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The Dq1 Gene
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I have been reading and thinking about everyone and their enterolab test. I seem to find that most of us that have a dq1 gene have malabsorption when we get tested threw enterolab. Has anyone else noticed this.

So if you have the dq1, what was your malabsorption score.

paula

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My daughter had malabsorption somewhere in the low 300's range. She's double dq1.

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I only carry one and had i think 374 i would have to look it up, but my stepson had no malabsorption but the celiac gene wiht dq1, i just find it odd that dq1 seem to have an high malabsorption compared to others.

what do others think about this.

paula

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Hi! I am a double DQ1 and my score was 1480!

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I have double DQ1, malabsorbtion is 487.

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I don't mean to hijack this thread, but since it's about double DQ1, which I am as well, I hope you don't mind. I had a mildly elevated malabsorption score (346), but in addition to this question of malabsorption, I'm wondering if any of you know of any further characteristics associated with double DQ1. I've heard it's associated with neurological symptoms, but I don't really know what that means. Anyone know anything further about this or any other problems related to these genes? I'm trying to learn as much as I can about the genetics of this, so any input would be helpful.

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I don't mean to hijack this thread, but since it's about double DQ1, which I am as well, I hope you don't mind. I had a mildly elevated malabsorption score (346), but in addition to this question of malabsorption, I'm wondering if any of you know of any further characteristics associated with double DQ1. I've heard it's associated with neurological symptoms, but I don't really know what that means. Anyone know anything further about this or any other problems related to these genes? I'm trying to learn as much as I can about the genetics of this, so any input would be helpful.

I can't answer this question with any level of authority. But, my daughter is a very cranky, uncooperative, DRAMATIC little girl on gluten. I mean hysterics of gargantuan proportions, completely inappropriate for her age. When we started the diet, her true personality came back.

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I don't mean to hijack this thread, but since it's about double DQ1, which I am as well, I hope you don't mind. I had a mildly elevated malabsorption score (346), but in addition to this question of malabsorption, I'm wondering if any of you know of any further characteristics associated with double DQ1. I've heard it's associated with neurological symptoms, but I don't really know what that means. Anyone know anything further about this or any other problems related to these genes? I'm trying to learn as much as I can about the genetics of this, so any input would be helpful.

Here are a couple abstracts. I don't know if the disorders mentioned exhaust the possibilities of neurological reactions to gluten. Probably not. I recall seeing one article, I think it was by the doctor here with the long name that mentioned the prevalence of DQ1 in the population he was examining, not just the typical "celiac genes." I don't recall him mentioning double DQ1, though. I wish I could figure out how I got access to that article for free one time! I should have printed it or bookmarked it.

http://tinyurl.com/2jndwd

http://tinyurl.com/2teclo

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My son is a double DQ1, and he was in the low 300 range. He has been dairy and wheat free for over a year and now we are pulling out gluten.

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It is interesting to read how many dq1 people have malabsorption scores that are high or above the 300 mark. It just makes me wonder if maybe we have some sort of diease that is not proven yet but correlates with celiac. I am having a hard time putting what im thinking into words here. Im still ercovering from being glutened this week. When i can think more clearly i will type it all out. But do oyu all think, or am i just pulling at straws trying to figure this out.

paula

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Single DQ1 gene.....malabsorption score = 912.

Even though Enterolab tests were positive (IgA and tTG) the cause of malabsorption was/is unrelated to gluten. Not to say that gluten didnt contribute...but there were other issues causing the malabsorption in my case.

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