing the T-cell respond to the incorrect sequence in the molecules. Can the presence of the extra glutamic acid trigger a response from the immune system due to sensitivity to the similarity in the change of gluten by tTG?

0

Share this post


Link to post
Share on other sites


Ads by Google:
I have been reading some of the old posts about msg and that it is specifically gluten free (unless it is from a wheat source). The research that I have done shows that it is a free form of glutamic acid. I was curious if this extra source of glutamic acid might aid the transglutaminase (tTG) in changing the glutamines at positions p1 and p9 in the HLA-DQ2 and HLA-DQ8 molecules to glutamic acid (due to abundence of glutamic acid or change in pH levels of of the surroundings) causing the T-cell respond to the incorrect sequence in the molecules. Can the presence of the extra glutamic acid trigger a response from the immune system due to sensitivity to the similarity in the change of gluten by tTG?

Are you proposing that MSG may mimic gluten intolerance, or add to it? I don't profess to understand all the chemistry, but that sounds pretty far-fetched to me, especially any PH effect. I'm guessing that doctors & researchers would have seen that connection right off. But, who knows, you could win a Nobel prize or something! A quick trip to http://en.wikipedia.org/wiki/Monosodium_glutamate reveals several interesting aspects of Glutamate & Glutamine ( I take 4.5g daily as a powdered supplement ). BTW, as far as I know, I personally have never had a problem with MSG, so have never paid much attention to it. Please refer to the link for a listing of naturally occurring glutamate levels in food. This is good info I would recommend to everyone.

"Many people believe that MSG Speeds up the digestion of healthy proteins.

As a result of consuming MSG or protein-based foods, a natural elevation of the blood glutamate level will occur. That level will return to "baseline" (or the level before eating) in about three hours, no matter what the source of glutamate.

Glutamine, and the closely-related compound glutamate, are two amino acids that are critical to human health. In humans, animals, and plants, glutamine and glutamate are transformed into each other as part of numerous physiological processes. The roles of these amino acids in human diseases were intensively researched during the past decade and continue to be the subject of scrutiny. One area of interest is their potential health effects when they are provided in addition to the normal dietary intake that is already several grams per day.

Glutamine has been recommended by nutritionists as a dietary supplement for several serious disease conditions and there is growing research support for this action. Hospital dietitians are aware of the value of administering glutamine in parenteral nutrition (IV nutrition) for critically ill patients, and especially for patients who have had intestinal surgery, but physicians rarely recommend glutamine supplementation in other situations for which it may be indicated. Therefore, it is valuable for other health care providers to be familiar with the over-the-counter availability and uses of glutamine for supplementation purposes."

and of special interest to the MSG sensitive:

"(in the United States) Under current FDA regulations, significant amounts of free glutamate can be included in food under the following ingredient labels: MSG, monosodium glutamate, glutamic acid, hydrolyzed protein, autolyzed protein, textured protein, yeast extract, autolyzed yeast extract, protein isolate, soy sauce, modified food starch, modified corn starch, calcium caseinate, and sodium caseinate. In some cases, significant amounts of free glutamate are also added as broth, maltodextrin, seasonings, or natural flavor."

Theres lots more, also click on the glutamic acid link. best regards, lm

0

Share this post


Link to post
Share on other sites

2/5/07

In response to MSG and glutamates, etc., I need to know if "autolyzed (sic) yeast extract: listed in chicken broth, is potent to someone with celiac disease. I suspect it is used as falvoring, i.e. MSG.

My wife was diagnosed in '98 with celiac disease (blood test only), also lactose intolernace, and has lost about 30 pounds in the last three months (shortly after suspect TIA) but may have now stablized at about 106 lbs, dressed, at 5'4". Trying very hard to maintain strict diet and haven't been able to find out if small intestine has flatened villa and/or there is musous damage to wall, which I suspect is the cause for malabsorption. Will find out in a couple of days. Have her on probiotics, two types (Florastor), enzymes, vitamins, etc. She is very depressed but continues to work as OTR with autistic children. Buy from Whole Foods and bread from Celiac Free local restaruant/bakery that has a celiac disease free menu.

Can't find a local GI speacialist or someone locally that knows what they are doing in this area. I guess I need to find a local celiac disease support group.

Tired of printing up list that are all suspect because of changing contents or discoveries that things are now suspect, or or no longer suspect.

Does any one know how the phase two tests is coming along in Palo Alto, Calif. I am sorry but I don't have the specific info as I am work, but it was the company that got a 21 mil grant to proceed with its specicifc molecule testing.

Sorry for covering to many areas.yeast

I do have a toll free number, but being new to this site, not sure that I can provide it.

Any info is appreciated,

Maximumbob

0

Share this post


Link to post
Share on other sites
2/5/07

In response to MSG and glutamates, etc., I need to know if "autolyzed (sic) yeast extract: listed in chicken broth, is potent to someone with celiac disease. I suspect it is used as falvoring, i.e. MSG.

My wife was diagnosed in '98 with celiac disease (blood test only), also lactose intolernace, and has lost about 30 pounds in the last three months (shortly after suspect TIA) but may have now stablized at about 106 lbs, dressed, at 5'4". Trying very hard to maintain strict diet and haven't been able to find out if small intestine has flatened villa and/or there is musous damage to wall, which I suspect is the cause for malabsorption. Will find out in a couple of days. Have her on probiotics, two types (Florastor), enzymes, vitamins, etc. She is very depressed but continues to work as OTR with autistic children. Buy from Whole Foods and bread from Celiac Free local restaruant/bakery that has a celiac disease free menu.

Can't find a local GI speacialist or someone locally that knows what they are doing in this area. I guess I need to find a local celiac disease support group.

Tired of printing up list that are all suspect because of changing contents or discoveries that things are now suspect, or or no longer suspect.

Does any one know how the phase two tests is coming along in Palo Alto, Calif. I am sorry but I don't have the specific info as I am work, but it was the company that got a 21 mil grant to proceed with its specicifc molecule testing.

Sorry for covering to many areas.yeast

I do have a toll free number, but being new to this site, not sure that I can provide it.

Any info is appreciated,

Maximumbob

I know before I was diagnosed with celiac I was told to avoid all msg for reactions, example: chinese food because I felt so terrible after I ate it, neck pain, light headed heart palps and severe fatigue and of course other minor things but now I wonder if it was the celiac? but otherwise there is a list of symptoms in reaction to forms of msg here is that site............. http://vm.cfsan.fda.gov/~lrd/msg.txt and here is a way to identify hidden types of msg in food labels .......... http://curezone.com/foods/msg.asp and here is last but not least the answer to your question, states here that it is a primary source for msg. I hope this helps http://en.wikipedia.org/wiki/Yeast_extract. and this site but you have to read through it I know its on this page says it may be intolerant for celiacs, I guess be safe than sorry? http://www.e-celiacs.org/2-Gluten-Free%20P...tion%20Diet.htm

0

Share this post


Link to post
Share on other sites

All I know is that I very much react to MSG. It actually gives me symptoms similar to a mild multiple sclerosis flare up. I don't know if I react because it is related to the whole gluten intolerance thing, or if it because of my MS though.

0

Share this post


Link to post
Share on other sites




All I know is that I very much react to MSG. It actually gives me symptoms similar to a mild multiple sclerosis flare up. I don't know if I react because it is related to the whole gluten intolerance thing, or if it because of my MS though.

To all you MSG problematic people:

Beware of Tomato juice or over-ripe tomatoes

0

Share this post


Link to post
Share on other sites
To all you MSG problematic people:

Beware of Tomato juice or over-ripe tomatoes

0

Share this post


Link to post
Share on other sites

I just wanted to add what I'd recently transcribed from a tv health show I watch. I'm very confused about gluten being in MSG - I've read it is and it isn't. Either way, it doesn't sound very healthy. I thought anyone reading about MSG might be able to use this to further their research:

Your Health with Dr. Richard and Cindy Becker (viewed on KSBI-TV Ch. 52, OKC on Tuesday, July 10, 2007)

Today

0

Share this post


Link to post
Share on other sites

Create an account or sign in to comment

You need to be a member in order to leave a comment

Create an account

Sign up for a new account in our community. It's easy!


Register a new account

Sign in

Already have an account? Sign in here.


Sign In Now
0

  • Forum Statistics

    • Total Topics
      104,655
    • Total Posts
      921,622
  • Topics

  • Posts

    • Below is copied & pasted from this thread:   My celiac doctor is Dr. Syed Jafri, in Webster, TX (just south of Houston -- basically the Clear Lake City area), saved my LIFE.  I would recommend him to the whole, entire world.  I was desperately ill, and am still struggling, and he's a wonderful, sweet man who listens and is very proactive in helping you solve whatever problems you're having.  I wish all doctors were like him.  I have to fight and struggle with too many doctors to just listen to me and what I live with, day in and day out.  He's not like that.  Good luck to you.     There are recommendations on this thread too:  
    • I never worried about cross contamination because i was originally told i was just intolerant. after going gluten free i felt so much better up until this last march. dairy and fructose have been giving me problems but both lactose and fructose test came back negative.  this is what my gi doctor emailed me today 
    • Any place you know of to find more info? Seems like I am still in so much pain/bloat, I am not even sure if I would pick the right 5 foods!
    • Don't freak out worrying about other maladies yet. You would be absolutely amazed at the things that can/will resolve on the gluten free diet. Some take longer than others -- neurological seem to take the longest for most people but really, I guarantee, there will be things you had no idea or expectation of resolving will. There were tons for me and then there were things I sort of "woke up one day" & said, "hey, that's gone and that & that & that". Other, larger things had taken my attention so I hadn't paid attention to the smaller things until...... On the other hand, not everything is related to celiac but I bet you wouldn't find a handful of celiacs who didn't say something very similar to what I said above. Yes, thyroid problems are common with celiac but I'll also tell you there are/have been people on here who were hypothyroid before dx but after being gluten-free for a while they actually went back to normal thyroid numbers. My husband is one (yes, we both are celiac - it happens). He was on synthroid for 20 years or more. Guess what? He's not on it anymore. We've had his thyroid panel done several times since about a year gluten-free & he is no longer hypothyroid. 
    • Yes please, that'd be awesome Having a fun time trying to reply on my phone due to broken screen but will be back on tomorrow after results of doctor appointment to get to the bottom of why they've given me seemingly wrong advice re: next steps. Yup I'll admit to pity, anger, frustration and outright fear, been through the mill of emotions in this first week that's for sure. One thing before I go for that; back when I was self-diagnosing I wanted a full thyroid panel (T3, T4 etc.) and also ESR & CRP checks for vasculitis and similar maladies. Now it seems from my reading they can often follow celiac so my worry level of those has gone up a notch, more blood tests ahoy it seems? Main reason for worrying about those is the nearly constant tight / tender head I have at the moment. Top and sides of scalp. Could be the stress tensing the shoulders and occipital muscles at back of head but after the celiac diagnosis being missed I'm fearful of anything else being missed. Did anyone else have this tight head feeling at the start? Feels like the skin is being pulled inwards, sometimes goes down for a few minutes here and there and gets worse when sitting I think. I see the term "brain fog" a lot but luckily don't seem to have too much of that at present, this is more a physical sensation.
  • Upcoming Events

  • Blog Entries

  • Recent Status Updates

  • Who's Online (See full list)

  • Member Statistics

    • Total Members
      61,657
    • Most Online
      3,093

    Newest Member
    pablito
    Joined