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Gluten Blocker Now Being Tested!


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23 replies to this topic

#1 Joni63

 
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Posted 13 February 2008 - 05:32 AM

I found this interesting.

http://abclocal.go.c...=...&id=5950129
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Joni


Dx'd with Celiac Disease 8/01/07

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#2 happygirl

 
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Posted 13 February 2008 - 05:39 AM

Thanks for sharing the link!

AT-1001 has been in various phases of clinical trials for the past few years, and has moved along very quickly, with all positive reports.

Zonulin was identified by Dr. Alessio Fasano, a leading Celiac researcher/pediatric GI at the Univ oF MD-Baltimore (www.celiaccenter.org). More info can be found at: http://www.albatherapeutics.com/
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#3 jerseyangel

 
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Posted 13 February 2008 - 06:38 AM

I saw the report last night. It was very good--it featured Jax Peters Lowell, author of The Gluten Free Bible. She's taking part in the study of the new med.
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Patti


"Life is what happens while you're busy making other plans"

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#4 jkmunchkin

 
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Posted 13 February 2008 - 06:56 AM

Very interesting. Sounds like the study is really moving along well.

Someone might want to let the news anchors know what gluten is though. I think they might have thought it was sugar (glucose); because at the end they said you can always see the gluten content of what you buy in the supermarket listed on the back of the package. Last time I checked that wasn't in the nutrition information. ;)
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Jillian

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Inflamed stomach lining
Gluten free since July 6, 2005
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"Sometimes being a b$tch is all a woman has to hold onto." - Dolores Claiborne

#5 RiceGuy

 
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Posted 13 February 2008 - 08:21 AM

Something tells me there are side effects, but they just don't know yet. Just like a Celiac can go undiagnosed for years, so can a side effect. Also, it doesn't mean one can eat gluten on any regular basis. I get the impression it's mainly for CC, like you might get from eating out.

I won't be taking it. I also think it's just a "bandaid", and the real problem is that wheat is no longer what nature intended.
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#6 Joni63

 
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Posted 13 February 2008 - 10:53 AM

I saw the report last night. It was very good--it featured Jax Peters Lowell, author of The Gluten Free Bible. She's taking part in the study of the new med.


I know! I thought it was facinating that she was taking part in the study. Should be interesting to see the results in the end.

Something tells me there are side effects, but they just don't know yet. Just like a Celiac can go undiagnosed for years, so can a side effect. Also, it doesn't mean one can eat gluten on any regular basis. I get the impression it's mainly for CC, like you might get from eating out.

I won't be taking it. I also think it's just a "bandaid", and the real problem is that wheat is no longer what nature intended.


I just said this to my husband this morning. I was wondering how many people will think they can eat gluten daily and just take these pills to counteract it.

I also think it is a bandaid of sorts. I can't say that I won't every try it though. I think it would be nice to have something to carry with me in case I ever run into a situation where I have to eat some place where I can't get gaurenteed gluten free food. It might also be nice for those who travel a lot in their jobs.
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Joni


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#7 dbmamaz

 
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Posted 13 February 2008 - 11:05 AM

I'm thinking about all the people who know they're celiac but arent willing to do the diet - might help them, some at least. The bigger problem is that doctors (who so often say, oh, you dont want to go on that diet, its too hard or too expensive) will prescribe a pill and never give any information about the diet. On the other hand, with a drug to sell, the testing for celiac should become more common!
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A.L.C.A.T. test showed over 50 sensitive foods
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Regular allergy testing reacted to every inhalant and all but 6 foods.
Slowly adding in foods, started w 19 and now have 25

#8 kbtoyssni

 
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Posted 13 February 2008 - 11:41 AM

My first response was that maybe this will increase awareness and diagnosis if drug manufacturers are promoting the disease. BUT - I worry that the diagnosis will be taken lightly. I think of the few people I know with lactose intolerance and they take lactase most of the time, but not all of the time. I also don't want this to affect my ability to get truly gluten-free food. It's certainly my biggest personal worry - will restaurants stop taking me seriously if they think I can just take a pill?
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#9 kbtoyssni

 
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Posted 13 February 2008 - 11:42 AM

DELETED - double post.
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Gluten-Free since September 15, 2005.
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#10 tom

 
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Posted 13 February 2008 - 01:11 PM

Ugh they call it "Gluten Blocker"?!

What it really treats is leaky-gut. I'd have to read a LOT more to be convinced there's no damage from celiac w/out the intestinal permeability issue.

In fact, I'm wondering now if they assert that the villi problems can't occur w/out leaky-gut. Hmmmmm

So far, I can only agree that the celiac issues in OTHER parts of the body, i.e. neurological for one, won't happen w/out leaky-gut allowing the baddies into the bloodstream. (This isn't an endorsement of AT1001's ability to accomplish this & I don't even know about the ability to even measure the effectiveness)
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>>>>>>> tom <<<<<<<

Celiac 1st diagnosed as a toddler, in the 60s. Docs then, between bloodletting & leech-tending, said "he'll grow out of it" & I was back on gluten & mostly fine for 30yrs.

Gluten-free since 12-03
Dairy-free since 10-04
Soy-free since 5-07

#11 jerseyangel

 
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Posted 13 February 2008 - 01:26 PM

What it really treats is leaky-gut.

This is my thinking too. They said in the report that they are testing it on Celiacs, but it may of use with other autoimmune diseases.

What I wonder is, will this pill have any effect on other food protein intolerances? While I wouldn't use it so I could eat gluten (shudder), I might give it a try so I could have a more varied diet since I have several other sensitivites.
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Patti


"Life is what happens while you're busy making other plans"

"When people show you who they are, believe them"--Maya Angelou

"Bloom where you are planted"--Bev

#12 Joni63

 
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Posted 13 February 2008 - 06:28 PM

What I wonder is, will this pill have any effect on other food protein intolerances? While I wouldn't use it so I could eat gluten (shudder), I might give it a try so I could have a more varied diet since I have several other sensitivites.


I wouldn't use it to eat gluten either. Now that I'm away from it and I know it's bad for me, eating it on purpose just doesn't seem like an option. My thinking is that it would provide a measure of safety where cross contamination could possibly be an issue.

It would be great if it could help with leaky gut issues too.
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Joni


Dx'd with Celiac Disease 8/01/07

#13 Lawrence

 
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Posted 13 February 2008 - 09:09 PM

Here is a list of places within ten miles of where I live that you can buy the new pill: http://www.nowfoods....submit=Find NOW In the Mrs. Green's add it says it is not FDA approved yet but I would give it a try. I'm kind of surprised most people are so reluctant to even try it. I would not go off the diet 100% but I would at least have one day a week where I would take the pill and enjoy some regular food. I got to admit I really miss real Italian and Chinese food. The Italian substitutes aren't that bad but there is nothing like the real thing. I also guess it depends on the person though. I never had any of the symptoms of Celiac, only when I had accidental gluten after being on the diet was I affected and that was mostly through alcohol. I think the best thing is for each person to talk it over with there doctor and see where their gluten levels are before they start the pill and where they are and how they feel one month later. It will work for some and probably fail for some others. I think this is a good break through.
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#14 tom

 
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Posted 13 February 2008 - 10:46 PM

Here is a list of places within ten miles of where I live that you can buy the new pill:

Not sure what pill you're talking about, but this thread is about AT-1001, which is still in clinical trials and hence NOT available commercially.
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>>>>>>> tom <<<<<<<

Celiac 1st diagnosed as a toddler, in the 60s. Docs then, between bloodletting & leech-tending, said "he'll grow out of it" & I was back on gluten & mostly fine for 30yrs.

Gluten-free since 12-03
Dairy-free since 10-04
Soy-free since 5-07

#15 RiceGuy

 
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Posted 14 February 2008 - 05:06 AM

My first response was that maybe this will increase awareness and diagnosis if drug manufacturers are promoting the disease. BUT - I worry that the diagnosis will be taken lightly. I think of the few people I know with lactose intolerance and they take lactase most of the time, but not all of the time. I also don't want this to affect my ability to get truly gluten-free food. It's certainly my biggest personal worry - will restaurants stop taking me seriously if they think I can just take a pill?

Yeah, now that might be a real concern. Let's face it, the entire medical industry is an "after the fact" sort of thing. They are reactive, not proactive. In other words, people seem to seek medical attention or take care of themselves only after something goes wrong.

This is my thinking too. They said in the report that they are testing it on Celiacs, but it may of use with other autoimmune diseases.

What I wonder is, will this pill have any effect on other food protein intolerances?

Now that's a really good point. I mean, if it can help other conditions, then it must block other molecules, right? So that tells me there will be more malabsorption due to certain things being blocked. Maybe the initial reaction from gluten doesn't occur, but then you'll have to wait till the drug wears off, then swallow heaps of supplements to make up for the loss of all the nutrients. Great, so it turns good food into junk food. Yet another medical marvel.

I hope that's not what's happening, but something tells me it is, or at the very least it will turn out to do more harm than good. But chances are we just won't know about it until people start dying.
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A spherical meteorite 10 km in diameter traveling at 20 km/s has the kinetic energy equal to the calories in 550,000,000,000,000,000 Twinkies.




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