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Help With Cd Link To Schizophrenia


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16 replies to this topic

#1 PsyDbound

 
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Posted 11 February 2005 - 01:12 PM

I am currently doing reserch on gut permibility and shizophrenia.I don't quite understand the celular process after penetration of the mucosa. I would appriciate any help in getting a clear picture of the transition from anti-gliden to abnormality of the t-cell and the brain connection. Please keep in mind that I am Psych trained and not medical.

Thanks for you time,
Christina
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#2 MySuicidalTurtle

 
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Posted 11 February 2005 - 01:18 PM

I hate to seem daft, but I think you would get more help by explaining what you need in other words.
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#3 PsyDbound

 
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Posted 11 February 2005 - 01:30 PM

Sorry, my bad. Im just having a hard time with the physiology of celiac disease after it has damaged the villi. I know that malabsorbtion is a problem but I don't understand what is being tranfered past the gut wall to the t-cells and what they have to do with schizophrenia. I am sorry if this isn't clear but I really dont understand it myself. Also, if I have misunderstood the whole villi breaking part please correct me.

Thanks,
Christina
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#4 Carriefaith

 
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Posted 12 February 2005 - 09:12 AM

I have read in the book Wheat Free Worry free: The Art of Happy, Healthy Gluten-Free Living by Danna Korn that celiac and schizophrenia may be related. I believe that there is a section in the book on this topic.
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Carrie Faith

Diagnosed with Celiac Disease in March 2004
Postitive tTg Blood Test, December 2003
Positive Biopsy, March 3, 2004

#5 MySuicidalTurtle

 
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Posted 12 February 2005 - 09:57 AM

I never thought about the two being connected but I can see how they could be, along with other disorders. Very interesting stuff.
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#6 FaithInScienceToo

 
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Posted 12 February 2005 - 10:06 AM

Quick reply...

Here is a link for a the discussion of this topic - There are numerous references contained in it - perhaps there is something there for you?

http://www.gluten-fr...oggan/schiz.txt

Good luck,
Gina
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"Get busy living
or get busy dying."


From: The Shawshank Redemption
--------------------------------------------------------------
gluten-free since Jan 1 '05
Positive response to diet within days, felt 'alive again' within 2 weeks

Feb 22 '05:
Diagnosed "Celiac Sprue, and IBS" by a GI doc, Dr. David Lin of Danville, CA
via blood testing 53 days after I began the gluten-free diet on my own:
Test results at 53 days POST going gluten-free were:

Gliadin AB IgA = 29.9
Since 30+ = positive for Celiac Disease when ingesting gluten, my doc
diagnosed me with Celiac Sprue then and there.

Gliadin AB IgG was 5.6 at that point
-------------------------------------------
Endoscopy with biopsies, AND colonoscopy with biopsies were done,
only to rule out other possible GI problems (especially intestinal
lymphoma) - My doctor told me the results indicated "no current damage
found" - and that as long as I stay gluten-free, I don't need another
biopsy for ten years.

Follow-up blood testing was done about one year later, by the same
Gastro doc, in Nov '05:
Gliadin AB IgA =26, Gliadin AB IgG <1

Blood testing done again by him, 5 months later (March '06)
He then told me my tests results were back to normal, and "Keep up the
good work! You can't argue with success!" :-)

I now see him one time per year for routine testing to make sure I am
staying gluten-free.
------------------------------------------------------------------------------------------
ADDTIONALLY:
I was also diagnosed as positive for antibodies and autoimmune
response to gliadin by Enterolab, via stool specimen taken 56 days
gluten-free

and I have one of the two genes that 'cause' Celiac Disease:

"HLA-DQ8," via Enterolabs cheek cell test kit
---------------------------------------------------------------------
I began a COMPLETE 'Gluten-free Casein-free' diet in Nov '05, due to:
"positive" for casein antibodies from Enterolab (in Feb '05)
and
"positive" for casein IgG (Elisa) via York Labs' finger-prick blood
test, Sept '05
and continued 'stomach pains,' although nothing compared to before
going gluten-free....

UPDATE: ALL remaining symptoms disappeared within weeks of going gluten-free&CF!
**********************

My PAST illnesses I believe are attributable to Untreated Celiac Disease:

Recurrent ear and throat infections in childhood
Frequent childhood stomach aches, underweight, picky eater
Tooth enamel problems/excessive cavities in childhood
Diagnosed in 20's with non-allergic rhinitis
Two spontaneous abortions (childless)
IBS diagnosis at age 28 (all better post going gluten-free and casein-free)
["Horrible" digestive problems from ages 32-47 - excess gas,
diarrhea gone post gluten-free!]
Reflux diagnosis at age 35 ('reflux' gone post gluten-free)
ADHD diagnosis at age 38 and at age 48 (not as bad with Gluten-free Casein-free diet)
Broke elbow in 2 places, age 39
Osteopenia diagnosed at age 44 (bone scan revealed thinning of spine -
taking Calcium and Vit D now)
Fibromyalgia diagnosis at age 40 (fatigue and pain all gone post gluten-free!)
Minor depression with anxiety diagnosed at age 42 (taking Paxil)
Skin cancer - squamous at age 43 and pre-melanoma at age 45
Adult acne (this, too, went away, but only after going dairy-free)
Topical dermatitis (so bad I needed steroid shots) diagnosed at age 46
(That's gone now, too!)
Excessive bruising of skin began at age 45:
I was told by derm doc AND family physician "That's just thin, aging
skin, nothing you can do about that" (GUESS WHAT?! ...NO unusual
bruising POST going gluten-free! I can now wear skirts and shorts
again!)


SO many years of being sick...
Hopefully, others will benefit from Science, and the increasing media
attention being given to Celiac Disease and gluten-based illnesses,
and will not have to go through what I, and others on here, have had
to go through.

#7 PsyDbound

 
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Posted 12 February 2005 - 11:52 AM

Thanks for the info, its great and coincides with what I have been researching. I think I may need to confer with a physiologist because I still don't understand what happens on a cellular level. Is seems quite confusing.

Thanks again,
Christina
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#8 Maggie1956

 
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Posted 16 February 2005 - 07:29 PM

Hmmmm, very interesting. <_< My sister is a schizophrenic, and she also has trouble in her gut. She recently tested negative to celiac, but I still think she may be gluten intolerant. I'm not sure how accurate the test was either.

Give us an update when you find out more.
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SUNSHINE COAST, QUEENSLAND, AUSTRALIA

Maggie

Working towards wellness.
gluten-free (or trying to be) since December 1st 2004

positive blood test - Oct. 2004
positive biopsy -Nov. 2004

#9 mommida

 
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Posted 16 February 2005 - 09:51 PM

Have you looked into the studies that show calcifications of the brain in Celiac patients?
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Michigan

#10 Guest_BellyTimber_*

 
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Posted 02 March 2005 - 05:00 PM

As a parallel to this may I suggest Paul Shattock, Paul Whiteley and Dawn Savery who have published the following titles about their work at the Autism Research Unit, School of Health Sciences, University of Sunderland, Sunderland, SR2 7EE, U.K.:

- Autism as a metabolic disorder: guidelines for gluten and casein free dietary intervention

- Autism as a metabolic disorder

- Guidelines for the implementation of a gluten and/or casein free diet with people with autism or associated spectrum disorders

I would be surprised if you didn't find the biochemistry mentioned in these of some interest.

Let us know how you get on - we'll try to follow your terminology!

Michael
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#11 Ruth UK

 
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Posted 03 March 2005 - 01:10 AM

Michael,

I am honestly NOT stalking you. It's just that it's great to have someone from the UK here who is obviously very well read! May I be cheeky enough to enquire what your profession is? (Obviously, don't reply to this if you don't wish to.)

I may have already mentioned this in another post to you, but my lad has ADHD, Asperger's Syndrome and dyspraxia, and in connection with this I would agree with you that the work taking place at the ARU is VERY interesting. My son tested +ve on their tests for 'gluten and casein insensitivity'.

No doubt will speak to you again:)
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#12 LUAP

 
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Posted 03 March 2005 - 11:07 AM

THE ANSWER FOR THE GUT PERMEABILITY IS GIVEN BY DOUG KAUFMANN IN THE FUNGUS LINK.

I HAVE'NT READ ANYWHERE THAT THERE WAS ABNORMALITY WITH T CELLS...T CELLS ARE PRESENT WHEN SOMETHING DANGEROUS IS PRESENT...

LET TALK ABOUT GLIADIN (MEMBER OF THE GLUTEN GROUP).

THE PEPTID THEORY SAYS THAT THE PROBLEM WITH GLUTEN IS THE SIZE OF THE PROTEIN. THE VERY LONG AMINO ACID CHAIN. RESEARCH ARE CONDUCT ON ENZYMES THAT COULD HELP BREAK THAT HEAVY AMINO ACID CHAIN.

THE PROBLEM WITH THE LONG CHAIN...THE LONGEST IT IS, THE MORE THERE IS GLUTAMIC ACID.

GLUTAMINE, MSG, GLUTAMIC ACID...NATURALY PRESENT IN FOOD. GRAINS CONTAINS ALOT OF IT, ALONG WITH TOMATOES, BEETS, AND OTHERS.

REFERS TO THE BOOK: EXCITOTOXINS, THE TASTE THAT KILLS.

IN THOSES 2 BOOKS, YOU HAVE ALL THE ANSWER YOU NEED...IN MY OPINION.

PAUL
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Canada
Where the health cares are free, but where the doctors worry more about their bank account than the health of their patients.
gluten-free since april 2003
On the no grain diet (Mercola) and initial phase diet (kaufmann) since january 2005. healthy since january 2005

#13 PsyDbound

 
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Posted 03 March 2005 - 12:46 PM

Thank you so much for all of your help and support. I am now completing my research and will post a link to my findings. Again, you have all been so helpful.
FYI I have a Mom, 3 sisters and a brother all with celiac disease (thats out of 12 kids and not all have been tested yet). After writing this research I am convinced testing for celiac disease should be universially accepted and preformed before age five.

Thanks,
Christina
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#14 PsyDbound

 
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Posted 10 March 2005 - 07:31 PM

I finished my research and would be happy to e-mail my findings and refrences. Below is a link to a very significant study by William Eaton for the British Medical Journal.

Thanks again for all the great ideas!

Christina


celiac disease and Schizophrenia
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#15 Guest_BellyTimber_*

 
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Posted 14 March 2005 - 04:28 PM

Ruth

Didn't think you were.

Not working in any related field.

Over the decades my body has talked to me bit by bit about neurology and metabolism leading me to other sources of information. The spirit leading through the body. Making better sense of my life history (so far).

I get little pieces or batches of thoughts together & can express them all in one but the general skill of information organising comes very difficult to me, a kind of dyslexia I think. My having hyperfocussed on words since an early age and excellent spelling and handwriting masked that to "experts"!

Despite so much of my life being behind me fortunately I still have my life ahead of me in some tantalisingly unknown ways...

Michael

:P
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