Get email alerts Get Celiac.com E-mail Alerts  




Celiac.com Sponsor:
Celiac.com Sponsor:




Ads by Google:






   Get email alerts  Subscribe to FREE Celiac.com email alerts

Dapsone
0

8 posts in this topic

I have been on Dapsone for my DH for a while, and I finally had weaned myself off of it about a month ago... however I ate something, I don't know what, and broke out, and i started taking it again. However, I also noticed a couple things that have been really bothering me in association with Dapsone. For the longest time while taking Dapsone, I had no problems... then I had the liver problems and had to go off of it. However, after my liver straightened up and I started taking it again, I (along with my girlfriend) noticed that I get really moody when I'm on Dapsone. Is there a proven correlation or has anyone else experienced this? Again, it didn't do this until after I went off it for about a month (I was itching like crazy though). When I started taking it again, it was like I was always depressed, and when I finally weaned myself off it, I felt like a different person. I was never angry or depressed or anything like I had been. However I started taking it about a week ago again, and I feel horrible right now, like really depressed for no reason and feeling kinda worthless and I get irritated and angry very easily too... like I have a short fuse. I never used to be like this until a couple months ago and I wasn't merely a week ago when i wasn't on Dapsone. It's bothering me really bad because i even KNOW that I shouldn't be feeling like this, I just do. It bothers my girlfriend for obvious reasons too. I am trying to quit taking it again because I honestly believe that it makes me feel better emotionally. But I do wanna know if anyone knows if that is a possible side effect, or if I am just using the medicine as a copout. Thanks---

0

Share this post


Link to post
Share on other sites


Ads by Google:

I've never heard of this as a side effect but you vcan do a google search and find them or ask your pharmacist for a list if side effects.

richard

0

Share this post


Link to post
Share on other sites

Weird you mention that, I seem to have been having a similar problem.

Out of interest how did you know you had liver problems, from tests or did you become ill?

0

Share this post


Link to post
Share on other sites

If you're taking dapsone, your doctor should be doing regular blood tests and liver panel. I never had a liver problem but my white cell count was way off at first.

If you haven't gone gluten-free you need to.

richard

0

Share this post


Link to post
Share on other sites

I think a lot depends on how much you arev taking.

Some people when they start take like 200MG a day. Currently, I take 25mg (1 pill) every day or every other day). If I stop taking dapsone, the DH will come back - it always does -- and yes, I have new pots and pans, gluten-free toiletries and I rarely eat out -- for some reason, it doesn;t go away.

Anyway, I have been on it for 8 years (albeit a low dose) and my CBC has always returned normal.

For what its worth, when I used to drink and take 50 mg of Dapsone, I had moody issues -- but I always viewed it as stress, being hungover (colllege days) and working in a restaurant..

Who knows?

BTW< what is your dosage?

0

Share this post


Link to post
Share on other sites




I normally take 50mg a day. Sometimes less sometimes more but an average of 50mg. I have not had any blood tests at all and have been taking it for about 5 months. I have considered getting blood tests but never got round to it as I work up to 70 hours some weeks. I should really get some tests.

I am gluten free but still seem to get some itching once in a while even when I have only eaten food items that I know to be gluten free. I honestly think half of it could be in my head and dapsone these days is a placebo. As they say the mind is a very powerful thing.

Interesting you mentioned the alcohol and mood problems. I went out drinking last night and I have been feeling moody/depressed all day. Could be down to the fact my skin is itching due to my yeast allergy. Drives me f**king mental all the food allergies I have, I just wish I could eat and do what I want just like 99% of other people out there.

0

Share this post


Link to post
Share on other sites
I normally take 50mg a day.  Sometimes less sometimes more but an average of 50mg.  I have not had any blood tests at all and have been taking it for about 5 months.  I have considered getting blood tests but never got round to it as I work up to 70 hours some weeks.  I should really get some tests.

I am gluten free but still seem to get some itching once in a while even when I have only eaten food items that I know to be gluten free.  I honestly think half of it could be in my head and dapsone these days is a placebo.  As they say the mind is a very powerful thing.

Interesting you mentioned the alcohol and mood problems.  I went out drinking last night and I have been feeling moody/depressed all day.  Could be down to the fact my skin is itching due to my yeast allergy.  Drives me f**king mental all the food allergies I have, I just wish I could eat and do what I want just like 99% of other people out there.

<{POST_SNAPBACK}>

0

Share this post


Link to post
Share on other sites

<{POST_SNAPBACK}>

Dude, working 70 hours a week and dealing with a hangover is depressing all in itself - never mind the whole gluten-free thing. I try my best to maintain the diet, gave up on boozing and take about 25mgs of dapsone a day. Been doing this for over 5 years, my skin stays clear and I would never characterize myself as depressed - a little grumpy here and there, but nobody's perfect...

0

Share this post


Link to post
Share on other sites

Create an account or sign in to comment

You need to be a member in order to leave a comment

Create an account

Sign up for a new account in our community. It's easy!


Register a new account

Sign in

Already have an account? Sign in here.


Sign In Now
0

  • Forum Statistics

    • Total Topics
      104,679
    • Total Posts
      921,707
  • Topics

  • Posts

    • egs1707. Are you in Canada?  It's NOT a good idea to go gluten free between now & the GI appt. and here's why.... MOST of us have MUCH stronger reactions to gluten when we go back on it for the endoscopy. A lot of people have had such strong reactions that they have been entirely unable to complete the challenge and have to call it quits. This means they never get an official dx. It's your call, you make the choice. However, I will say that you don't have to eat a lot of gluten, a couple saltines or a slice of bread per day. 
    • You mentioned the tight head. Yes, both my celiac sibling and I had head pressure. Mine was horrible last glutening with eye pain as well. Like someone put a vice around my temples. I swore it felt like a parasite infected my gut, thyroid and brain. It is going away mostly, still have it on and off a bit.  My brother said his naturopath informed him some celiacs get a bit of inflammation in the brain.   
    • Hi All this is my blood test result 1.immunogloblulin serum 203 ( 87-350) 2.Deamidated Gliadin IGA  4 ( 0-19 negative) 3.Deamidated Gliadin IGG 3(0-19 negative) 4.Transglutainase IGA <2 ( 0-3 negative) 5.Transglutainase IGG <2 ( 0-3 negative) does it mean most likely no celiac ? thanks.  
    • At the moment it's microwave rice packets as it needs to be something easy for lunch at work. What do you choose for breakfast? At the moment I have gluten-free porridge oats with fruits but also seeing oats are a bit of a gamble in the early days. Trying to figure out how long a reaction takes to show up i.e. if I feel ropey later in the day is it really lunch as I'm blaming at present or actually is it something from the morning or even night before? The food is the toughest bit for me right now; wasn't that great with it before so will need plenty ideas from you good people... seems I'm in the right place though   
    • I know what you're going through - it's that grieving process and it's tough.  I was diagnosed in 2013, and aside from an occasional pity party, I don't look back. I have my restaurants where I feel safe, I have the food I know I can eat, and I get on with my life.  I'm lucky that I live in a big city with lots of options, but you can make this work, and you will feel better and once you do, you'll stop grieving.  The people on this site helped enormously. It is tough in the beginning to know if you've been 'glutened' vs. just going through withdrawal.  For that reason alone, it's best to avoid restaurants for a little while and be careful at home - just to be sure what's happening.  Eventually you'll be able to get back to your version of 'normal'.  Oh, I also have hypothyroid/hashimoto's.  No big deal, I take synthroid. Quinoa, eggs, nuts and beans for protein.  You don't have to go crazy on the cooking.  Just eat a lot of whole foods.  There are a lot of complicated recipes out there, but now may not be the time.  Rice noodles in veggie bouillon - easy and cheap.  gluten-free pasta with olive oil, parmesan and garlic - easy.  I eat a lot of rice and have never had a problem - you're not getting it out of one of those bulk bins, are you?  That could be contaminated.  Go with packaged.  Do you have access to the Macro Vegetarian brand of prepared rice dishes (in the refrigerated section).  They have several that are gluten free, they're delicious heated and with a little gluten-free soy sauce.  They're my go to on days I don't want to cook. Good luck!  
  • Upcoming Events

  • Blog Entries

  • Recent Status Updates

  • Who's Online (See full list)

  • Member Statistics

    • Total Members
      61,677
    • Most Online
      3,093

    Newest Member
    Jessica123
    Joined