Get email alerts Get Celiac.com E-mail Alerts  




Celiac.com Sponsor:
Celiac.com Sponsor:




Ads by Google:






   Get email alerts  Subscribe to FREE Celiac.com email alerts

Ttg Results And Symptoms Relationship?
0

3 posts in this topic

Hi everyone,

I was just wondering what people's experiences have been regarding their tTG results and their symptoms after they have become gluten free...

Before going gluten-free, I had a tTG score of about 180 (where a high positive is > 30)

1.5 years later, my tTG is only 70, so still a strong positive but not as positive

My primary symptom of a [essentially constant] bloated/distended/uncomfortable gassy stomach did not change at all over that 1.5 years (i.e. I'm 6'2'', 170 lbs, and still wear pants with a 36 inch waist despite being a muscular guy).

My symptoms are the above mentioned bloated stomach and moderate constipation/sense of incomplete evacuation (the latter which is helped by miralax but alleviating the constipation has done little to help the other more concerning symptom).

--> Have other people had these symptoms and had a high tTG?

--> Will I have to wait until my tTG is much lower to experience any improvement?

Thanks guys

0

Share this post


Link to post
Share on other sites


Ads by Google:
--> Have other people had these symptoms and had a high tTG?

--> Will I have to wait until my tTG is much lower to experience any improvement?

Thanks guys

A year and a half seems a long time to not see any improvement. Are you certain you have eliminated all sources of gluten from your food-sources and medication?

Having said that, tTG can take a long time to normalise, a year or more is not unusual. Anti-gliadin IGA is more reactive and will normalise more quickly with removal of gluten from the diet (and vice versa), so it is better for use in monitoring the diet.

Have you considered you may be lactose or fructose intolerant? These can both cause bloating/gas. A lot of celiacs have lactose intolerance (mostly temporary) because of the damage to the villi, which normally release lactase enzyme from their tips.

There is a hydrogen breath test you can take to diagnose these, so maybe ask your doctor about it.

In regard to a link between high tTG and symptoms, in my case my tTG was >200 when diagnosed, and went down to 132 after four months. I never had any symptoms to speak of, apart from ongoing nausea and fatigue which I now put down to low B12, as it cleared once I had a course of B12 injections. The low B12 was most likely from malabsorption due to the gut damage.

0

Share this post


Link to post
Share on other sites

I know I'm a bit lactose intolerant and as such, have very little lactose containing products

My primary symptom of an uncomfortable distended bloated abdomen doesn't seem to cycle with what I eat that much --> it only seems to feel less uncomfortable if I avoid food in general

I've tried a 3 week elemental diet under the theory that this might be some sort of bacterial overgrowth but it didn't help (and such a diet would have been free of lactose/fructose/gluten for that time) -- I still felt pretty bloated during those three weeks making me think this symptom may be a function of ongoing inflammation as opposed to some sort of other process

also re: dietary compliance -- I was compliant as I could ever really be (my anti-gliadin was negative); if i became any more compliant I'd rule out eating out entirely (e.g. I would usually just eat mexican food like tacos which could have a spec of a gluten in them from a fleck of flour landing on them in the kitchen -- though if that's enough to set me off I should wear a mask everywhere...)

0

Share this post


Link to post
Share on other sites

Create an account or sign in to comment

You need to be a member in order to leave a comment

Create an account

Sign up for a new account in our community. It's easy!


Register a new account

Sign in

Already have an account? Sign in here.


Sign In Now
0

  • Forum Statistics

    • Total Topics
      104,110
    • Total Posts
      919,434
  • Topics

  • Posts

    • Hi Lisa, I completely understand why you didn't do a biopsy on your daughter.  I went through the appendix thing myself...not fun!  I was diagnosed with just bloodwork and no biopsy, but did have the full panel.  I would go back to your PCP and ask for a full panel to include TTG, EMA and DGP tests.  Since she was already willing to test you, I'm sure she would be willing to order these.  Good luck!
    • What a gross title–it bothers me and I wrote it! It wasn't my idea originally. The research paper the data came from was entitled, "Experimental hookworm infection and gluten microchallenge promote tolerance in celiac disease" published recently in the Journal of Allergy and Clinical Immunology. View the full article
    • katesyl.........this is an older topic so the OP most likely won't answer.  I can, however, offer a piece of advice for you. Just going gluten free will probably not drive your inflammation markers down into normal.  It does depend on how high they were to begin with but with all autoimmune diseases, there will be inflammation going on forever.  Get used to wonky blood work because most of us will have that issue. I have 4 autoimmune diseases in total and, although I have driven certain inflammatory markers way down, my recent sed rate number was elevated.  The normal is supposed to be 30 and under in a woman my age but mine is 50.  With 4 AI diseases, I doubt it will ever be normal and I don't let it bother me. I am not willing to take major meds at all and use more natural anti-inflammatory supplements.  You can do whatever you feel comfortable with in regards to treatment but don't expect normal numbers with Celiac Disease. Inflammation will improve but normal?  Most people never get there completely.
    • My daughter's PCP did not go against anything, she offered to do the biopsy - I was the one opposed to it. My DD, who was 10 at the time had just spent 3 weeks in the hospital, very sick with a ruptured appendix, then had 2 surgeries a few months after. I didn't see the need to put her through anything else with her numbers so high and all the classic symptoms. Apparently, in some other countries, if your numbers are all high, they forego biopsy. Anyway, I was really asking about myself and whether I should push for add'l testing. I am still new this this and trying to get up-to-date and wasn't sure if my PCP should conduct other blood tests before I go completely gluten-free. I have been somewhat gluten-free, but not entirely. I have no problem going gluten-free, but want to make sure that I am doing it for the right reasons. I wasn't sure if the Gliadin Abs IgA was sufficient to point to Celiac and possibly doing a biopsy for me. Or if additional blood test would make more sense.   Thanks!!
    • I would like to know if you have found out the source of your inflammation yet. I'm gluten free three years but my inflammation test was high.
  • Blog Entries

  • Recent Status Updates

  • Who's Online (See full list)

  • Member Statistics

    • Total Members
      61,149
    • Most Online
      1,763

    Newest Member
    Caspi-Ann
    Joined