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Test Result Question
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Hi. My children were recently tested for celiac disease. My 8 year old daughter is an uncontrolled type one diabetic. My 12 year old son shows many classis symptoms of the diesase. When we got the blood test results I was told that my daughter had a positive antiglandin Abs, IgG and my son had a moderate to high positive or the antibody. Both children had negative IgA and tTG tests though. Our doctor said she will wait another 6 months and test again. At that point if they still show positive testing she will refer them to a specialist. My question is whether it is safe to wait and what the 6 month wait would be for. She does not want us to change their diets at all in that time frame. Are there other conditions that could make the IgG positive, but the other antibody tests negative? My doctor seemedvery unsure about all of this. If you have any thoughts on this, Thanks for your input!!!!

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The same thing happened to all three of my children in regards to the testing. They all tested positive on the IgG gliadin antibody tests and not the other tests that are more specific to Celiac. Fortunately they were being seen by a Physicians Assistant who didn't know much about the testing, so when he called to give me the test results he asked if I wanted referrals and I said YES! So now they are all being seen by a wonderful Pediatric GI who insisted on repeating the tests with Prometheus labs and running the gene test. And Prometheus routinely checks for IgA deficiency with their Celiac Panel, since the frequency of IgA deficiency is higher in Celiacs.

The reason your doctor is wanting to wait is to see if they will start producing IgA mediated antibodies in the next six months. This is not necessary and certainly unreasonable, since some people never produce antibodies in the blood high enough to register as Celiac. I am one of those people. I had myself tested through Enterolab , and that showed that I had the main gene responsible for celiac disease, and that I was producing positive levels of antibodies in my intestines, but they had not yet moved out into my blood stream. I also had minimal damage in my intestine, despite the fact that I have been sick since I was 4 years old. (I'm now 31) So I don't see how it would hurt for your doctor to send your kids to a specialist. Are you a Celiac? Does it run in the family? If there is a family history, then they should at least have gene testing. It is recommended that if you test positive on the gene, that you maintain a gluten free diet, so you don't aquire celiac disease in the future.

I wish you luck, and God bless,

Mariann :)

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