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Celiac Disease Panel Results


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#1 imnotdyingnow

 
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Posted 23 October 2008 - 06:58 AM

I received my celiac disease panel results. This was a blood test that my doctor told me was positive. Basically I want to understand what it says because it actually looks negative to me.
I am just going to type what it says and hopefully someone can tell me what it means. The doctor will not explain and finally i had the lab fax this to me.


*************************************************************************************************
CELIAC DISEASE PANEL

TISSUE TRANSGLUT AB IGA <3 U/mL

NEGATIVE: <5 CN
EQUIVOCAL: 5-8
POSITIVE: >8

Tissue Transglutaminase (TTG) - IgA positivity offer both high specificity and sensitivity for Celiac Disease.

For patients with early Celiac Disease with subtle histopathologic change (Marsch grade I-II), Gliadin IgA is a sensitive marker.

For patients who are IgA deficient, additional serologic testing would be helpful. TTG-IgG and HLA testing may help establish a diagnosis.
IGA, SERUM 199 mg/dL 81-463 CN
GLIADIN AB (IGA0 13 H U/mL

NEGATIVE: <11 CN
EQUIVOCAL: 11-17
POSITIVE: >17

CN- TESTS PERFORMED AT QUEST DIAGNOSTICS NICHOLS INSTITUTE 33608


VALUES OUTSIDE REFERENCE RANGES
GLIADIN AB (IGA) 13 H U/mL

*************************************************************************************************

Any help would be greatly appreciated. I am on the gluten free diet. I don't feel that much better. I have sensitivity, or i should say, INTOLERANCE, to the following things that I know of:
Corn (bed ridden sick), Dairy(toilet bound), Chocolate(headaches), Red wine (headaches)
I never noticed a problem with gluten but i was depressed, always have headaches, body and joint pain, losing weight, severe irritibility, losing some hair, GI issues sometimes, but MAJOR constipation :o . Sometimes it had been 2 weeks before having a movement - which freaked me out and prompted me to go.
I really dont feel better gluten free. I wonder if it might be something else. The constipation is better and my hair is growing back on the gluten free diet but i still don't feel better in the headache and body ache area.
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#2 lizard00

 
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Posted 23 October 2008 - 07:11 AM

Hi. Welcome :)

Were you gluten free at the time? If you have already been gluten-free at time of testing, then your results should be gluten-free if you have Celiac.
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Be yourself, everyone else is taken.
Oscar Wilde

Gluten free November 2007
IgA Deficient, Neg Bloodwork, Double DQ2 Positive
Dietary and Genetic Diagnosis June 2, 2008
Soy free Jan 09

#3 imnotdyingnow

 
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Posted 23 October 2008 - 09:08 AM

Hi. Welcome :)

Were you gluten free at the time? If you have already been gluten-free at time of testing, then your results should be gluten-free if you have Celiac.



Thanks for replying. I was not on the gluten free diet at the time of testing so my results should not reflect less gluten. Were you able to know what that number 3 on the test meant?
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#4 happygirl

 
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Posted 23 October 2008 - 09:18 AM

According to your results,

tTG IgA: normal
Total IgA (not a Celiac tests, but measures antibody production): normal - you are not IgA deficient
AGA IgA: Slightly elevated/equivocal
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#5 imnotdyingnow

 
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Posted 23 October 2008 - 11:12 AM

According to your results,

tTG IgA: normal
Total IgA (not a Celiac tests, but measures antibody production): normal - you are not IgA deficient
AGA IgA: Slightly elevated/equivocal


Thank you so much for that reply. So, if i have slightly elevated IgA...should i worry about doing a gluten free diet? Does this mean that I have a gluten intolerance?
My doctor told me, according to this test, that it was positive for celiac although the levels were low.

This diet is so restrictive and expensive. I don't even have proof of it helping as I still have many symptoms.
Is a gluten free diet a better way to go in general if you don't have celiac disease?
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#6 happygirl

 
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Posted 23 October 2008 - 01:48 PM

You probably need a follow up appointment to talk with your doctor. It may be necessary to do a biopsy of your small intestine to determine if you have Celiac Disease.

If your tTG was highly elevated, it would be easier to say with more certainty that it is probably Celiac. The AGA IgA test is a good test, but not as sensitive/specific.

I would recommend follow up care with a doctor knowledgable about Celiac.

How long have you been gluten free?
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