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      Frequently Asked Questions About Celiac Disease   09/30/2015

      This Celiac.com FAQ on celiac disease will guide you to all of the basic information you will need to know about the disease, its diagnosis, testing methods, a gluten-free diet, etc.   Subscribe to FREE Celiac.com email alerts What are the major symptoms of celiac disease? Celiac Disease Symptoms What testing is available for celiac disease? - list blood tests, endo with biopsy, genetic test and enterolab (not diagnostic) Celiac Disease Screening Interpretation of Celiac Disease Blood Test Results Can I be tested even though I am eating gluten free? How long must gluten be taken for the serological tests to be meaningful? The Gluten-Free Diet 101 - A Beginner's Guide to Going Gluten-Free Is celiac inherited? Should my children be tested? Ten Facts About Celiac Disease Genetic Testing Is there a link between celiac and other autoimmune diseases? Celiac Disease Research: Associated Diseases and Disorders Is there a list of gluten foods to avoid? Unsafe Gluten-Free Food List (Unsafe Ingredients) Is there a list of gluten free foods? Safe Gluten-Free Food List (Safe Ingredients) Gluten-Free Alcoholic Beverages Distilled Spirits (Grain Alcohols) and Vinegar: Are they Gluten-Free? Where does gluten hide? Additional Things to Beware of to Maintain a 100% Gluten-Free Diet Free recipes: Gluten-Free Recipes Where can I buy gluten-free stuff? Support this site by shopping at The Celiac.com Store.

Any History Of Duodenal Or Peptic Ulcers?
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10 posts in this topic

Hello Everyone,

I've knowingly been gluten sensitive for the last four years (now age 48), but had bleeding duodenal ulcers twice as a young teen. I'm wondering if anyone else has a similar history and, if so, whether there is a cause-and-effect relationship between these phenomena? Further, which is the cause and which is the effect? In retrospect, I've had isolated, sporadic symptoms of gluten sensitivity throughout my life, but nothing really persistent until relatively recently. Ulcers are now generally attributed to bacterial (helicobacter) infections, but perhaps gluten sensitivity predisposes one to such infections. Comments?

Thanks

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Ads by Google:

during endoscopy GI found duodenal ulcer in husband....it was halfway healed ...

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Ulcers were one of my DD's primary presentations.

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When my dd was 14 months old, she had an endoscopy done and the GI found some ulcers in her stomach. He said they were most likely from gluten, even though her celiac tests were negative. Also, her H. pylori bacteria (the bacteria that can cause ulcers) test was negative. So, yes, I believe that ulcers can be caused by gluten if you are a celiac or gluten intolerant.

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Nope, no ulcers whatsoever!

neesee

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I think I've had gluten problems my entire life, just not known about it until a year ago.

Some years ago I was told I had a duodenal "irritation." This was way before anyone knew about H. pylori. I got the standard advice given to ulcer folks back then, which had no effect on what I felt. I think it was a gall bladder problem; sometimes my food just wouldn't digest and I would experience quite a bit of pain. I just learned to avoid the foods that set me off, mostly high fat items and in particular eggs.

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I think I've had gluten problems my entire life, just not known about it until a year ago.

Some years ago I was told I had a duodenal "irritation." This was way before anyone knew about H. pylori. I got the standard advice given to ulcer folks back then, which had no effect on what I felt. I think it was a gall bladder problem; sometimes my food just wouldn't digest and I would experience quite a bit of pain. I just learned to avoid the foods that set me off, mostly high fat items and in particular eggs.

That is what they told me this past July when I had an endoscopy to look for an ulcer. I had all the classic symptoms, and everyone was convinced I had one, even though the H. pylori test was negative and Nexium didn't help my severe stomach pain and obvious adominal tenderness.

Unfortunately, they didn't look in or biopsy my small intestine, but the pain went away just 3 days after starting the gluten free diet.

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Prior to going gluten-free I was diagnosed over and over with ulcers, always after the endoscope confirmed my doc's diagnosis.... They always said I was too young for all that, but yet I had them. I personally believe that the gluten was keeping my stomach and intestines "roughed up". I know that now that I am gluten-free, 2 years later, I am alot better. I don't take med's for it. Only when really stressed out (ie moving or a death in the family) do I have that kind of pain.

Lollie

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Well, clearly I'm not the only one who has experienced both ulcers and gluten sensitivity. But, the question remains as to whether there is a causal relationship, and which is the chicken and which is the egg if they are in fact intertwined phenomena.

If I had to speculate, I would predict that gluten sensitivity is causal since it can cause upper small intestine erosion of a sort. But, on the other hand, ulcers might be causal since their damage may allow the immune system to begin to recognize and attack the otherwise normally protected tissues, as occurs in celiac. A controlled study may be in order here!

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I've been gluten free for about three years, but I'm sure I've had celiac for about 30 years (I'm 56). I had a peptic ulcer about 20 years ago (negative for h pylori). I'm not sure about cause and effect, but I do know that before going gluten free, my stomach also had some problem (pain, gas, nasea, etc.) I haven't had any of those problems since going on the diet.

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    • Gluten ataxia...?
      I was explaining that some people have other trouble that is immune related and caused by eating gluten, but doesn't effect the gut in a noticeable way. According to the paper that I quoted there are some people which have different types of brain problems but don't have inflammation when tested by a biopsy.  The author used the term "non-Celiac gluten sensitivity" to refer to anyone who has any brain trouble that can be traced to gluten but without obvious gut inflammation.  There are a lot of different possible ways gluten can effect the brain some may not be related to the gut.  It could still be an immune system problem.  Normally "non-Celiac gluten sensitivity" refers to just a food intolerance.  Withdrawal symptoms are not normal and could be indicative of an immune system response of some sort, but I don't know for sure.        
    • Weird Reaction
      Hi Richie I've put the above in quotes as you have described in the first and second sentence how I felt six months prior to my DX.   In my own case, in the end I concluded it was anxiety after consulting Dr Google!  It was such an alien feeling to me, I couldn't even think what it was, particularly as life was pretty good at the time.  Anxiety is a problem for a lot of celiacs prior to diagnosis, and often after glutening after going gluten-free. You mention breathlessness, this of course can be for reasons such as anaemia (again a common celiac problem, I had this prior to DX) but of course also can arise if you are anxious.   Re 'gluten free' - Flowerqueen is right, from what I have read on this forum some people really do seem to react with less than 20ppm.    But perhaps some other things to consider...  could there be something wrong with the batch you have consumed?  Might it be worth contacting the manufacturers?   That said, you could , as Flowerqueen suggests, have a problem with another ingredient, in the product or something else you consumed. In the past I have had a terrible reaction - fever, trembling, diarrhea, stomach cramps that lasted up to three hours the last three times I ate..... broccoli, of all things.    Who would have thought that possible?  I have often thought I should try it again, just to be sure it was the broccoli, as it is a 'super food' that I ought to have in my diet, that I like very much, but the thought of having such a reaction again has put me off. I do hope you will find some answers soon.  
    • Weird Reaction
      Hi Richie,  I've not heard of this drink before, as I live in the UK, but any drink made from barley is something you should avoid.  There's a brand in the UK that makes lemon and barley water and orange and barley water and Coeliac UK say it is not safe for people with Coeliac disease.  (Our labelling laws in the UK changed a couple of years ago).  You say the drink you had was under 20 ppm, which is acceptable (usually) for coeliacs, but a lot of people are super-sensitive to gluten even in very small amounts.  I recently had a similar problem with something which was supposed to be okay for coeliacs, but when I checked the website of the product, for all it said there were no gluten containing ingredients, it was produced in an area where gluten was present, which was enough to put me off and must admit, the symptoms you describe sound very much like I experienced at the time.  (Personally I'd be avoiding that particular drink like the plague from now on). One other thing though,  have you checked the ingredients to see if there could be anything else in it which you may be intolerant to? 
    • Confused
      I have not. I'll talk to my doctor about it
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